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The map label for this gene is ubiB [C]

Identifier: 169630052

GI number: 169630052

Start: 3029336

End: 3030706

Strand: Direct

Name: ubiB [C]

Synonym: MAB_2969

Alternate gene names: 169630052

Gene position: 3029336-3030706 (Clockwise)

Preceding gene: 169630051

Following gene: 169630055

Centisome position: 59.78

GC content: 63.68

Gene sequence:

>1371_bases
ATGAGCGACCGAGTCCCCTTGGCGCGCATCAACCGTGGCCGCGCACTGGGAAAGCTGGCCGCCGGGCAGGCCGTACGGAC
CGCGAGCAGTCGCCTCTCCATGATCGGGCGATCCGAACAAGCGCGCGCGCTGCTAGCCGAACGATCCACACTGCAGGCAG
CAGACCAGCTGGTGACCGTCCTGGGCAGTCTCAAGGGCTCGGCGATGAAACTCGGCCAACTGCTCTCGATGCTCGAAGTG
GATATGGTGCCGGAGGCCCACCGCGAACGATTCCGGCAGAAGCTGGCCCGGTTGCGCGATCAGGCCCCACGTGAACCGTT
CTCGGTGATGCGCCCCATCATCGAATCTAACCTCGGCGCGCTGTCGAAGAACTTCCGCGACTTCGACGAAACGCCCGTCG
CCGCCGCTTCCATCGGCCAGGTCTACCGCGCCGTCCTGCTCGACGGGCGCGAGGTGGCGGTCAAGGTCAAGTACCCGGGC
GTGGACGAAGCCGTCCGCGCCGATATGCAGAACCTCGCGCTGTTCACCAAGTTTTGGCGCAAAGCGCTACCCACGCTATC
CAATTCGGCATTCATGGACGAGATATCCATGAACCTGGAAAGCGAACTCGACTATCCCCGGGAAGCGCGCACCCAGCACG
AGATCGCCGAGCGCTACCGTGGGCACCCCTTCATCGTCGTTCCCGACTGTGTCCCCGAACTGTGCACGTCGCAGATTCTG
GTGACGGAATTCCTTGATGGCCAAGCGTTCCCCTACATGCAGACACTTCCCGAGGATGAGCGTAACCGCATCGGAGAGCT
GATCTTCCGCTTCTACATCGGATCACTGTTCCAGGACAATGACTTCTGCGGTGACCCCCATCCGGGCAACATCCTGCTCG
CCGCCGATGGGACCGTCGGGTTCGTGGATTTCGGGCTGTACAACCGCATGAATCCCGAACATGTGGACTTCGAGCGCCAC
ATCATGCGGGCCGCCACCGAGGGCCGCGCCCAGGACATGTACGACGCGATGGTCGCGCGCGGAATCATCGATCCCCAGGC
CGGCGTCAGCCCCCAAGACTGCCTGGAGTACTGCCATGCGGCATCTGGGTGGAACCTCGTCGACGAGGACATGACCATCA
CCCCGGAGATCGCCTCCAGCGCCATGATTCTCGCGGTAGACCCACGGTCCAGCGAGTTCGCCGGTATGCGCCGCCAGAAC
CTGCCGCCGGAGCACATCTTCTCCCGTCGCGCCGACTTCTACACCTTCGGCGTGCTGGGCCAGCTGAATGTGACGGGTAA
TTGGCATCGCATAGCCCGCGAATGGATCTACGGTGAGCCTCCCGCCACCGAGCTCGGAATCGCCATCGCGCAGTGGCGCG
CGTGCCGCTAG

Upstream 100 bases:

>100_bases
TGTCGGGCCTTGCCGCGTCGATCGCCGAATTCAACGGACTCACCCTCGATCCCGATCAGCCGCTACATCTGGCATTCACC
CGGATCCAGGGTGGAGCCTC

Downstream 100 bases:

