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The map label for this gene is coaD

Identifier: 169630340

GI number: 169630340

Start: 3297645

End: 3298130

Strand: Reverse

Name: coaD

Synonym: MAB_3259c

Alternate gene names: 169630340

Gene position: 3298130-3297645 (Counterclockwise)

Preceding gene: 169630341

Following gene: 169630339

Centisome position: 65.09

GC content: 62.14

Gene sequence:

>486_bases
ATGACGGGAGCGGTGTGCCCCGGCTCGTTCGATCCGGTGACCCTTGGGCACCTGGATGTGTTCGAACGAGCCGCGGCGCA
GTTCGACGAGGTGATTGTCGCCGTGCTCATCAACCCGAACAAAGCGGGCATGTTCACCGTTGACGAGCGCATCGAGATGA
TCCGCGAGTCCACGGCCGACCTGCCCAATCTGCGGGTCGAGTCGGGGCAGGGTCTGCTGGTGGACTTTGTCAGGGAACGG
GGCCTGAACGCGATCGTGAAGGGACTGCGTACCGGCACCGACTTCGAGTACGAGCTTCAGATGGCTCAGATGAACAAGCA
CATCGCCGGGGTCGACACATTTTTCGTCGCTACCGCGCCCGCGTATTCGTTCGTCTCGTCGTCGCTCGCGAAGGAGGTGG
CGACGTACGGGGGAGATGTCTCGGCGTTGCTGCCTGCTTCCGTTCACCAACGACTTCTCGGGAAACTGCGTGGCCAGGCA
CAATAG

Upstream 100 bases:

>100_bases
TCGTCACCCTCACTCTGGTAGTGGGCATCTGGCTTATCGTGATCGGCGTGATGCAAATCGGAAGCGGTATCGGCATTCGC
GCGGCCACCAAATCGGCCGT

Downstream 100 bases:

>100_bases
AAAACAGGCCGCGCAGAAATAGCCGACACACCGGTCAGCTAGCACGGTCACAGCAGTCACACCAGGCACACTGGTAACAG
TGGAAACTCGCGTGAAGGGT

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRER
GLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQA
Q

Sequences:

>Translated_161_residues
MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRER
GLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQA
Q
>Mature_160_residues
TGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTADLPNLRVESGQGLLVDFVRERG
LNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAPAYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQAQ

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=154, Percent_Identity=43.5064935064935, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_MYCA9 (B1MDL6)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001703989.1
- ProteinModelPortal:   B1MDL6
- SMR:   B1MDL6
- EnsemblBacteria:   EBMYCT00000007612
- GeneID:   5965760
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_3259c
- GeneTree:   EBGT00050000017247
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   MABS561007:MAB_3259C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17373; Mature: 17242

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTAD
CCCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHHHHHHHCC
LPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAP
CCCCEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCHHCCHHHHHHHHHH
AYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQAQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TGAVCPGSFDPVTLGHLDVFERAAAQFDEVIVAVLINPNKAGMFTVDERIEMIRESTAD
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEHHHHHHHHHHHHCC
LPNLRVESGQGLLVDFVRERGLNAIVKGLRTGTDFEYELQMAQMNKHIAGVDTFFVATAP
CCCCEECCCCCHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCHHCCHHHHHHHHHH
AYSFVSSSLAKEVATYGGDVSALLPASVHQRLLGKLRGQAQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA