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The map label for this gene is paaJ [C]

Identifier: 169630034

GI number: 169630034

Start: 3006812

End: 3008017

Strand: Reverse

Name: paaJ [C]

Synonym: MAB_2951c

Alternate gene names: 169630034

Gene position: 3008017-3006812 (Counterclockwise)

Preceding gene: 169630035

Following gene: 169630033

Centisome position: 59.36

GC content: 60.45

Gene sequence:

>1206_bases
ATGGCAAACAGGGTTTACGTCGTCGGGGTGGGGATGACGAAGTTTGAGAAACCGGGGCGTCGGCTCAATGACGATGGATC
GGCGTGGGACTACCCCGATATGGCACGAGAGTCGGGGACCAAGGCGCTCGCGGATGCCGGCATTGGGTACGACCTGGTCG
AGCAGGCTTATGTCGGCTATGTCTACGGCGAATCGACATCCGGCCAGCGTGCGGTCTACGAGTTGGGTATGAGCGGTATC
CCGGTAGTCAACGTGAACAACAACTGCTCGACGGGATCGACTGCGCTTTATCTTGCGGCGCAATCGATCCGGGGCGGTTT
GGCGGACTGTGCGTTGGCGCTCGGCTTCGAGAAGATGAATCCCGGCTCGCTGGGCGCAATGTACGATGATCGTGCACAGC
CGATGGAGAAGCACATCCTGGCGCTCGCCGAGATTTCTGAGGTGTTGTTCCCGCCGGCGTCGTGGATGTTCGGCGCGGCG
GGGCGCGAGCATATGCAGCAATACGGTTCCACTGCTGAGCATTTCGCCAAGATTGGCCACAAGAACCACAAGCACTCGGT
CAACAACCCGTATGCACAGTTCCAGGACGAATACACCCTCGACGACATCCTGAACTCGCGGATGATCTATGACCCGTTGA
CCAAGCTGCAATGCTCACCGACCTCTGATGGTTCGGGGGCAGCGATCCTGGCATCCGAGGCTTTCGTCGATAGGCATGGA
TTGGCAAGCCAGGCAGTGGAGATCGTAGGGCAGGCGATGACCACAGATTTCCAGAACAGCTTCGACGGCACCTGCAAGGC
GATTATCGGTTACCACATGAATGTGTCGGCCGCGAGGCAGGTATACGACCAATCAGGCTTGGGCGCAGAGGATTTCCAAG
TCATCGAGCTGCACGATTGCTTCAGTGCCAACGAATTCCTGTTGTACGAGGCGCTGGGCCTGTGCGGCGAGGGTGAGGCC
GGGAAGCTGATCGACAACGGTGACACCACATACGGCGGGCGTTGGGTGGTCAACCCCTCGGGTGGGTTGATATCGAAGGG
GCATCCGTTGGGCGCCACGGGATTAGCGCAGTGTGCCGAGCTGACCTGGCAGTTGCGCGGTGCGGCGGACAAGCGCCAGG
TAGATCGCGTGGACGCGGCGCTGCAGCACAACATAGGGCTCGGCGGTGCGGCGGTAATCACCGCGTATCAGCGCGCCGAG
CGCTGA

Upstream 100 bases:

>100_bases
TTCAATAAACATGGTTGACCTGCATAGATAGTGGGCTTGTCAGGATACAATCTGGTGTGTATGTTTCTTCGAGACGGGAA
AGCCTCCTGAAGGGAATGTG

Downstream 100 bases:

>100_bases
ATCAAACAACCACAAATTCACCAACAGATCACCTAAGGAGTTAAACAATGGGACACATCGAAGCCACCAAGAATCTCTCG
GCCAGCCCGGATGCGCTGTG

Product: lipid-transfer protein

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MANRVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADAGIGYDLVEQAYVGYVYGESTSGQRAVYELGMSGI
PVVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDDRAQPMEKHILALAEISEVLFPPASWMFGAA
GREHMQQYGSTAEHFAKIGHKNHKHSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTSDGSGAAILASEAFVDRHG
LASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMNVSAARQVYDQSGLGAEDFQVIELHDCFSANEFLLYEALGLCGEGEA
GKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGAADKRQVDRVDAALQHNIGLGGAAVITAYQRAE
R

Sequences:

>Translated_401_residues
MANRVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADAGIGYDLVEQAYVGYVYGESTSGQRAVYELGMSGI
PVVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDDRAQPMEKHILALAEISEVLFPPASWMFGAA
GREHMQQYGSTAEHFAKIGHKNHKHSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTSDGSGAAILASEAFVDRHG
LASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMNVSAARQVYDQSGLGAEDFQVIELHDCFSANEFLLYEALGLCGEGEA
GKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGAADKRQVDRVDAALQHNIGLGGAAVITAYQRAE
R
>Mature_400_residues
ANRVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADAGIGYDLVEQAYVGYVYGESTSGQRAVYELGMSGIP
VVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMNPGSLGAMYDDRAQPMEKHILALAEISEVLFPPASWMFGAAG
REHMQQYGSTAEHFAKIGHKNHKHSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTSDGSGAAILASEAFVDRHGL
ASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMNVSAARQVYDQSGLGAEDFQVIELHDCFSANEFLLYEALGLCGEGEAG
KLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAELTWQLRGAADKRQVDRVDAALQHNIGLGGAAVITAYQRAER

Specific function: Thiolytic Cleavage Of Beta-Ketoadipyl-CoA To Succinate And Acetyl-CoA (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19923233, Length=397, Percent_Identity=62.2166246851385, Blast_Score=496, Evalue=1e-140,
Organism=Homo sapiens, GI302344760, Length=397, Percent_Identity=58.1863979848867, Blast_Score=454, Evalue=1e-128,
Organism=Homo sapiens, GI302344767, Length=323, Percent_Identity=62.2291021671827, Blast_Score=414, Evalue=1e-116,
Organism=Homo sapiens, GI302344762, Length=396, Percent_Identity=54.7979797979798, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI55956775, Length=358, Percent_Identity=52.7932960893855, Blast_Score=352, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI17537653, Length=387, Percent_Identity=50.6459948320413, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24585051, Length=398, Percent_Identity=64.572864321608, Blast_Score=519, Evalue=1e-147,
Organism=Drosophila melanogaster, GI19921506, Length=398, Percent_Identity=63.8190954773869, Blast_Score=518, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 43019; Mature: 42887

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADAGIGYDLVEQAYVGY
CCCEEEEEECCHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCHHHHHHHHEEE
VYGESTSGQRAVYELGMSGIPVVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMN
EECCCCCCCHHHHHHCCCCCEEEECCCCCCCCCEEEEEEHHHHCCCHHHHHHHHCCCCCC
PGSLGAMYDDRAQPMEKHILALAEISEVLFPPASWMFGAAGREHMQQYGSTAEHFAKIGH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCHHHHHHHHCC
KNHKHSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTSDGSGAAILASEAFVDRHG
CCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHCEECCCCCCCCCEEEEHHHHHHHCC
LASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMNVSAARQVYDQSGLGAEDFQVIELHDC
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCC
FSANEFLLYEALGLCGEGEAGKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE
CCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LTWQLRGAADKRQVDRVDAALQHNIGLGGAAVITAYQRAER
HHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ANRVYVVGVGMTKFEKPGRRLNDDGSAWDYPDMARESGTKALADAGIGYDLVEQAYVGY
CCEEEEEECCHHHHCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHCCCCHHHHHHHHEEE
VYGESTSGQRAVYELGMSGIPVVNVNNNCSTGSTALYLAAQSIRGGLADCALALGFEKMN
EECCCCCCCHHHHHHCCCCCEEEECCCCCCCCCEEEEEEHHHHCCCHHHHHHHHCCCCCC
PGSLGAMYDDRAQPMEKHILALAEISEVLFPPASWMFGAAGREHMQQYGSTAEHFAKIGH
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCCHHHHHHHHCC
KNHKHSVNNPYAQFQDEYTLDDILNSRMIYDPLTKLQCSPTSDGSGAAILASEAFVDRHG
CCCCCCCCCCHHHHCCCCCHHHHHCCCCCCCCHHHCEECCCCCCCCCEEEEHHHHHHHCC
LASQAVEIVGQAMTTDFQNSFDGTCKAIIGYHMNVSAARQVYDQSGLGAEDFQVIELHDC
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEEECCC
FSANEFLLYEALGLCGEGEAGKLIDNGDTTYGGRWVVNPSGGLISKGHPLGATGLAQCAE
CCCCHHHHHHHHCCCCCCCCCCEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
LTWQLRGAADKRQVDRVDAALQHNIGLGGAAVITAYQRAER
HHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]