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The map label for this gene is aofH [H]

Identifier: 169629744

GI number: 169629744

Start: 2703221

End: 2704609

Strand: Direct

Name: aofH [H]

Synonym: MAB_2659

Alternate gene names: 169629744

Gene position: 2703221-2704609 (Clockwise)

Preceding gene: 169629743

Following gene: 169629745

Centisome position: 53.35

GC content: 62.78

Gene sequence:

>1389_bases
ATGTCCAGATCAGTTGATAATGCTGTCGAGGCCGCTTCGGTCGATGTTGTGATTGTCGGCGCAGGCTTTGCCGGTTTGAG
CGCCGCAGATCGGCTCGTGAATATGGGCGTTTCGGTCCTGGTCATCGACGCACGAGAAAGAGTCGGTGGCCGATCGTTCA
CTGGCGAAGTAGCCGGCGTCAAGGTCGACCTCGGGGCAACGTGGGTTGCCAAGCGCCACACCGCGATCCGTGACCTCATG
GACCGCCTGGGCTGTTCGCTGACCCCGCAGTACGACGAAGGCGTCAACCTGCTGTGGATGGCCGGGAAACGTAAGACCTG
GACAGGCACCCTCCCGACGGTCGACCCCGTGGACTTGGAGGACCTAGGGCGAATCACCATCGAGATGGGTAAGTTGCTGG
AGACTATCAATGTCGATGCCGCGTGGAAGTCTCCGAACGCCGACCAGCTCGACTCGATCTCGTTCGGCGAATGGCTCAGC
CAGCAGCAGGCTGTCACCAGCACTAATGCGCTGATGTACATCGTCACCAGGGTGCAGTGGGGCTGCAGCCCGCTCGACGT
GTCGCTGCTGCACGTGTTGCGCTACGTCCAAGCAGTAGGCGGGCTCGACCACATGCTCGCCGTCGAACACGGACAGCAGG
AGTACCGCGTCACCGAAACCACGCAAGAGATCGCCAAGCGCCTCGCTGCACAGATCGGCGACCAGATTGTGCTGAACACC
CGGGTTCGCCAGATCTCCCAAGACGATAACGGCGTCACGGTCTCCACCGACTCGGGAGTGATCAATGCCAAGTACGCCAT
CGTCACGGCGGCCCCAGAGCATCGGGCTTACATCGAGTACCAGCCGGCCCTGCCGGCCAAGATCGAGGGGCTCACAACGA
GCTTCCCGATGGGTGCGCTGAGCAAGGCGTTCGTTGCCTACGACAAGCCCTTCTGGCGGGCTGAGGGACTTTCGGGTGAG
GCGTTGACCGATACCGCGCCGGTGTTCATCACCTTCGACGTGTCACCCAGCGATGACGGGCCGGGAATCCTCATGGTCTT
CTGCACCGCTCGGGTGTACGACGGCTTCGGCCCGGAGGTTCGCCGGAAACTGGTTCTCAAACAATTGGTCGACCTGTACG
GCGAGCAGGCCAACACCCCGATCGACTACATCGATCACTGCTGGGGCACCGAACCATTCGCCGCGGGCGGCCCGCACCCG
GCCGCGCCGCCTTTTGCATCGGTGAACTACGGCGAGGCCCTCAGAGAGCCGCACGGGCGCATTCACTGGGCAGGTACCGA
AACCGCGGGCGAGTGGGTCGGAACCATGAACGGCGCCATCCTGATGGGCCTGCACACCGCCGATCAGATCGCCCAGCAGC
TCGGCGTCACAGGAGAGGTCTCGAAGTAA

Upstream 100 bases:

>100_bases
ACAGAACTGTGGCCGACTCAACCCCCGAAGACGTCCCGCGGTCTGCCAACCACGCAAGCGCGGGAGAAAACCATGAAAGA
AACCCAACGAAGGAGGAGCA

Downstream 100 bases:

>100_bases
ACCTCGTCCCGGTGCCCTCGGGGGTCTGTCTACCCCGAGGGCACCGCCGTGGTTCTGCCTATTGATCTCCGCAACGGATC
GGACATGCATTCGATACGTC

Product: putative flavin-containing monoamine oxidase AofH

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGVKVDLGATWVAKRHTAIRDLM
DRLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLEDLGRITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLS
QQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNT
RVRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTTSFPMGALSKAFVAYDKPFWRAEGLSGE
ALTDTAPVFITFDVSPSDDGPGILMVFCTARVYDGFGPEVRRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHP
AAPPFASVNYGEALREPHGRIHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK

Sequences:

>Translated_462_residues
MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGVKVDLGATWVAKRHTAIRDLM
DRLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLEDLGRITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLS
QQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNT
RVRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTTSFPMGALSKAFVAYDKPFWRAEGLSGE
ALTDTAPVFITFDVSPSDDGPGILMVFCTARVYDGFGPEVRRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHP
AAPPFASVNYGEALREPHGRIHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
>Mature_461_residues
SRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGVKVDLGATWVAKRHTAIRDLMD
RLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLEDLGRITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLSQ
QQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNTR
VRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTTSFPMGALSKAFVAYDKPFWRAEGLSGEA
LTDTAPVFITFDVSPSDDGPGILMVFCTARVYDGFGPEVRRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHPA
APPFASVNYGEALREPHGRIHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=471, Percent_Identity=30.7855626326964, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI38202207, Length=448, Percent_Identity=30.1339285714286, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI193202177, Length=456, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 49866; Mature: 49735

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGV
CCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHCCCCCCCCCEEEE
KVDLGATWVAKRHTAIRDLMDRLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLE
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCCCCHH
DLGRITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLSQQQAVTSTNALMYIVTRVQW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHC
GCSPLDVSLLHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNT
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEH
RVRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTTSFPMGAL
HHHHHCCCCCCEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCCHHHH
SKAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGILMVFCTARVYDGFGPEV
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHHHHCCCCHHH
RRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHPAAPPFASVNYGEALREPHGR
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCE
IHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
EEEECCCCCHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMGVSVLVIDARERVGGRSFTGEVAGV
CCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECHHHCCCCCCCCCEEEE
KVDLGATWVAKRHTAIRDLMDRLGCSLTPQYDEGVNLLWMAGKRKTWTGTLPTVDPVDLE
EEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCCCCHH
DLGRITIEMGKLLETINVDAAWKSPNADQLDSISFGEWLSQQQAVTSTNALMYIVTRVQW
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHC
GCSPLDVSLLHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNT
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHEEHHHHHHHHHHHHHHCCCEEEEEH
RVRQISQDDNGVTVSTDSGVINAKYAIVTAAPEHRAYIEYQPALPAKIEGLTTSFPMGAL
HHHHHCCCCCCEEEECCCCEEEEEEEEEEECCCCCEEEEECCCCCCEECCCCCCCCHHHH
SKAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGILMVFCTARVYDGFGPEV
HHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEHHHHCCCCHHH
RRKLVLKQLVDLYGEQANTPIDYIDHCWGTEPFAAGGPHPAAPPFASVNYGEALREPHGR
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCE
IHWAGTETAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
EEEECCCCCHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]