Click here to switch to the map view.

The map label for this gene is cat [H]

Identifier: 169630072

GI number: 169630072

Start: 3049437

End: 3050126

Strand: Direct

Name: cat [H]

Synonym: MAB_2989

Alternate gene names: 169630072

Gene position: 3049437-3050126 (Clockwise)

Preceding gene: 169630071

Following gene: 169630077

Centisome position: 60.18

GC content: 59.86

Gene sequence:

>690_bases
GTGCCCGCCGAACACGCTCTGCTGGTGGTCATGGCGACCTTCGAACCCCTCGATCTGCAGCAGTGGCCGCGACGAGAATG
GTTCGAACACTATCTGGATCGCTGCCCCACCTACTACTCGATGACGGTGGACTTGGATATCACGAATCTGAGGGCGGCGG
TGGACGCATCCGGTCGCAAGACGTATCCCACGCAGATTTGGGCATTGGCCACCGTGGTGAATCGTCACCCGGAATTCCGT
ATGGCACTGGACGATCAGGGCAACCCAGGGGTGTGGGACGTGGTGGACCCGGCATTCACGGTCTTCAACCCCGATCGCGA
GACCTTCGCCGGTATCAGTGCGCGCTACACACCTGATTTCGACGCTTTTCATTCCGAGGCCGCCGAGCTGCTGAGCGAAT
ATCGTAATGCTTCAACACTTTTCCCACAGGGTGCGCCACGTCCACGCAACGTGTTCGATATCTCGAGCATCCCCTGGACA
CGCTTTACCGGCTTCACACTCACCATCGCCCCAGGCTGGGCACACCTGGCGCCCATCTTCACCATCGGCAAGTTCTACGA
ACAAGAAGGCCGAACCATGATGCCGCTAGCCCTACAGATTCATCACGCGGCCGCCGATGGCTATCACAGCGCACGCTTGG
TCGAGGAGCTCCGCCAAATCATCGCCGATCCGGATTGGGTCCGGGACTAG

Upstream 100 bases:

>100_bases
ACGGCGCACGTCCCTGGCAGCGGCAGCTGACCGTCCCCCTCCTGACCGAAGCGCTGGCGGACTAGCGCCCTCTGCGCCGC
CGGTCAAAACTCGGTTGCGC

Downstream 100 bases:

>100_bases
TCGACCTGCTGCGCGGCGGGGTTCACGGTGCTGTCTCCGATTTCGCGGCTCATCGCGGCCACCCAGCCGGTGATCTTGCG
GGCGATGTGCTGATCGGTGA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPAEHALLVVMATFEPLDLQQWPRREWFEHYLDRCPTYYSMTVDLDITNLRAAVDASGRKTYPTQIWALATVVNRHPEFR
MALDDQGNPGVWDVVDPAFTVFNPDRETFAGISARYTPDFDAFHSEAAELLSEYRNASTLFPQGAPRPRNVFDISSIPWT
RFTGFTLTIAPGWAHLAPIFTIGKFYEQEGRTMMPLALQIHHAAADGYHSARLVEELRQIIADPDWVRD

Sequences:

>Translated_229_residues
MPAEHALLVVMATFEPLDLQQWPRREWFEHYLDRCPTYYSMTVDLDITNLRAAVDASGRKTYPTQIWALATVVNRHPEFR
MALDDQGNPGVWDVVDPAFTVFNPDRETFAGISARYTPDFDAFHSEAAELLSEYRNASTLFPQGAPRPRNVFDISSIPWT
RFTGFTLTIAPGWAHLAPIFTIGKFYEQEGRTMMPLALQIHHAAADGYHSARLVEELRQIIADPDWVRD
>Mature_228_residues
PAEHALLVVMATFEPLDLQQWPRREWFEHYLDRCPTYYSMTVDLDITNLRAAVDASGRKTYPTQIWALATVVNRHPEFRM
ALDDQGNPGVWDVVDPAFTVFNPDRETFAGISARYTPDFDAFHSEAAELLSEYRNASTLFPQGAPRPRNVFDISSIPWTR
FTGFTLTIAPGWAHLAPIFTIGKFYEQEGRTMMPLALQIHHAAADGYHSARLVEELRQIIADPDWVRD

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 26171; Mature: 26040

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00100 CAT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAEHALLVVMATFEPLDLQQWPRREWFEHYLDRCPTYYSMTVDLDITNLRAAVDASGRK
CCCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHCCCCCC
TYPTQIWALATVVNRHPEFRMALDDQGNPGVWDVVDPAFTVFNPDRETFAGISARYTPDF
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCEEEEECCCHHHHCCCCCCCCCCH
DAFHSEAAELLSEYRNASTLFPQGAPRPRNVFDISSIPWTRFTGFTLTIAPGWAHLAPIF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEECCEEEEECCCHHHHHHHH
TIGKFYEQEGRTMMPLALQIHHAAADGYHSARLVEELRQIIADPDWVRD
HHHHHHHHCCCEECHHEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PAEHALLVVMATFEPLDLQQWPRREWFEHYLDRCPTYYSMTVDLDITNLRAAVDASGRK
CCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHCCCEEEEEEEEEHHHHHHHHCCCCCC
TYPTQIWALATVVNRHPEFRMALDDQGNPGVWDVVDPAFTVFNPDRETFAGISARYTPDF
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCEEEEECCCHHHHCCCCCCCCCCH
DAFHSEAAELLSEYRNASTLFPQGAPRPRNVFDISSIPWTRFTGFTLTIAPGWAHLAPIF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCEEECCEEEEECCCHHHHHHHH
TIGKFYEQEGRTMMPLALQIHHAAADGYHSARLVEELRQIIADPDWVRD
HHHHHHHHCCCEECHHEEEEEHHHCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2697637 [H]