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The map label for this gene is pucA [H]

Identifier: 169630007

GI number: 169630007

Start: 2977292

End: 2978365

Strand: Reverse

Name: pucA [H]

Synonym: MAB_2924c

Alternate gene names: 169630007

Gene position: 2978365-2977292 (Counterclockwise)

Preceding gene: 169630008

Following gene: 169630006

Centisome position: 58.78

GC content: 68.62

Gene sequence:

>1074_bases
ATGAAGGACATACTCAGGGATCTGATCGCGGTACTCGAAGGCGGTGGCACCGCCGCGTTGGCGCGTGTGGTGGAGGTCAG
TGGCGCGGTGCCGCGTGAGCCCGGGGCGGCGATGATCGTGCCAGCCGACGGGCCGGTCGTCGGGTCACTGTCCGGTGGGT
GCGTGGAGGCGGCGGTCATCGAGACGGCACGCGAGGTGCTGGCCATCGGGCTCTGTGTCAGTGAGCGATTCGGTATTGAC
GACGGGATCGCGCCGGGCCTTACCTGCGGCGGCGAGATCGAAGTCGTCACCGAACATATTGGCGCCGAGCGGTTTCCGTT
GCTTCGGGAACTGCGGTCGGCGCTCGTGGCGGGGGAGCCGATGGGTTTGGTGAGCACGCTGTCGGGGATTCCCGATTGGG
CACTGGTGCGGGCCGGGGAGCCGGCGCCGTGGCCGCAGATCGAGGGCGACATCGTGTCGTTGATACGTGCGGGCCGCAGC
GCGGTGGCAGGTGCCGATCGCTGCGAACCCGATCAATCCGACCTGCCCCGGGTGTTTGTGCAGGCATTCGCGGCGCCGCC
ACGCATGATCCTGGCGGGGGCCAACGCTTTTGTACGCGCCCTGAGCCGTACCGGCAGCCAGCTGGGCTACCGGGTGACGG
TGGTCGATGCCCGCGAAGTGTTCGCGACGCCCGCGCACTTTCCGTATGCGGATGAGGTGGTCGTCGACTGGCCCCACCGG
TACCTGCGTGCCGAGGCGGCAGGCGGTCGCGTCGATGCGCGCACCGTGGTGTGCGTTCTGACACATGATCCCAAGTTCGA
CGTGCCGATGCTGGCGGCTGCCCTGACCGTGGCGCCGGTGGCCTTTGTCGGCGCGCTGGGCTCGCGGCGCACGCACACCG
ATCGGATGGCGCGTCTGCGCGAGCAGGGCGTCACCGACGATCAGCTGGGGCGGCTGCGTAGCCCGCTGGGCCTGGACCTC
AATGCCCGGACTCCCGAGGAGACCGCGATATCGATTGCGGCACAGATCATTGCCGAAACATCGGGTGGCTCTGGGCGGCC
GTTGAGTGACATCGACGGGCCGATCCACCGGTAG

Upstream 100 bases:

>100_bases
ACGCCATCCGCGATGCTGTCGGCGTCCGGGTGTACCGCCTGCCGATGAACGCGGCGCGCGTGTGGCGGGTGATCAACGAC
TCCGGGGGCGGTGAGTCGTC

Downstream 100 bases:

>100_bases
GGGCTGCGGTGTACCTGAAGGCATGTCTGAACGGAGTCCGGCGCAAGGACCAGCATCCCGCGATTCCCTGCACGGCCGAG
GAGATCGCGGCGGATGCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: XDHase subunit A [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPVVGSLSGGCVEAAVIETAREVLAIGLCVSERFGID
DGIAPGLTCGGEIEVVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSGIPDWALVRAGEPAPWPQIEGDIVSLIRAGRS
AVAGADRCEPDQSDLPRVFVQAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYADEVVVDWPHR
YLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVAFVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDL
NARTPEETAISIAAQIIAETSGGSGRPLSDIDGPIHR

Sequences:

>Translated_357_residues
MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPVVGSLSGGCVEAAVIETAREVLAIGLCVSERFGID
DGIAPGLTCGGEIEVVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSGIPDWALVRAGEPAPWPQIEGDIVSLIRAGRS
AVAGADRCEPDQSDLPRVFVQAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYADEVVVDWPHR
YLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVAFVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDL
NARTPEETAISIAAQIIAETSGGSGRPLSDIDGPIHR
>Mature_357_residues
MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPVVGSLSGGCVEAAVIETAREVLAIGLCVSERFGID
DGIAPGLTCGGEIEVVTEHIGAERFPLLRELRSALVAGEPMGLVSTLSGIPDWALVRAGEPAPWPQIEGDIVSLIRAGRS
AVAGADRCEPDQSDLPRVFVQAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYADEVVVDWPHR
YLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVAFVGALGSRRTHTDRMARLREQGVTDDQLGRLRSPLGLDL
NARTPEETAISIAAQIIAETSGGSGRPLSDIDGPIHR

Specific function: Oxidizes hypoxanthine and xanthine to uric acid. PucA subunit could exert a molybdenum cofactor recruiting function [H]

COG id: COG1975

COG function: function code O; Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789240, Length=193, Percent_Identity=30.0518134715026, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786477, Length=91, Percent_Identity=36.2637362637363, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003777 [H]

Pfam domain/function: PF02625 XdhC_CoxI [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 37428; Mature: 37428

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPVVGSLSGGCVEAAVI
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHH
ETAREVLAIGLCVSERFGIDDGIAPGLTCGGEIEVVTEHIGAERFPLLRELRSALVAGEP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCC
MGLVSTLSGIPDWALVRAGEPAPWPQIEGDIVSLIRAGRSAVAGADRCEPDQSDLPRVFV
CHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHH
QAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYADEVVVDWPHR
HHHCCCCCEEEECHHHHHHHHHHCCHHCCEEEEEEEHHHHHCCCCCCCCCCCEEEECCHH
YLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVAFVGALGSRRTHTDRMARLR
HHHHHCCCCCEECEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EQGVTDDQLGRLRSPLGLDLNARTPEETAISIAAQIIAETSGGSGRPLSDIDGPIHR
HCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MKDILRDLIAVLEGGGTAALARVVEVSGAVPREPGAAMIVPADGPVVGSLSGGCVEAAVI
CHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCCCCHHHHHHH
ETAREVLAIGLCVSERFGIDDGIAPGLTCGGEIEVVTEHIGAERFPLLRELRSALVAGEP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCC
MGLVSTLSGIPDWALVRAGEPAPWPQIEGDIVSLIRAGRSAVAGADRCEPDQSDLPRVFV
CHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHH
QAFAAPPRMILAGANAFVRALSRTGSQLGYRVTVVDAREVFATPAHFPYADEVVVDWPHR
HHHCCCCCEEEECHHHHHHHHHHCCHHCCEEEEEEEHHHHHCCCCCCCCCCCEEEECCHH
YLRAEAAGGRVDARTVVCVLTHDPKFDVPMLAAALTVAPVAFVGALGSRRTHTDRMARLR
HHHHHCCCCCEECEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EQGVTDDQLGRLRSPLGLDLNARTPEETAISIAAQIIAETSGGSGRPLSDIDGPIHR
HCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]