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The map label for this gene is ggt [H]

Identifier: 169629872

GI number: 169629872

Start: 2835568

End: 2837511

Strand: Direct

Name: ggt [H]

Synonym: MAB_2788

Alternate gene names: 169629872

Gene position: 2835568-2837511 (Clockwise)

Preceding gene: 169629870

Following gene: 169629883

Centisome position: 55.96

GC content: 66.36

Gene sequence:

>1944_bases
GTGAGAGCCCTGACCAGAGCGCTAGCCATCGCCTCTATCGCCCTTCTGGCGTCCGCGGGCTGCGCCGGCGACATGACGAG
CAGGCCGGGCGGCGCGGCGGAACCATGCGGGATCACCGCAAACGGTGTTCCGATCACGAAAACCGCTGCCACTCAAGCGG
CTACCGAACGAAACATCTCCACCAATCCCGAAGTGGCCACCGGCTATCGGACCGGGATGACCGCGGTACGTACCGCGAGC
TATGCCGCCGCAACCGCAAACCCCCTGGCCACGCAGGCCGCGTGCAAGGTGCTGCGTGACGGAGGGTCCGCCGCCGATGC
CCTGGTTGCCGCCCAAGCCGTGCTCGGGCTGGTCGAGCCGCAATCCTCGGGCATCGGGGGCGGCGGCTTCCTCGTCTACT
ACGACGCCGCCAGCGGTGCGGTACAGACCTATGACGGTAGAGAAGTCGCCCCGGCCGCCGCGACCGAGAACTATCTACGC
TGGGTCGACGACGCAGACCGGACTGCACCCAGACCCGATGTGCGGTCGTCGGGCCGCTCGATCGGAGTGCCCGGAATCCT
GCGCATGCTCTACGACGTGCATGCCGAGCACGGAGCCGCACCCTGGCGCGAGTTGTTCACTCCGGCAGTTCAATTGGCAG
ACGACGGCTTCGAGATCAGCCCGCGCCTGGCCGCGGCGATCACCGATTCAGCGGCCAGTCTTGCCCTGGATCCAGAAGCC
GACCTCTACCTTCTCAACACCGATGGTTCGGCCAAACCCGCCGGAACCAAGATCACCAACCCGGCCTACGCAAAAACCCT
CGGCGCCGTTGCTGCCGACGGACCCGATGCCTTCTACCGGGGCGCCATCGCCGAAGCCATCGTGGCCGCGGCGGCGGACA
CCTCGTCGGGACGCACCCCGAGCCTGATGACCACCGCAGACCTATCTGGATACACCGCCAAGAGGCGGGCAGCGCTGTGC
ACCACCTACCGCGACCACGAGATCTGCGGTATGCCAGCGCCTTCCTCGGGAGGTATCGCGGTGGCCGCGACATTGGGCAT
CCTGCAGAACTTCCCGATGGCATCCTTCCGGCCCACCGATATCGATCTCGACGGCGGCAAGCCGACGGTTGACGGGGTGC
ACTACATCGCCGAGGCGGAACGGCTCGCCTATGCCGACCGCGACAAATACGTTGCCGACACAGATTTTGTTGCGCTACCA
GGTAATTCACCCGACACTCTGCTGAATCCGACGTACCTGGCCGGGCGGGCACGACTGATCTCCGGCGATACAACGATGGG
CGTCGCCAAGCCGGGCGAATTCAACATACCGGCATCCGCGGCGGTATCCACCCCCGAGCACGGCACCAGCCAGGTGACCG
TCGTCGACGCCCGGGGCAACGCGGCGTCGCTCACCACGACGGTGGAGTCAGCATTCGGTTCGTTCCACATGGTGGACGGG
TTCTTCCTCAACAATCAGCTCACCGACTTCTCGGCCGAGCCCGTGGGTAAAGACGGGCTCCCGGTCGCCAACCGGCTGCA
ACCAGGAAAACGCCCCCGTAGCTCGATGGCGCCCACCCTGGTTTTCGAACGCGCCGAATCCGGCAAGCGCGGCGCGTTGC
TCCTGGCACTCGGCTCGCCGGGCGGCTCGGTGATCATCCAGTTTGTTGTGAAAACCCTTGTCGGCATTCTGGACTGGGGC
CTCGATCCACAGCAGGCGGTGTCGATGGTGGACTTCGGCGCCAACAACTCCCCCAAGACCAATGTCGGCGGCGAACACCC
CAGTATCGATGCCCGCGACAACGGCGCCGACGACCCCTTGATCCAGCGGCTGCGCGCACGTGGCCACATCGTCGACGTCG
CCGATCAGTCCAGTGGCCTGTCCGCGCTGGTGCGCCGGGGACCGGGCTGGATCGGCGGCGCGGACCCTCGCCGCGAAGGA
CTGGTCATGGGCGACACCGGATAG

Upstream 100 bases:

>100_bases
GTCCGAATAATCCGGCTGTCTGGGGCGCGCCTCCGAACACGCGCGGAACCTATCACGTAGGTCGACCGCCCAGCCGACCA
TGGCATAACGTGATCACACT

Downstream 100 bases:

>100_bases
CGGCCGATCAGCCCAGCGACTCAAGCCCCGGGTCGTCGATCGCGGAGGCGCGCGAGGTGTCCTTGAGTTCCACGCCGGAG
CGGCCCAACTGAAGCGCTCC

Product: gamma-glutamyltranspeptidase (GgtB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MRALTRALAIASIALLASAGCAGDMTSRPGGAAEPCGITANGVPITKTAATQAATERNISTNPEVATGYRTGMTAVRTAS
YAAATANPLATQAACKVLRDGGSAADALVAAQAVLGLVEPQSSGIGGGGFLVYYDAASGAVQTYDGREVAPAAATENYLR
WVDDADRTAPRPDVRSSGRSIGVPGILRMLYDVHAEHGAAPWRELFTPAVQLADDGFEISPRLAAAITDSAASLALDPEA
DLYLLNTDGSAKPAGTKITNPAYAKTLGAVAADGPDAFYRGAIAEAIVAAAADTSSGRTPSLMTTADLSGYTAKRRAALC
TTYRDHEICGMPAPSSGGIAVAATLGILQNFPMASFRPTDIDLDGGKPTVDGVHYIAEAERLAYADRDKYVADTDFVALP
GNSPDTLLNPTYLAGRARLISGDTTMGVAKPGEFNIPASAAVSTPEHGTSQVTVVDARGNAASLTTTVESAFGSFHMVDG
FFLNNQLTDFSAEPVGKDGLPVANRLQPGKRPRSSMAPTLVFERAESGKRGALLLALGSPGGSVIIQFVVKTLVGILDWG
LDPQQAVSMVDFGANNSPKTNVGGEHPSIDARDNGADDPLIQRLRARGHIVDVADQSSGLSALVRRGPGWIGGADPRREG
LVMGDTG

Sequences:

