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The map label for this gene is aroE [H]

Identifier: 169629932

GI number: 169629932

Start: 2896563

End: 2897378

Strand: Reverse

Name: aroE [H]

Synonym: MAB_2848c

Alternate gene names: 169629932

Gene position: 2897378-2896563 (Counterclockwise)

Preceding gene: 169629933

Following gene: 169629931

Centisome position: 57.18

GC content: 69.73

Gene sequence:

>816_bases
GTGCTCGCTGAGATTCGCCGCGCCGCGGTCCTGGGTTCACCGATCGGGCATTCGCGCTCACCGGATTTGCACGTGGCGGC
CTACCGCGCGCTGGGCCTGACCGGGTGGACCTACGAACGAATCGAGTGCACGGCCGAGCAGCTGCCCGATGTGGTCGGCG
GTGCCGGTCCTGAATGGGTGGGCTTCTCGGTAACCATGCCGGGCAAGTTCGCCGCATTGCGGTTCGCGTCGACTTCGACC
GAGCGTGCGCGCTCGATCGGCGCCGCCAATACGCTGGTGCGCTCCGGTGATGGTTGGCATGCCGACAACACCGACGTCGA
CGGGGTTTCGGGGGCGTTGGCCGGCGCCGGCATCGACCCGGCGGGACAATCCGCGGTGATTGTGGGGGCCGGTGGAACCG
CCCGCCCGGCGATCGTTGCGCTTGCCGCGATGGGCGTGCGCGCTCTCACGGTGGTGGCCCGTGACGCGGGCCGGGCACAG
GGCGTACTCGAGCTTGCCGAGCACCTGGGCCTGCGTGCCTCGGTGCTCAGTTTTACGGACGCGGAGCTTTCTTCGGTGTG
TCAGGCCGCGGGTGTGCTGGTCAGCACCGTGCCCGCGGAGGCCGCTGCTCCCTATGCGCGGTCATTGGCGGCGGCACCGG
CGATTCTCGATGTCATCTACCATCCGTGGCCCACCACGCTGGCCGCCGCCGCGCAGCGCCGCGGGGCAGTGGTGGTCGGC
GGGCTGGACATGTTGCTGAACCAGGCGTTTACCCAGGTGGAACTCTTCACCGGGCTGTCCGCTCCACGTGCTGCCATGGC
CGCGGCCCTGCACTGA

Upstream 100 bases:

>100_bases
TTCGTCACCATTGACGCCGAGGGGACCACGCTGTTCACCGCCGACTACAACGAGCACTTGGCGAATATCGAGCTCGCCAA
GAAGAACGGCATCCTGGACA

Downstream 100 bases:

>100_bases
TCACCCGGCTCCACCCTGCTCGCGGCATGGGGGCTTGCTTCTCACCTGGTCTTACGAAATTTGTGGGACTTTCGGTCCCA
TCAGCTCTTGCGTGGGATGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLAEIRRAAVLGSPIGHSRSPDLHVAAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWVGFSVTMPGKFAALRFASTST
ERARSIGAANTLVRSGDGWHADNTDVDGVSGALAGAGIDPAGQSAVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQ
GVLELAEHLGLRASVLSFTDAELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWPTTLAAAAQRRGAVVVG
GLDMLLNQAFTQVELFTGLSAPRAAMAAALH

Sequences:

>Translated_271_residues
MLAEIRRAAVLGSPIGHSRSPDLHVAAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWVGFSVTMPGKFAALRFASTST
ERARSIGAANTLVRSGDGWHADNTDVDGVSGALAGAGIDPAGQSAVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQ
GVLELAEHLGLRASVLSFTDAELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWPTTLAAAAQRRGAVVVG
GLDMLLNQAFTQVELFTGLSAPRAAMAAALH
>Mature_271_residues
MLAEIRRAAVLGSPIGHSRSPDLHVAAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWVGFSVTMPGKFAALRFASTST
ERARSIGAANTLVRSGDGWHADNTDVDGVSGALAGAGIDPAGQSAVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQ
GVLELAEHLGLRASVLSFTDAELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWPTTLAAAAQRRGAVVVG
GLDMLLNQAFTQVELFTGLSAPRAAMAAALH

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=274, Percent_Identity=27.7372262773723, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789675, Length=249, Percent_Identity=28.9156626506024, Blast_Score=68, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320332, Length=285, Percent_Identity=30.5263157894737, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27496; Mature: 27496

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEIRRAAVLGSPIGHSRSPDLHVAAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWV
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHCCCCCCCE
GFSVTMPGKFAALRFASTSTERARSIGAANTLVRSGDGWHADNTDVDGVSGALAGAGIDP
EEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCC
AGQSAVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQGVLELAEHLGLRASVLSFTD
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCH
AELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWPTTLAAAAQRRGAVVVG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEC
GLDMLLNQAFTQVELFTGLSAPRAAMAAALH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MLAEIRRAAVLGSPIGHSRSPDLHVAAYRALGLTGWTYERIECTAEQLPDVVGGAGPEWV
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHCCCCCCCE
GFSVTMPGKFAALRFASTSTERARSIGAANTLVRSGDGWHADNTDVDGVSGALAGAGIDP
EEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCC
AGQSAVIVGAGGTARPAIVALAAMGVRALTVVARDAGRAQGVLELAEHLGLRASVLSFTD
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHCH
AELSSVCQAAGVLVSTVPAEAAAPYARSLAAAPAILDVIYHPWPTTLAAAAQRRGAVVVG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEC
GLDMLLNQAFTQVELFTGLSAPRAAMAAALH
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA