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The map label for this gene is kdpE [H]

Identifier: 169630331

GI number: 169630331

Start: 3286748

End: 3287422

Strand: Reverse

Name: kdpE [H]

Synonym: MAB_3250c

Alternate gene names: 169630331

Gene position: 3287422-3286748 (Counterclockwise)

Preceding gene: 169630332

Following gene: 169630329

Centisome position: 64.88

GC content: 64.74

Gene sequence:

>675_bases
ATGACCCGGGTGCTGGTGGTGGACGACGAGCCGCAGATTCTGCGCGCCATGCGCATAAACCTGTCGGCACGCGGATATGA
GGTAGTGACAGCCTCCTCCGGCGCCGGAGCGCTGCGCGCGGCGGCCGAGACCCAGCCCGAAGTGGTCATTCTGGACCTCG
GATTGCCCGATATGGACGGCACCGAGGTACTCGCCGGGCTGCGTGGCTGGACCGACGTGCCGGTGATCGTGCTCTCGGCC
CGCACCGATTCCGCGGACAAGGTGGAGGCGTTGGACGCCGGTGCCGACGATTACGTGACCAAACCCTTCGGCATGGATGA
GTTTTTGGCCCGGCTCCGGGCCGCGGTACGCCGAGGCACCCCTGACAGTGCCGAGCCGGTGGTCCATACCGAGACCTTCG
ACGTGGATCTTTCCTCGCACAAGGTGATCCGCGACGGCAGAGAGGTACACCTGACACCCACCGAATGGTCGATGCTGGCT
GTGCTGGTGCGCAATCGTGGAAAGCTGGTGGGGCAGAAGGAGCTGTTGCACGAGGTATGGGGCCCGGCGTACAGCTCCGA
AACTCATTACTTGCGTGTGTATCTCGCGCAGCTGCGGCGCAAGCTGGAAATCGACCCGGCGCACCCCAAGCATCTGCTCA
CCGAGGCGGGGATGGGCTATCGCTTCCAGGAGTGA

Upstream 100 bases:

>100_bases
CGATGGAGGGCACGGTGAATGCGACCGACACGGCTGGCGGCGGACTGACCATGATCGTGGATCTACCCAGCGCTGGTTCC
GCTCCTACCGGGGCGATCCG

Downstream 100 bases:

>100_bases
TCCGTCAGAACGGCGGACGGCCGAGATCGATCTGCTGGACGTCGGGGTCGCAACCGGGCCGGTACTTGGGTACCAACTGC
CCGTAGGTGGCGCGGAAATT

Product: transcriptional regulatory protein KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSA
RTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGTPDSAEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLA
VLVRNRGKLVGQKELLHEVWGPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE

Sequences:

>Translated_224_residues
MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSA
RTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGTPDSAEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLA
VLVRNRGKLVGQKELLHEVWGPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE
>Mature_223_residues
TRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDGTEVLAGLRGWTDVPVIVLSAR
TDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGTPDSAEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLAV
LVRNRGKLVGQKELLHEVWGPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=51.1210762331839, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=36.283185840708, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.7354260089686, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.0909090909091, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=31.2775330396476, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.5315315315315, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=28.5087719298246, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=30.5936073059361, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.9559471365639, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=31.4159292035398, Blast_Score=102, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=29.8245614035088, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=31.0502283105023, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=39.4495412844037, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=22.3175965665236, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=35.0877192982456, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788905, Length=123, Percent_Identity=34.1463414634146, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=132, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24767; Mature: 24635

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDG
CCEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCH
TEVLAGLRGWTDVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGT
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PDSAEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVW
CCCCCCEEEEEEEEEECCCCHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHC
GPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECC
>Mature Secondary Structure 
TRVLVVDDEPQILRAMRINLSARGYEVVTASSGAGALRAAAETQPEVVILDLGLPDMDG
CEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCH
TEVLAGLRGWTDVPVIVLSARTDSADKVEALDAGADDYVTKPFGMDEFLARLRAAVRRGT
HHHHHHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PDSAEPVVHTETFDVDLSSHKVIRDGREVHLTPTEWSMLAVLVRNRGKLVGQKELLHEVW
CCCCCCEEEEEEEEEECCCCHHCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHC
GPAYSSETHYLRVYLAQLRRKLEIDPAHPKHLLTEAGMGYRFQE
CCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]