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The map label for this gene is ykgC [H]

Identifier: 169630097

GI number: 169630097

Start: 3071220

End: 3072596

Strand: Direct

Name: ykgC [H]

Synonym: MAB_3014

Alternate gene names: 169630097

Gene position: 3071220-3072596 (Clockwise)

Preceding gene: 169630096

Following gene: 169630098

Centisome position: 60.61

GC content: 65.43

Gene sequence:

>1377_bases
GTGAGCACACATTTCGATGCTGTCGTGGTGGGTGCCGGGCAGGCCGGCCCTTCGCTGGCCGCACGGCTGCGCGGGGCGGG
TCTGACCGTGGCGATCGTGGAACGGCACCTGTTCGGCGGCACCTGCGTGAACACCGGATGCCGGCCCACCAAGGCACTGG
TCGCCAGCGCCCATGCCGCCCATATGGCGCGTGAGGCCGCACGCTGGGGCGTCGTCGTCGATGGCTCCGTGAGCATGGAC
ATGGTCCGGGTACGGGAACGCAAGGATGCGGTGATCCTGCCCTCACGCAACGGCGGACAGACGTGGCTCAAGGACCTGGG
TTGCGCGATCTACCACGAACACGCGAGCTTTCTATCCCCGACCGAACTTTCCGTGGGCGACGAGATCATCTCCGCCGAAA
GGATTTTCCTGAACGTCGGCGGCCGCGCGGTGGTCCCTGACTGGCCCGGGGTCGATGACGTCCCGCTGTTCACCAACAGC
TCACTGATCGAGTACGACGGGATACCGGAGCATCTCGTGGTGATCGGAGGCAGCTACGTCGGCCTGGAATTCGCACAGAT
CTACCGCCGGTTCGGCAGCCAGGTCACGGTGGTGCACCGCGGGCCTCGGCTGGTGGAGCGTGAAGACCCCGACGCGTCGG
CGATCATTCAGGAGGTCCTCGAGCGTGAGGGAATCACCTTCCGTCTCAATGCCTCCTGTATCAACCTGGCACGCCATGAC
GAGGGTGTTGCCGTGGGCGTCGATTGCACGGACGGTGCGCCCAAGGTGGTGGGGTCTCATGTGCTCGTGGCGGTGGGACG
CCGCCCGAACACCGACGACCTAGGCCTGGAGAACGCCGGGGTTGCCACCGACGCCCGCGGGTACATCACGGTCGACGATC
AGTTGCGCACGAGCACACCGGGGATCTGGGCGCTCGGCGACTGCAACGGCCGTGGCGCCTTCACACATACCTCGTACAAC
GATTTCGAGATCGTCGCCGCGAACCTTCTGGACGACGATCCGCGACGCGTCACCGATAGGCTGCCGTGCTACGCGCTGTA
CACCGATCCGCCCCTCGGACGAGTGGGCATGACCGAGGCGCAGGCACGCGCTTCGGGGCGCTCCCTGCTGGTCGGACGCA
AGCCGATGAGCCACGTCGGCCGCGCCCTGGAAAAAGGTGAAACCGACGGCTATATGCAGGTTTTGGTCGACGCGGACTCC
GATCTCATTCTGGGCGCGACGATCCTCGGCGTGGGTGGCGATGAGGTGGTGCACTGCTTGCTCGACACCATGCAGTACGG
CATTCCCGCGCGACAATTGCAGCGCACCGTCCATATCCACCCCACTGTGGCGGAGTTCCTGCCGACGATCTTGGGTGAGC
TTCAGCCGCTGATTTGA

Upstream 100 bases:

>100_bases
GAGCATTGGCCACCGCCTTCGGTAAGGACCTGCCGGCCGCACTCATCGAGGACGCGATCACCGTGGCGGCGGCCCTCGCG
ATCACCGCGGGACTGGCCAC

Downstream 100 bases:

>100_bases
CCTCAAGTGCACTTGAGAAAATAGCGTAGCTGCCATGAGGATTCGGGATGTGCAGATCACGGCTACGGACCTTCCGGGGG
CCGCGCGCTTCTACTCCGAA

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSTHFDAVVVGAGQAGPSLAARLRGAGLTVAIVERHLFGGTCVNTGCRPTKALVASAHAAHMAREAARWGVVVDGSVSMD
MVRVRERKDAVILPSRNGGQTWLKDLGCAIYHEHASFLSPTELSVGDEIISAERIFLNVGGRAVVPDWPGVDDVPLFTNS
SLIEYDGIPEHLVVIGGSYVGLEFAQIYRRFGSQVTVVHRGPRLVEREDPDASAIIQEVLEREGITFRLNASCINLARHD
EGVAVGVDCTDGAPKVVGSHVLVAVGRRPNTDDLGLENAGVATDARGYITVDDQLRTSTPGIWALGDCNGRGAFTHTSYN
DFEIVAANLLDDDPRRVTDRLPCYALYTDPPLGRVGMTEAQARASGRSLLVGRKPMSHVGRALEKGETDGYMQVLVDADS
DLILGATILGVGGDEVVHCLLDTMQYGIPARQLQRTVHIHPTVAEFLPTILGELQPLI

Sequences:

>Translated_458_residues
MSTHFDAVVVGAGQAGPSLAARLRGAGLTVAIVERHLFGGTCVNTGCRPTKALVASAHAAHMAREAARWGVVVDGSVSMD
MVRVRERKDAVILPSRNGGQTWLKDLGCAIYHEHASFLSPTELSVGDEIISAERIFLNVGGRAVVPDWPGVDDVPLFTNS
SLIEYDGIPEHLVVIGGSYVGLEFAQIYRRFGSQVTVVHRGPRLVEREDPDASAIIQEVLEREGITFRLNASCINLARHD
EGVAVGVDCTDGAPKVVGSHVLVAVGRRPNTDDLGLENAGVATDARGYITVDDQLRTSTPGIWALGDCNGRGAFTHTSYN
DFEIVAANLLDDDPRRVTDRLPCYALYTDPPLGRVGMTEAQARASGRSLLVGRKPMSHVGRALEKGETDGYMQVLVDADS
DLILGATILGVGGDEVVHCLLDTMQYGIPARQLQRTVHIHPTVAEFLPTILGELQPLI
>Mature_457_residues
STHFDAVVVGAGQAGPSLAARLRGAGLTVAIVERHLFGGTCVNTGCRPTKALVASAHAAHMAREAARWGVVVDGSVSMDM
VRVRERKDAVILPSRNGGQTWLKDLGCAIYHEHASFLSPTELSVGDEIISAERIFLNVGGRAVVPDWPGVDDVPLFTNSS
LIEYDGIPEHLVVIGGSYVGLEFAQIYRRFGSQVTVVHRGPRLVEREDPDASAIIQEVLEREGITFRLNASCINLARHDE
GVAVGVDCTDGAPKVVGSHVLVAVGRRPNTDDLGLENAGVATDARGYITVDDQLRTSTPGIWALGDCNGRGAFTHTSYND
FEIVAANLLDDDPRRVTDRLPCYALYTDPPLGRVGMTEAQARASGRSLLVGRKPMSHVGRALEKGETDGYMQVLVDADSD
LILGATILGVGGDEVVHCLLDTMQYGIPARQLQRTVHIHPTVAEFLPTILGELQPLI

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=457, Percent_Identity=28.0087527352298, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI50301238, Length=464, Percent_Identity=27.1551724137931, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI148277065, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI33519430, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI33519428, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI33519426, Length=433, Percent_Identity=24.9422632794457, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI148277071, Length=430, Percent_Identity=24.8837209302326, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI22035672, Length=437, Percent_Identity=27.6887871853547, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI291045266, Length=438, Percent_Identity=23.0593607305936, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI291045268, Length=433, Percent_Identity=24.0184757505774, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87081717, Length=452, Percent_Identity=34.7345132743363, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1786307, Length=458, Percent_Identity=30.3493449781659, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789915, Length=457, Percent_Identity=26.9146608315098, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87082354, Length=456, Percent_Identity=26.3157894736842, Blast_Score=145, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI32565766, Length=456, Percent_Identity=28.7280701754386, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71983429, Length=458, Percent_Identity=25.764192139738, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71983419, Length=458, Percent_Identity=25.764192139738, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17557007, Length=472, Percent_Identity=24.7881355932203, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71982272, Length=446, Percent_Identity=22.8699551569507, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17559934, Length=230, Percent_Identity=27.8260869565217, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321091, Length=460, Percent_Identity=29.7826086956522, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6325166, Length=467, Percent_Identity=22.4839400428266, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325240, Length=469, Percent_Identity=22.6012793176972, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI21358499, Length=460, Percent_Identity=30.4347826086957, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24640549, Length=469, Percent_Identity=26.6524520255864, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24640553, Length=469, Percent_Identity=26.6524520255864, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24640551, Length=469, Percent_Identity=26.4392324093817, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17737741, Length=472, Percent_Identity=26.9067796610169, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 49088; Mature: 48957

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHFDAVVVGAGQAGPSLAARLRGAGLTVAIVERHLFGGTCVNTGCRPTKALVASAHAA
CCCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEHHHHCCCCEECCCCCHHHHHHHHHHHH
HMAREAARWGVVVDGSVSMDMVRVRERKDAVILPSRNGGQTWLKDLGCAIYHEHASFLSP
HHHHHHHHCCEEECCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHEEEHHHHCCCC
TELSVGDEIISAERIFLNVGGRAVVPDWPGVDDVPLFTNSSLIEYDGIPEHLVVIGGSYV
CCCCCCHHHHCCEEEEEEECCEEECCCCCCCCCCCEECCCCEEEECCCCCEEEEECCCHH
GLEFAQIYRRFGSQVTVVHRGPRLVEREDPDASAIIQEVLEREGITFRLNASCINLARHD
HHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEHEECC
EGVAVGVDCTDGAPKVVGSHVLVAVGRRPNTDDLGLENAGVATDARGYITVDDQLRTSTP
CCEEEEEECCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GIWALGDCNGRGAFTHTSYNDFEIVAANLLDDDPRRVTDRLPCYALYTDPPLGRVGMTEA
CEEEEECCCCCCCEEECCCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCHH
QARASGRSLLVGRKPMSHVGRALEKGETDGYMQVLVDADSDLILGATILGVGGDEVVHCL
HHHCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHH
LDTMQYGIPARQLQRTVHIHPTVAEFLPTILGELQPLI
HHHHHHCCCHHHHCCEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STHFDAVVVGAGQAGPSLAARLRGAGLTVAIVERHLFGGTCVNTGCRPTKALVASAHAA
CCCCCEEEEECCCCCHHHHHHHCCCCEEEEEEHHHHCCCCEECCCCCHHHHHHHHHHHH
HMAREAARWGVVVDGSVSMDMVRVRERKDAVILPSRNGGQTWLKDLGCAIYHEHASFLSP
HHHHHHHHCCEEECCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHCCHHEEEHHHHCCCC
TELSVGDEIISAERIFLNVGGRAVVPDWPGVDDVPLFTNSSLIEYDGIPEHLVVIGGSYV
CCCCCCHHHHCCEEEEEEECCEEECCCCCCCCCCCEECCCCEEEECCCCCEEEEECCCHH
GLEFAQIYRRFGSQVTVVHRGPRLVEREDPDASAIIQEVLEREGITFRLNASCINLARHD
HHHHHHHHHHHCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCEEEHEECC
EGVAVGVDCTDGAPKVVGSHVLVAVGRRPNTDDLGLENAGVATDARGYITVDDQLRTSTP
CCEEEEEECCCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCC
GIWALGDCNGRGAFTHTSYNDFEIVAANLLDDDPRRVTDRLPCYALYTDPPLGRVGMTEA
CEEEEECCCCCCCEEECCCCCEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCHH
QARASGRSLLVGRKPMSHVGRALEKGETDGYMQVLVDADSDLILGATILGVGGDEVVHCL
HHHCCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEEEECCHHHHHHHH
LDTMQYGIPARQLQRTVHIHPTVAEFLPTILGELQPLI
HHHHHHCCCHHHHCCEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]