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The map label for this gene is pgsA2 [H]

Identifier: 169630154

GI number: 169630154

Start: 3117929

End: 3118528

Strand: Reverse

Name: pgsA2 [H]

Synonym: MAB_3071c

Alternate gene names: 169630154

Gene position: 3118528-3117929 (Counterclockwise)

Preceding gene: 169630157

Following gene: 169630152

Centisome position: 61.54

GC content: 63.33

Gene sequence:

>600_bases
GTGCCGATGCCACCGGAAACCCAGCCTGATTCGGCGGCTTCGGCTGCGCCGGTGCCGGTGCTGAACATAGCCAACATCCT
GACCGTGCTACGCATCGTGCTGGTGCCGGTGTTCGTTGTGGTGCTCTTTACCGAGGGCGGGCATCAAAGCTCCTGGCGCA
TTGCCGCTTTTGGAGTGTTCGCGCTGGCCATCGCCACTGACCGGTATGACGGCATACTTGCCCGCCGCTACGGCCTGATA
ACCCCATTCGGTCAGCTCGCAGACCCTATAGCCGATAAGGCCCTTATCTGCGCGGCGCTGGTGGGGCTGAGTCTGCTCGG
CGATCTGTCGTGGTGGGTCACCGCGGTCATCCTGGTCCGCGAGATCGGAATCACCGTCTTGCGCTTCTCCGTGCTGCGCC
ATGGTGTGATTCCGGCGAACCGGGGTGGCAAGCTCAAAACCTTGGTGCAGTCGTTGGCGATCGCGGGCTATCTGCTGCCG
CTGACCGGCCACTGGCACACCGCTGCGCTGATCTTGATGGGATTGGCGGTGGCCCTCACCGTCATCACCGGTATCGACTA
TTTGGTCCAGGCGCTGCGCCCACGGCCGAAAACCCCCTAG

Upstream 100 bases:

>100_bases
CCGCGGGGGCGGGATGCCCCGGATTGTCCGAGATGCCGGATGTACCTTCAGCGCTCATGCGTGAACAGTAGCCAGCTCAC
GAACAGATAGGGTGTTTGAC

Downstream 100 bases:

>100_bases
ATTCCCGCCGCTGGAATCGGCGGTCATGGTGCTGCCGGTCGATTAGCGTTTTTCAGGTGAAGGTGACACCGGTCAGTTCC
TGGGATGCCTGCCACAGTCG

Product: PGP synthase PgsA3 (phosphatidylglycerophosphate synthase)

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MPMPPETQPDSAASAAPVPVLNIANILTVLRIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLI
TPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFSVLRHGVIPANRGGKLKTLVQSLAIAGYLLP
LTGHWHTAALILMGLAVALTVITGIDYLVQALRPRPKTP

Sequences:

>Translated_199_residues
MPMPPETQPDSAASAAPVPVLNIANILTVLRIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLI
TPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFSVLRHGVIPANRGGKLKTLVQSLAIAGYLLP
LTGHWHTAALILMGLAVALTVITGIDYLVQALRPRPKTP
>Mature_198_residues
PMPPETQPDSAASAAPVPVLNIANILTVLRIVLVPVFVVVLFTEGGHQSSWRIAAFGVFALAIATDRYDGILARRYGLIT
PFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVREIGITVLRFSVLRHGVIPANRGGKLKTLVQSLAIAGYLLPL
TGHWHTAALILMGLAVALTVITGIDYLVQALRPRPKTP

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=179, Percent_Identity=36.8715083798883, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21212; Mature: 21080

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPPETQPDSAASAAPVPVLNIANILTVLRIVLVPVFVVVLFTEGGHQSSWRIAAFGVF
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALAIATDRYDGILARRYGLITPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGITVLRFSVLRHGVIPANRGGKLKTLVQSLAIAGYLLPLTGHWHTAALILMGLAVALT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VITGIDYLVQALRPRPKTP
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMPPETQPDSAASAAPVPVLNIANILTVLRIVLVPVFVVVLFTEGGHQSSWRIAAFGVF
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ALAIATDRYDGILARRYGLITPFGQLADPIADKALICAALVGLSLLGDLSWWVTAVILVR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGITVLRFSVLRHGVIPANRGGKLKTLVQSLAIAGYLLPLTGHWHTAALILMGLAVALT
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VITGIDYLVQALRPRPKTP
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]