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The map label for this gene is lrhA [H]

Identifier: 169630261

GI number: 169630261

Start: 3224891

End: 3225757

Strand: Reverse

Name: lrhA [H]

Synonym: MAB_3179c

Alternate gene names: 169630261

Gene position: 3225757-3224891 (Counterclockwise)

Preceding gene: 169630264

Following gene: 169630258

Centisome position: 63.66

GC content: 65.86

Gene sequence:

>867_bases
ATGGCGAGTTCGACGTTCGATATCGCGCCGCTGCGGTCGCTGGCGGCGGTCGCCGATTGCGGGGGATTCCACCGCGCCGC
CGCTGTGCTGCACCTGACCCAATCCGCGGTCAGTCAGCATGTACGCAAGCTCGAGACGGCGATCGGGGAGCCGGTGGTTC
GGCGCTATGGACGCGGCGTGGTGTTCACCGACAGGGGCGCCCGGCTGCTGGTGCATGCCCGGCGCATCTTGGCCGCACAC
GATGCCGCGGTCGATGATTTGGTGGCCGGCCAGGAACGCGCCCTGGTTTTGGGCGTCACCGAACATGGCGCGGACTTGAT
CTTGCCGAGCATCACCTCGGCCCTGCGAAGCCATCTTCCGGATTGGTCGGTGCGTGTGCGCTTCGATCGCAATCTTTATC
TCGCCGAATCCGTGGACCGGGGAATCATGGACCTTGCGGTCATCCTGGACGGATCGGGCCTGGATCGCGCCAATGCGGTG
GGCACCGTTCCGCTGCAGTGGGTTGCCGCACGCGGCTACAAGCCGAATCCCATTGAGCCCCTGCGGGTGATGACGTTCAC
CGAGCCGTGCACGCTGCGTGCGCCCATGTTCAGTGCCTTGCATACGCTGGGAAATCAGTACCAGATCGTCGGAGAATCAC
CGGATTTGTCCGGTCTGTACGCGGGACTGCGGTCGGGCCTGGGCATGGCGCTGCTGCCCATCATCGGGTGGTTGCCCGAC
GGTATCGCACCGGTTGACGCCATGCCCGCGGCGAACCTGGCGACGCTATCGGTCGTCGGTCGCCGCGGGCTGGACCCCGT
CGCGTTCAATGCTGTGAAGGATGCTGCCCGCGAGGCCCTCTCGGGTGAATCGGCGGCTATCGCCTAA

Upstream 100 bases:

>100_bases
ATACTTATCACTCAAGACGAAATCTGCGTTTGAAATGGGAATATTTCCCTTCATTGTCTCAGGCATTGATCAAATTTTGT
GATCGAGTTAGCGTGTCGAT

Downstream 100 bases:

>100_bases
GCCGATTCCGTCGTGGGCTTGCGCTCGGCCCGCAGCACGGTGTCTGCGATATCAAACTCCTCGTCGTCACGCGTGAACTT
TCGGCTCCGTGATTCGGCGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGVVFTDRGARLLVHARRILAAH
DAAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAESVDRGIMDLAVILDGSGLDRANAV
GTVPLQWVAARGYKPNPIEPLRVMTFTEPCTLRAPMFSALHTLGNQYQIVGESPDLSGLYAGLRSGLGMALLPIIGWLPD
GIAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA

Sequences:

>Translated_288_residues
MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGVVFTDRGARLLVHARRILAAH
DAAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAESVDRGIMDLAVILDGSGLDRANAV
GTVPLQWVAARGYKPNPIEPLRVMTFTEPCTLRAPMFSALHTLGNQYQIVGESPDLSGLYAGLRSGLGMALLPIIGWLPD
GIAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA
>Mature_287_residues
ASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGVVFTDRGARLLVHARRILAAHD
AAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAESVDRGIMDLAVILDGSGLDRANAVG
TVPLQWVAARGYKPNPIEPLRVMTFTEPCTLRAPMFSALHTLGNQYQIVGESPDLSGLYAGLRSGLGMALLPIIGWLPDG
IAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=248, Percent_Identity=30.6451612903226, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1788297, Length=239, Percent_Identity=25.5230125523013, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30501; Mature: 30370

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
VFTDRGARLLVHARRILAAHDAAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLP
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
DWSVRVRFDRNLYLAESVDRGIMDLAVILDGSGLDRANAVGTVPLQWVAARGYKPNPIEP
CCEEEEEECCCEEEHHHHCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
LRVMTFTEPCTLRAPMFSALHTLGNQYQIVGESPDLSGLYAGLRSGLGMALLPIIGWLPD
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCC
GIAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGV
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCE
VFTDRGARLLVHARRILAAHDAAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLP
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCC
DWSVRVRFDRNLYLAESVDRGIMDLAVILDGSGLDRANAVGTVPLQWVAARGYKPNPIEP
CCEEEEEECCCEEEHHHHCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
LRVMTFTEPCTLRAPMFSALHTLGNQYQIVGESPDLSGLYAGLRSGLGMALLPIIGWLPD
EEEEEECCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCC
GIAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]