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The map label for this gene is cofC

Identifier: 169630370

GI number: 169630370

Start: 3327466

End: 3328080

Strand: Direct

Name: cofC

Synonym: MAB_3289

Alternate gene names: 169630370

Gene position: 3327466-3328080 (Clockwise)

Preceding gene: 169630366

Following gene: 169630371

Centisome position: 65.67

GC content: 69.11

Gene sequence:

>615_bases
GTGGGCAGACAGGCTGGCACAGACTTCGGCGTGATCATCGCGGTCAAGAACCTGGCGACCGCGAAGAGCCGGCTGGCACC
GTCCCTGCCCGCGCCGCAACGAGAGCGGTTGGTGCTGGGCATGCTCACGCACGCCATCGCCGTGGCGTTCAGCGCCGCCG
GAACCGTGGCAGTGATCAGCCCCGATCCGACGGCCAAGGCGGCAGCCAGCGAGGCCGGTGCCCGGTTCATCTTCGATGAC
ACACCCGAAGGCCACCCCGACCCGCTGAACAACGCATTGCGCAGCGCCGCCGCGCAGCTACGTGCGTCCTCACCGAATCT
TGTTGTGTTGCAGGCCGACCTTCCCGTGGTAACCGCCACGGAGTTCGCGGCGGCGCTCGCGGCCGCGCGGGGCCACGCGC
GCAGTTTCGTCGCCGACCGGCACGGCACGGGCACCGCGGCACTTTTCAGCACCGACGGCGACCTGAATCCGCTGTTCGGA
ATCGATTCGGCACAGCGGCACCGAGATTCAGGGGCCATTGAACTCACCGGAGACTGGCCCGGATTGCGTTGCGACGTGGA
CACCCCGGAAGATCTGGCCGTGGCCCGCGAGCTGGGGGCCGCGCTGCCGCTCTGA

Upstream 100 bases:

>100_bases
ACCAGCACCCATCACCGCAGCTTTGACTGGTCGTCTTCCCGCAAGCGGCTCATCCGTGGCCATGGCAGACACCCTAGCCG
GGGCTGGCACCATGGAGTAC

Downstream 100 bases:

>100_bases
GCCGGCCCGATAACTCTATGATCACAAGGGTGACCACACCGAGCGTTCCCCCCGCCGCAACCACCATCGTGTCGGGTGAA
GAGCTGCCCGAAGACCGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MGRQAGTDFGVIIAVKNLATAKSRLAPSLPAPQRERLVLGMLTHAIAVAFSAAGTVAVISPDPTAKAAASEAGARFIFDD
TPEGHPDPLNNALRSAAAQLRASSPNLVVLQADLPVVTATEFAAALAAARGHARSFVADRHGTGTAALFSTDGDLNPLFG
IDSAQRHRDSGAIELTGDWPGLRCDVDTPEDLAVARELGAALPL

Sequences:

>Translated_204_residues
MGRQAGTDFGVIIAVKNLATAKSRLAPSLPAPQRERLVLGMLTHAIAVAFSAAGTVAVISPDPTAKAAASEAGARFIFDD
TPEGHPDPLNNALRSAAAQLRASSPNLVVLQADLPVVTATEFAAALAAARGHARSFVADRHGTGTAALFSTDGDLNPLFG
IDSAQRHRDSGAIELTGDWPGLRCDVDTPEDLAVARELGAALPL
>Mature_203_residues
GRQAGTDFGVIIAVKNLATAKSRLAPSLPAPQRERLVLGMLTHAIAVAFSAAGTVAVISPDPTAKAAASEAGARFIFDDT
PEGHPDPLNNALRSAAAQLRASSPNLVVLQADLPVVTATEFAAALAAARGHARSFVADRHGTGTAALFSTDGDLNPLFGI
DSAQRHRDSGAIELTGDWPGLRCDVDTPEDLAVARELGAALPL

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COFC_MYCA9 (B1MDP6)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001704019.1
- ProteinModelPortal:   B1MDP6
- SMR:   B1MDP6
- EnsemblBacteria:   EBMYCT00000008799
- GeneID:   5965789
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3289
- GeneTree:   EBGT00050000017164
- HOGENOM:   HBG699055
- OMA:   LNADLPA
- ProtClustDB:   CLSK792205
- BioCyc:   MABS561007:MAB_3289-MONOMER
- HAMAP:   MF_02114
- InterPro:   IPR002835
- TIGRFAMs:   TIGR03552

Pfam domain/function: PF01983 DUF121

EC number: =2.7.7.68

Molecular weight: Translated: 20962; Mature: 20831

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRQAGTDFGVIIAVKNLATAKSRLAPSLPAPQRERLVLGMLTHAIAVAFSAAGTVAVIS
CCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PDPTAKAAASEAGARFIFDDTPEGHPDPLNNALRSAAAQLRASSPNLVVLQADLPVVTAT
CCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHH
EFAAALAAARGHARSFVADRHGTGTAALFSTDGDLNPLFGIDSAQRHRDSGAIELTGDWP
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCEEEECCCC
GLRCDVDTPEDLAVARELGAALPL
CEEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GRQAGTDFGVIIAVKNLATAKSRLAPSLPAPQRERLVLGMLTHAIAVAFSAAGTVAVIS
CCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEC
PDPTAKAAASEAGARFIFDDTPEGHPDPLNNALRSAAAQLRASSPNLVVLQADLPVVTAT
CCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEHH
EFAAALAAARGHARSFVADRHGTGTAALFSTDGDLNPLFGIDSAQRHRDSGAIELTGDWP
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCCEEEECCCC
GLRCDVDTPEDLAVARELGAALPL
CEEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA