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The map label for this gene is hemY [H]

Identifier: 169630068

GI number: 169630068

Start: 3045028

End: 3046404

Strand: Reverse

Name: hemY [H]

Synonym: MAB_2985c

Alternate gene names: 169630068

Gene position: 3046404-3045028 (Counterclockwise)

Preceding gene: 169630069

Following gene: 169630067

Centisome position: 60.12

GC content: 69.72

Gene sequence:

>1377_bases
GTGACGCCGCAGCCGTCGGGTTCTCCCTCCATTGCCATTGTGGGGGGCGGTATTTCGGGCCTGACGGCGGCATATCGGCT
CCGCCGCGAACTTGGTGATGACGCCCGCATCAGCCTCTACGACCCGGCCGGGCAGTTGGGCGGCATCCTGCGCACCATCA
CCCTGGGTGAACACCGGATCGACATCGGCGCCGAGGCCTTCATCACCCGGCGCCCGGAGGTTCTCGACCTGCTGGATGAA
CTGGGGCTGGCCGACCGCACGCTCGACACCACCGGCGCGCGGCCGCTGATCTACGCCGGCGGCGGCTTGCATCCGCTGCC
CGCGAGGACGGTGAACGGCATTCCGGCTTCGGCGTCGTCGGTGGTGGGGCTCGTCGACGAGGAAACCGTTGCCCGCATCG
ACAGTGAACCCCAGCGCGACATGCATTGGACCGTCGGAGCCGAACCGACCGTCGCTGACCTTGTCGCCCTGCGATTCGGG
CCGCAGGTCGTCGCCCGGCTGGTCGATCCGTTGCTCGGTGGCGTGTATGCGGGCTCGGCCGCGACGACGGGTCTGCGTAC
GGCAGCCCCCGGCATTGCCCGGGCACTCGACGAGGGAGCGGGCAGTCTGTTGGCCGCGGCCCGGCAGGCGTTGCCACCGA
TCTCCGACAGCGGCATTTTCGGTGCTGTTGACGGCGGCTATGCAGTGCTGGTGGAGGAGCTCTGGAGCCGTGCGCGGGCC
GAACATGTGCAGGTCGCGGTGACCGGCATCGAACGTGACGGCGCGGGCTGGGCGGTCACTGGCGAGGGCGGACTGACGGA
CGCCGTCGATGCCGTCATCGTGGCGGTGCCGGCACCCCGCGCGGCCGCAATTCTTGAGGCGGTGGCCCCTGAGTCGGCGG
CCGCCGCACGCACCATCCCGGTGGCCTCGTCGGTCGTCGTGGCGCTGACGCTGCCCGGCGACGCCCCGATACCCGCCAAT
TCGGGGGTGCTCGTCGCGTCGGGAGAAGCCTTGCATACCAAGGCCATAACGTTCTCGACCAGTAAGTGGGGGTTGCGCGG
GCGGAGTACCCAGGTGGTGCGACTTTCCTATGGACGCTTCGGTGACACGGTGGCGCGCGCTACCACCGACGAGCAGCTGC
GACACTGGGCCGTTGCCGATCTGGAGGCGGTGTTGGGCGCCGGCATCGTCCCGGTCAACTCGGCGGTGGCCCGCTGGATC
GATGCCATGCCGCAGTACGGGCCGGGCCACGCTGAAGTCGTCGACGCCATCCGTTCCGGATTGCCGTCCGGAATCGCGGT
GGCCGGCTCGTACCTGGATGGGATAGGGGTGCCGGCTTGTGTGGCCTCCGCCTCGCAAGCCGCGCAGGCCAGCGTGGCAC
GATGGAGGCATGGCTAG

Upstream 100 bases:

>100_bases
ATCTTCAATCTGGGGCATGGCGTGCTGCCGGATACCGATCCGGCGGTACTGACCGATGCGGCGGCGCTGGTGCATTCGTT
GTGATGTGTGAGCTGGCCAA

Downstream 100 bases:

>100_bases
CCTCGATTTCGACACCCTCAACTCCACCATCCGCTACCTGATGTTCTCGGTGTTCCAGGTACGCGACGGAGGTCTGGGCG
ACGACCGTGACGGCGTCGCC

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRIDIGAEAFITRRPEVLDLLDE
LGLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASSVVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFG
PQVVARLVDPLLGGVYAGSAATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARA
EHVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIPVASSVVVALTLPGDAPIPAN
SGVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRFGDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWI
DAMPQYGPGHAEVVDAIRSGLPSGIAVAGSYLDGIGVPACVASASQAAQASVARWRHG

Sequences:

>Translated_458_residues
MTPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRIDIGAEAFITRRPEVLDLLDE
LGLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASSVVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFG
PQVVARLVDPLLGGVYAGSAATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARA
EHVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIPVASSVVVALTLPGDAPIPAN
SGVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRFGDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWI
DAMPQYGPGHAEVVDAIRSGLPSGIAVAGSYLDGIGVPACVASASQAAQASVARWRHG
>Mature_457_residues
TPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRIDIGAEAFITRRPEVLDLLDEL
GLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASSVVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFGP
QVVARLVDPLLGGVYAGSAATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARAE
HVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIPVASSVVVALTLPGDAPIPANS
GVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRFGDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWID
AMPQYGPGHAEVVDAIRSGLPSGIAVAGSYLDGIGVPACVASASQAAQASVARWRHG

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=484, Percent_Identity=26.6528925619835, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4506001, Length=484, Percent_Identity=26.6528925619835, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 46693; Mature: 46562

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRI
CCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCHHHCHHHHEEEECCEEE
DIGAEAFITRRPEVLDLLDELGLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASS
CCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHH
VVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFGPQVVARLVDPLLGGVYAGSA
EEEECCHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
ATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARA
HHCCCHHCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
EHVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIP
CEEEEEEEEEEECCCCEEEECCCCCHHHHCEEEEEECCCHHHHHHHHHCCCHHHHHEECC
VASSVVVALTLPGDAPIPANSGVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRF
CCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
GDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWIDAMPQYGPGHAEVVDAIRSG
CCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LPSGIAVAGSYLDGIGVPACVASASQAAQASVARWRHG
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRI
CCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCHHHCHHHHEEEECCEEE
DIGAEAFITRRPEVLDLLDELGLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASS
CCCCHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHH
VVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFGPQVVARLVDPLLGGVYAGSA
EEEECCHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCH
ATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARA
HHCCCHHCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHH
EHVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIP
CEEEEEEEEEEECCCCEEEECCCCCHHHHCEEEEEECCCHHHHHHHHHCCCHHHHHEECC
VASSVVVALTLPGDAPIPANSGVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRF
CCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCCEEEEEECCCC
GDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWIDAMPQYGPGHAEVVDAIRSG
CCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
LPSGIAVAGSYLDGIGVPACVASASQAAQASVARWRHG
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]