>Translated_647_residues
MRALTRALAIASIALLASAGCAGDMTSRPGGAAEPCGITANGVPITKTAATQAATERNISTNPEVATGYRTGMTAVRTAS
YAAATANPLATQAACKVLRDGGSAADALVAAQAVLGLVEPQSSGIGGGGFLVYYDAASGAVQTYDGREVAPAAATENYLR
WVDDADRTAPRPDVRSSGRSIGVPGILRMLYDVHAEHGAAPWRELFTPAVQLADDGFEISPRLAAAITDSAASLALDPEA
DLYLLNTDGSAKPAGTKITNPAYAKTLGAVAADGPDAFYRGAIAEAIVAAAADTSSGRTPSLMTTADLSGYTAKRRAALC
TTYRDHEICGMPAPSSGGIAVAATLGILQNFPMASFRPTDIDLDGGKPTVDGVHYIAEAERLAYADRDKYVADTDFVALP
GNSPDTLLNPTYLAGRARLISGDTTMGVAKPGEFNIPASAAVSTPEHGTSQVTVVDARGNAASLTTTVESAFGSFHMVDG
FFLNNQLTDFSAEPVGKDGLPVANRLQPGKRPRSSMAPTLVFERAESGKRGALLLALGSPGGSVIIQFVVKTLVGILDWG
LDPQQAVSMVDFGANNSPKTNVGGEHPSIDARDNGADDPLIQRLRARGHIVDVADQSSGLSALVRRGPGWIGGADPRREG
LVMGDTG
>Mature_647_residues
MRALTRALAIASIALLASAGCAGDMTSRPGGAAEPCGITANGVPITKTAATQAATERNISTNPEVATGYRTGMTAVRTAS
YAAATANPLATQAACKVLRDGGSAADALVAAQAVLGLVEPQSSGIGGGGFLVYYDAASGAVQTYDGREVAPAAATENYLR
WVDDADRTAPRPDVRSSGRSIGVPGILRMLYDVHAEHGAAPWRELFTPAVQLADDGFEISPRLAAAITDSAASLALDPEA
DLYLLNTDGSAKPAGTKITNPAYAKTLGAVAADGPDAFYRGAIAEAIVAAAADTSSGRTPSLMTTADLSGYTAKRRAALC
TTYRDHEICGMPAPSSGGIAVAATLGILQNFPMASFRPTDIDLDGGKPTVDGVHYIAEAERLAYADRDKYVADTDFVALP
GNSPDTLLNPTYLAGRARLISGDTTMGVAKPGEFNIPASAAVSTPEHGTSQVTVVDARGNAASLTTTVESAFGSFHMVDG
FFLNNQLTDFSAEPVGKDGLPVANRLQPGKRPRSSMAPTLVFERAESGKRGALLLALGSPGGSVIIQFVVKTLVGILDWG
LDPQQAVSMVDFGANNSPKTNVGGEHPSIDARDNGADDPLIQRLRARGHIVDVADQSSGLSALVRRGPGWIGGADPRREG
LVMGDTG

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=556, Percent_Identity=30.0359712230216, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI73915090, Length=556, Percent_Identity=30.0359712230216, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI73915096, Length=556, Percent_Identity=30.0359712230216, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI73915094, Length=556, Percent_Identity=30.0359712230216, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI113429324, Length=557, Percent_Identity=29.6229802513465, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI113429326, Length=561, Percent_Identity=29.2335115864528, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI153266885, Length=493, Percent_Identity=26.9776876267748, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI153266901, Length=489, Percent_Identity=26.9938650306748, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI109148539, Length=619, Percent_Identity=26.4943457189015, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI153266907, Length=493, Percent_Identity=25.7606490872211, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI30581157, Length=229, Percent_Identity=30.1310043668122, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI30581155, Length=229, Percent_Identity=30.1310043668122, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1789856, Length=507, Percent_Identity=33.5305719921105, Blast_Score=238, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI193208247, Length=566, Percent_Identity=31.8021201413428, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI193208245, Length=566, Percent_Identity=31.8021201413428, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI212646519, Length=497, Percent_Identity=30.9859154929577, Blast_Score=181, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI72000294, Length=497, Percent_Identity=30.9859154929577, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17542894, Length=584, Percent_Identity=29.7945205479452, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17506189, Length=571, Percent_Identity=26.0945709281961, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI72001497, Length=467, Percent_Identity=22.0556745182013, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72001495, Length=326, Percent_Identity=23.3128834355828, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323330, Length=476, Percent_Identity=27.5210084033613, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI161077880, Length=575, Percent_Identity=28.5217391304348, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI45551474, Length=575, Percent_Identity=28.5217391304348, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI161077878, Length=575, Percent_Identity=28.5217391304348, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642670, Length=575, Percent_Identity=28.5217391304348, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24642666, Length=575, Percent_Identity=28.5217391304348, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI18859893, Length=478, Percent_Identity=30.9623430962343, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI18859741, Length=501, Percent_Identity=28.1437125748503, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI161077496, Length=465, Percent_Identity=24.9462365591398, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 66536; Mature: 66536

