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The map label for this gene is yebQ [C]

Identifier: 169629891

GI number: 169629891

Start: 2854903

End: 2856447

Strand: Direct

Name: yebQ [C]

Synonym: MAB_2807

Alternate gene names: 169629891

Gene position: 2854903-2856447 (Clockwise)

Preceding gene: 169629890

Following gene: 169629896

Centisome position: 56.34

GC content: 65.31

Gene sequence:

>1545_bases
GTGACGCACACAGCGACGGAGCCCGGCACTTCCCTGCCGCTGCGGCATCGCAGCATCGCGATAGGCGCCGGAAGTCTGGC
GGTCCTGTTGGGCGCCCTCGACACCTATGTCGTGGTCAGCGTCATCACCGACATCATGACCAGTGTCGGCATCGCACTGA
ACAACATCCAACAGGTCACCCCGATCGTGACGGGTTACCTGCTCGGGTACATCGCCGCGATGCCGCTGCTGGGACAGGCC
TCCGACCGATTCGGGCGACGGTTGATCCTGCAACTGGCCCTGGCCGGATTCGCGATTGGTTCCGTCATCACAGCGCTGTC
CACCGATCTGACGATGCTGGTCAGCGGCCGCGTCATTCAGGGTGTCGCGAGCGGTGCGCTGCTACCGGTCACGCTGGCGC
TGGGGGCCGATCTGTGGTCGCAGCGCAACCGTGCGACGGTTCTCGGCGGCATCGGTGCCGCGCAGGAGCTGGGCAGCGTG
CTGGGCCCGCTGTACGGCGTGCTGTGCGTCTGGCTGTTCGGCTCGTGGACGGCGATCTTCTGGGTCAACGTGCCGCTGGC
GATCATCGCCATCGTGCTGGTCCAATTCAGTGTTCCGGCACACCAGCACGACCCCGATCGCCCCAAGGTCGATGTCGTGG
GCGGCGCGCTGCTGGCCGTCGCCTTGGGCCTGCTGGTCGTGGGCCTGTACAGCCCCGACCCCAAGGTCTCCGCGTTACCT
GAGTGGGCCCTACCGGTTCTCAGCGGTTCCGGAGTCGCGTTCCTGGCGTTCATTCTCTGGGAATCGCGGGCCAAGACCCG
GCTTATCAAGCCCGAAGGCGTTCGCTTCGGGCCCTTCTTCGCGGCGTTGGCCGCATCACTGGCAGCCGGCGCCGCCCTGA
TGGTGACCCTTGTCAATATCGAGCTGCTCGGGCAGGGCGTCCTGCAGATGGACAAGGCCGACGCGGTGTTCCTGTTGTCC
AGGTTCCTCGTCGCCCTGCCGATCGGCGCGGTGATCGGCGGCTGGCTCGCGACGCGATTCGGCGACCGGATCATCGCGGT
GATCGGCATGCTCATCGCCGCGTTCGGGTACTACCTGATTTCCGGGTGGCCGGTCGACGTGTTGGCGGCCGTGCACAACT
TCGGCTTCTTCACTCTTCCCCGCCTCGACACGGACCTGGTAGTCGCCGGTATCGGCCTGGGTCTGGTGATCGGTCCACTG
TCTTCAGCCGCTCTACGCGTGGTGCCCGCTGCGCAGCACGGCATCGCGTCGGCACTCGTGGTGGTGGCCCGCATGACAGG
AATGCTCATCGGCATGGCCGCCCTCGGCGGCTGGGGCATTCACCGCTTCTATCAGAACTTCGATGCGCTGGCCGCAAAGG
AACCCAAGCCGACAGGAAAGCCGAATCTCCTTGAGTTGCAACAGCAGCTGCTGAATCGGAGCATCACCGCCTACAGCGAG
ATGTACAGCGAGATGTTCGCGATCACGGCGGTCGTCTGTGTCATCGCGGCGGTTATCGCGATATTCGTCGGCTCACACCG
GAAGTCGGGGCACGAGGCTCAGTAG

Upstream 100 bases:

>100_bases
ACGCGCTGACCAAGATCAGCGTCGACACCTCACCGGGCAACACGATTGAGATGTCGTTGTCCGACTGGGGCAAGCCCGTC
ACGGTCGACAAGCCCGCCCA

Downstream 100 bases:

>100_bases
TACGTCCGGACCCATCCGCTCGATCTGGTCGTACTCCCAACGCAGTGCCCGCGACAGGGTGGTAACGCCCACGTCCTCCA
CGGCGGGGACGTTGCCACCC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTHTATEPGTSLPLRHRSIAIGAGSLAVLLGALDTYVVVSVITDIMTSVGIALNNIQQVTPIVTGYLLGYIAAMPLLGQA
SDRFGRRLILQLALAGFAIGSVITALSTDLTMLVSGRVIQGVASGALLPVTLALGADLWSQRNRATVLGGIGAAQELGSV
LGPLYGVLCVWLFGSWTAIFWVNVPLAIIAIVLVQFSVPAHQHDPDRPKVDVVGGALLAVALGLLVVGLYSPDPKVSALP
EWALPVLSGSGVAFLAFILWESRAKTRLIKPEGVRFGPFFAALAASLAAGAALMVTLVNIELLGQGVLQMDKADAVFLLS
RFLVALPIGAVIGGWLATRFGDRIIAVIGMLIAAFGYYLISGWPVDVLAAVHNFGFFTLPRLDTDLVVAGIGLGLVIGPL
SSAALRVVPAAQHGIASALVVVARMTGMLIGMAALGGWGIHRFYQNFDALAAKEPKPTGKPNLLELQQQLLNRSITAYSE
MYSEMFAITAVVCVIAAVIAIFVGSHRKSGHEAQ

Sequences:

>Translated_514_residues
MTHTATEPGTSLPLRHRSIAIGAGSLAVLLGALDTYVVVSVITDIMTSVGIALNNIQQVTPIVTGYLLGYIAAMPLLGQA
SDRFGRRLILQLALAGFAIGSVITALSTDLTMLVSGRVIQGVASGALLPVTLALGADLWSQRNRATVLGGIGAAQELGSV
LGPLYGVLCVWLFGSWTAIFWVNVPLAIIAIVLVQFSVPAHQHDPDRPKVDVVGGALLAVALGLLVVGLYSPDPKVSALP
EWALPVLSGSGVAFLAFILWESRAKTRLIKPEGVRFGPFFAALAASLAAGAALMVTLVNIELLGQGVLQMDKADAVFLLS
RFLVALPIGAVIGGWLATRFGDRIIAVIGMLIAAFGYYLISGWPVDVLAAVHNFGFFTLPRLDTDLVVAGIGLGLVIGPL
SSAALRVVPAAQHGIASALVVVARMTGMLIGMAALGGWGIHRFYQNFDALAAKEPKPTGKPNLLELQQQLLNRSITAYSE
MYSEMFAITAVVCVIAAVIAIFVGSHRKSGHEAQ
>Mature_513_residues
THTATEPGTSLPLRHRSIAIGAGSLAVLLGALDTYVVVSVITDIMTSVGIALNNIQQVTPIVTGYLLGYIAAMPLLGQAS
DRFGRRLILQLALAGFAIGSVITALSTDLTMLVSGRVIQGVASGALLPVTLALGADLWSQRNRATVLGGIGAAQELGSVL
GPLYGVLCVWLFGSWTAIFWVNVPLAIIAIVLVQFSVPAHQHDPDRPKVDVVGGALLAVALGLLVVGLYSPDPKVSALPE
WALPVLSGSGVAFLAFILWESRAKTRLIKPEGVRFGPFFAALAASLAAGAALMVTLVNIELLGQGVLQMDKADAVFLLSR
FLVALPIGAVIGGWLATRFGDRIIAVIGMLIAAFGYYLISGWPVDVLAAVHNFGFFTLPRLDTDLVVAGIGLGLVIGPLS
SAALRVVPAAQHGIASALVVVARMTGMLIGMAALGGWGIHRFYQNFDALAAKEPKPTGKPNLLELQQQLLNRSITAYSEM
YSEMFAITAVVCVIAAVIAIFVGSHRKSGHEAQ

Specific function: Confers resistance to tetracycline and aminoglycosides such as streptomycin and gentamicin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=452, Percent_Identity=25.4424778761062, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790195, Length=350, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790146, Length=150, Percent_Identity=31.3333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789042, Length=412, Percent_Identity=22.8155339805825, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=322, Percent_Identity=27.9503105590062, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6325455, Length=158, Percent_Identity=24.6835443037975, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323735, Length=283, Percent_Identity=27.208480565371, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53771; Mature: 53640

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTATEPGTSLPLRHRSIAIGAGSLAVLLGALDTYVVVSVITDIMTSVGIALNNIQQVT
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIVTGYLLGYIAAMPLLGQASDRFGRRLILQLALAGFAIGSVITALSTDLTMLVSGRVIQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GVASGALLPVTLALGADLWSQRNRATVLGGIGAAQELGSVLGPLYGVLCVWLFGSWTAIF
HHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEH
WVNVPLAIIAIVLVQFSVPAHQHDPDRPKVDVVGGALLAVALGLLVVGLYSPDPKVSALP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EWALPVLSGSGVAFLAFILWESRAKTRLIKPEGVRFGPFFAALAASLAAGAALMVTLVNI
CHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLGQGVLQMDKADAVFLLSRFLVALPIGAVIGGWLATRFGDRIIAVIGMLIAAFGYYLI
HHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGWPVDVLAAVHNFGFFTLPRLDTDLVVAGIGLGLVIGPLSSAALRVVPAAQHGIASALV
CCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHH
VVARMTGMLIGMAALGGWGIHRFYQNFDALAAKEPKPTGKPNLLELQQQLLNRSITAYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MYSEMFAITAVVCVIAAVIAIFVGSHRKSGHEAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
THTATEPGTSLPLRHRSIAIGAGSLAVLLGALDTYVVVSVITDIMTSVGIALNNIQQVT
CCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PIVTGYLLGYIAAMPLLGQASDRFGRRLILQLALAGFAIGSVITALSTDLTMLVSGRVIQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GVASGALLPVTLALGADLWSQRNRATVLGGIGAAQELGSVLGPLYGVLCVWLFGSWTAIF
HHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEH
WVNVPLAIIAIVLVQFSVPAHQHDPDRPKVDVVGGALLAVALGLLVVGLYSPDPKVSALP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EWALPVLSGSGVAFLAFILWESRAKTRLIKPEGVRFGPFFAALAASLAAGAALMVTLVNI
CHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELLGQGVLQMDKADAVFLLSRFLVALPIGAVIGGWLATRFGDRIIAVIGMLIAAFGYYLI
HHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGWPVDVLAAVHNFGFFTLPRLDTDLVVAGIGLGLVIGPLSSAALRVVPAAQHGIASALV
CCCHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHEEEECCHHHHHHHHHH
VVARMTGMLIGMAALGGWGIHRFYQNFDALAAKEPKPTGKPNLLELQQQLLNRSITAYSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
MYSEMFAITAVVCVIAAVIAIFVGSHRKSGHEAQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]