>100_bases
CGCAGCAATCCGTCGAGAGCGCGACCGAACATCCACTGACCGCCGATCTTGGCTAACGGATCGAAGATCGCAGGCACACC
ACGCACCCTCACGTCCTCGG

Product: putative ATP-binding protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTVLGSLKGSAMKLGQLLSMLEV
DMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGALSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPG
VDEAVRADMQNLALFTKFWRKALPTLSNSAFMDEISMNLESELDYPREARTQHEIAERYRGHPFIVVPDCVPELCTSQIL
VTEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVGFVDFGLYNRMNPEHVDFERH
IMRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCHAASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQN
LPPEHIFSRRADFYTFGVLGQLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR

Sequences:

>Translated_456_residues
MSDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTVLGSLKGSAMKLGQLLSMLEV
DMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGALSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPG
VDEAVRADMQNLALFTKFWRKALPTLSNSAFMDEISMNLESELDYPREARTQHEIAERYRGHPFIVVPDCVPELCTSQIL
VTEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVGFVDFGLYNRMNPEHVDFERH
IMRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCHAASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQN
LPPEHIFSRRADFYTFGVLGQLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR
>Mature_455_residues
SDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTVLGSLKGSAMKLGQLLSMLEVD
MVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGALSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPGV
DEAVRADMQNLALFTKFWRKALPTLSNSAFMDEISMNLESELDYPREARTQHEIAERYRGHPFIVVPDCVPELCTSQILV
TEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVGFVDFGLYNRMNPEHVDFERHI
MRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCHAASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQNL
PPEHIFSRRADFYTFGVLGQLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=334, Percent_Identity=31.437125748503, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI27363457, Length=278, Percent_Identity=32.3741007194245, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI40254938, Length=319, Percent_Identity=28.5266457680251, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI217416386, Length=235, Percent_Identity=33.6170212765957, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI217035081, Length=202, Percent_Identity=31.6831683168317, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI41393593, Length=264, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI2367309, Length=273, Percent_Identity=26.007326007326, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI32565180, Length=458, Percent_Identity=27.292576419214, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17559152, Length=268, Percent_Identity=30.9701492537313, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321319, Length=360, Percent_Identity=28.0555555555556, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18859849, Length=283, Percent_Identity=30.7420494699647, Blast_Score=124, Evalue=9e-29,
Organism=Drosophila melanogaster, GI22024280, Length=274, Percent_Identity=29.5620437956204, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24662575, Length=273, Percent_Identity=23.4432234432234, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 51110; Mature: 50979

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTV
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LGSLKGSAMKLGQLLSMLEVDMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGA
HHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPGVDEAVRADMQNLALFTKFWR
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
KALPTLSNSAFMDEISMNLESELDYPREARTQHEIAERYRGHPFIVVPDCVPELCTSQIL
HHCCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
VTEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVG
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEE
FVDFGLYNRMNPEHVDFERHIMRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCHA
EEEHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
ASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQNLPPEHIFSRRADFYTFGVLG
CCCCCEECCCCEECHHHCCCEEEEEECCCCCHHHCCHHCCCCHHHHHHCCCCEEEEEEEE
QLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR
EEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDRVPLARINRGRALGKLAAGQAVRTASSRLSMIGRSEQARALLAERSTLQAADQLVTV
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LGSLKGSAMKLGQLLSMLEVDMVPEAHRERFRQKLARLRDQAPREPFSVMRPIIESNLGA
HHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LSKNFRDFDETPVAAASIGQVYRAVLLDGREVAVKVKYPGVDEAVRADMQNLALFTKFWR
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHH
KALPTLSNSAFMDEISMNLESELDYPREARTQHEIAERYRGHPFIVVPDCVPELCTSQIL
HHCCCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHH
VTEFLDGQAFPYMQTLPEDERNRIGELIFRFYIGSLFQDNDFCGDPHPGNILLAADGTVG
HHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEE
FVDFGLYNRMNPEHVDFERHIMRAATEGRAQDMYDAMVARGIIDPQAGVSPQDCLEYCHA
EEEHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
ASGWNLVDEDMTITPEIASSAMILAVDPRSSEFAGMRRQNLPPEHIFSRRADFYTFGVLG
CCCCCEECCCCEECHHHCCCEEEEEECCCCCHHHCCHHCCCCHHHHHHCCCCEEEEEEEE
QLNVTGNWHRIAREWIYGEPPATELGIAIAQWRACR
EEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]