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALTRALAIASIALLASAGCAGDMTSRPGGAAEPCGITANGVPITKTAATQAATERNIS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCC
TNPEVATGYRTGMTAVRTASYAAATANPLATQAACKVLRDGGSAADALVAAQAVLGLVEP
CCCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QSSGIGGGGFLVYYDAASGAVQTYDGREVAPAAATENYLRWVDDADRTAPRPDVRSSGRS
CCCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
IGVPGILRMLYDVHAEHGAAPWRELFTPAVQLADDGFEISPRLAAAITDSAASLALDPEA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCEEEECCCC
DLYLLNTDGSAKPAGTKITNPAYAKTLGAVAADGPDAFYRGAIAEAIVAAAADTSSGRTP
CEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SLMTTADLSGYTAKRRAALCTTYRDHEICGMPAPSSGGIAVAATLGILQNFPMASFRPTD
CEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCC
IDLDGGKPTVDGVHYIAEAERLAYADRDKYVADTDFVALPGNSPDTLLNPTYLAGRARLI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCCEECCCEEEE
SGDTTMGVAKPGEFNIPASAAVSTPEHGTSQVTVVDARGNAASLTTTVESAFGSFHMVDG
ECCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCCEEEECE
FFLNNQLTDFSAEPVGKDGLPVANRLQPGKRPRSSMAPTLVFERAESGKRGALLLALGSP
EEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCEEEEECCCCCCCCEEEEEECCC
GGSVIIQFVVKTLVGILDWGLDPQQAVSMVDFGANNSPKTNVGGEHPSIDARDNGADDPL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IQRLRARGHIVDVADQSSGLSALVRRGPGWIGGADPRREGLVMGDTG
HHHHHHCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCC
>Mature Secondary Structure
MRALTRALAIASIALLASAGCAGDMTSRPGGAAEPCGITANGVPITKTAATQAATERNIS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCC
TNPEVATGYRTGMTAVRTASYAAATANPLATQAACKVLRDGGSAADALVAAQAVLGLVEP
CCCCCCCCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QSSGIGGGGFLVYYDAASGAVQTYDGREVAPAAATENYLRWVDDADRTAPRPDVRSSGRS
CCCCCCCCEEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHCCCC
IGVPGILRMLYDVHAEHGAAPWRELFTPAVQLADDGFEISPRLAAAITDSAASLALDPEA
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCEEEECCCC
DLYLLNTDGSAKPAGTKITNPAYAKTLGAVAADGPDAFYRGAIAEAIVAAAADTSSGRTP
CEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
SLMTTADLSGYTAKRRAALCTTYRDHEICGMPAPSSGGIAVAATLGILQNFPMASFRPTD
CEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCCCCCCCCCC
IDLDGGKPTVDGVHYIAEAERLAYADRDKYVADTDFVALPGNSPDTLLNPTYLAGRARLI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCCCCCCCEECCCEEEE
SGDTTMGVAKPGEFNIPASAAVSTPEHGTSQVTVVDARGNAASLTTTVESAFGSFHMVDG
ECCCEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHHHHHHCCCEEEECE
FFLNNQLTDFSAEPVGKDGLPVANRLQPGKRPRSSMAPTLVFERAESGKRGALLLALGSP
EEECCCCCCCCCCCCCCCCCCHHHHCCCCCCCCHHCCCEEEEECCCCCCCCEEEEEECCC
GGSVIIQFVVKTLVGILDWGLDPQQAVSMVDFGANNSPKTNVGGEHPSIDARDNGADDPL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
IQRLRARGHIVDVADQSSGLSALVRRGPGWIGGADPRREGLVMGDTG
HHHHHHCCCEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA