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The map label for this gene is yybE [H]

Identifier: 169629791

GI number: 169629791

Start: 2753830

End: 2754702

Strand: Direct

Name: yybE [H]

Synonym: MAB_2707

Alternate gene names: 169629791

Gene position: 2753830-2754702 (Clockwise)

Preceding gene: 169629788

Following gene: 169629792

Centisome position: 54.35

GC content: 65.41

Gene sequence:

>873_bases
ATGGCCGAGGGTGACTACGAGTGGTACATCACACTCGCCGAGCTACAGAACGTCACCGCGGCCGCCGACCAGCTCCGGCT
TGCGCAGCCGACACTCACCCGCATGCTGGCCCGTTTGGAACGCCGCCTGGGCGTGCAGCTCTTCGACCGGCACGGTAAGC
GGCTCGCCCTGAATCCATTTGGCCGGATCTTCTACCAACACGCCCGCCGCGCTCAGCTGGAACTGGATTCCGCGCGCCGC
GCAATCGACGATCTCGCGAACCCTGCTGAGGGCGAGATCCGTCTGGGGTTCCTGCACACCTTCGGGCCTACCTTGATCGC
CGGATTGATCGCCGGCTTCGCGACGACATCGCCGCATGTGCGATTCGTCCTGGAACAGGGCGCCGCAGGCAGTCTCGATG
ATCTGGTGGCCACCGGCGACCTGGACGTCGCCATCGTCTCTCCGCGCCCTCGGCGTGCGAATCTCGGCTGGCGCAACCTT
TTCCGGCAACGTCTCGGCGTCGCGGTGCCCACCGACCATCGCCTTGCGCAAGCCCAGGATGTGTCGATGGTTGACCTTGC
CGACGAACCTTTCGTGGCGATGCATCCAGGTTTCGGTATGCGTCGGCTGCTCGAAGAGCTCTGCGCCGCAGCACAATTCC
AACCACGGATCGTGCTGGAATCAAGCAATCTGATGACGGTGGCGGGTCTGGTGGCCGCCGGTCTCGGCGTTACCGTGCTT
CCCGTCGACGCCACCACCTATCCGCCCGACCTGCGGATGTTGCGCCTCATCGACGCCGATGCGCACCGCGACGTCGGGAT
CGTCTGGAGCTCCGGGCAACCGCTGTCGCGGCCCGTCCGCAACTTCATATCCCACGCCGTCGCATCGACGTAG

Upstream 100 bases:

>100_bases
CGTCGCCATGAGTCCCAATGTTGCTCGCGATCAGGCATATTGCGGAAATGAGCAATATTCGGATCTATAATTCATTTTAC
GTATAAACGGAGGTAGAGCC

Downstream 100 bases:

>100_bases
GTAACAATCATTGCCATGTCTGCCGAGGTGCCGGCCGAAAACGGGATGGCCCGGGCCATCGCGCAGATCGATGCTGCCGC
CGACGAAGCGGCGTTCCATG

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPFGRIFYQHARRAQLELDSARR
AIDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHVRFVLEQGAAGSLDDLVATGDLDVAIVSPRPRRANLGWRNL
FRQRLGVAVPTDHRLAQAQDVSMVDLADEPFVAMHPGFGMRRLLEELCAAAQFQPRIVLESSNLMTVAGLVAAGLGVTVL
PVDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVRNFISHAVAST

Sequences:

>Translated_290_residues
MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPFGRIFYQHARRAQLELDSARR
AIDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHVRFVLEQGAAGSLDDLVATGDLDVAIVSPRPRRANLGWRNL
FRQRLGVAVPTDHRLAQAQDVSMVDLADEPFVAMHPGFGMRRLLEELCAAAQFQPRIVLESSNLMTVAGLVAAGLGVTVL
PVDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVRNFISHAVAST
>Mature_289_residues
AEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPFGRIFYQHARRAQLELDSARRA
IDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHVRFVLEQGAAGSLDDLVATGDLDVAIVSPRPRRANLGWRNLF
RQRLGVAVPTDHRLAQAQDVSMVDLADEPFVAMHPGFGMRRLLEELCAAAQFQPRIVLESSNLMTVAGLVAAGLGVTVLP
VDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVRNFISHAVAST

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=249, Percent_Identity=29.718875502008, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=27.1739130434783, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787879, Length=283, Percent_Identity=26.5017667844523, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787530, Length=248, Percent_Identity=27.8225806451613, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI145693105, Length=263, Percent_Identity=26.615969581749, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788296, Length=258, Percent_Identity=27.1317829457364, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367136, Length=235, Percent_Identity=26.3829787234043, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=240, Percent_Identity=25.4166666666667, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789204, Length=270, Percent_Identity=24.0740740740741, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788297, Length=239, Percent_Identity=22.5941422594142, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787806, Length=280, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789639, Length=158, Percent_Identity=31.0126582278481, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=242, Percent_Identity=23.5537190082645, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=241, Percent_Identity=26.5560165975104, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788748, Length=240, Percent_Identity=25, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31826; Mature: 31695

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPF
CCCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCEEEECHH
GRIFYQHARRAQLELDSARRAIDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCE
RFVLEQGAAGSLDDLVATGDLDVAIVSPRPRRANLGWRNLFRQRLGVAVPTDHRLAQAQD
EEEEECCCCCCHHHHEECCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCC
VSMVDLADEPFVAMHPGFGMRRLLEELCAAAQFQPRIVLESSNLMTVAGLVAAGLGVTVL
CEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEE
PVDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVRNFISHAVAST
EECCCCCCCCHHEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEGDYEWYITLAELQNVTAAADQLRLAQPTLTRMLARLERRLGVQLFDRHGKRLALNPF
CCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCEEEECHH
GRIFYQHARRAQLELDSARRAIDDLANPAEGEIRLGFLHTFGPTLIAGLIAGFATTSPHV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCE
RFVLEQGAAGSLDDLVATGDLDVAIVSPRPRRANLGWRNLFRQRLGVAVPTDHRLAQAQD
EEEEECCCCCCHHHHEECCCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCC
VSMVDLADEPFVAMHPGFGMRRLLEELCAAAQFQPRIVLESSNLMTVAGLVAAGLGVTVL
CEEEEECCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCEEEE
PVDATTYPPDLRMLRLIDADAHRDVGIVWSSGQPLSRPVRNFISHAVAST
EECCCCCCCCHHEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]