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The map label for this gene is ctaD [H]

Identifier: 169629703

GI number: 169629703

Start: 2658327

End: 2660021

Strand: Reverse

Name: ctaD [H]

Synonym: MAB_2617c

Alternate gene names: 169629703

Gene position: 2660021-2658327 (Counterclockwise)

Preceding gene: 169629707

Following gene: 169629702

Centisome position: 52.5

GC content: 61.71

Gene sequence:

>1695_bases
ATGAGCGCACAAACGCAGTTTCTCGTGCCGGTGCCGGCCCAGCGCCCCTTTCCGGCGCGGGGTCTGCGCGGCACTCTCGT
CTACCGGCTGCTCGGCACCACCGATCACAAGTTGATCGGCGTGATGTACGTCGTCACCTGCTTCGGCTTTTTCTTCGTGG
GCGGGTTGATGGCCCTGCTGATGCGTGCTGAACTGGTTCATCCCGGGCTTCAATTCCTCTCGAATGAGCAGTACAACCAA
CTGTTCACCATGCACGGCACGGTCATGCTGCTGTTCTACGCCACGCCGATCGTGTTCGGCTTCGCCAATCTGGTGCTGCC
GCTGCATATCGGCGCGCCAGATGTGGCTTTTCCGCGCTTGAATGCCTTGTCCTACTGGCTGTTTCTGTGCGGCGGATTGA
TCACCCTGGCCGGGTTCATCGCGCCGGGCGGCGCCGCCGACTTTGGCTGGACCGCCTATGCGCCGCTTTCCAATGCCGTA
CACAGTCCCGGGGTGGGCGGAGACCTGTGGATCATGGGTCTGGCCGTCGGCGGGGTCGGCACCATCCTTGGGGCCGTGAA
CATGATCACCACGGTCGTGTGTATGCGTGCCCCGGGTATGACGATGTTCCGGATGCCGATCTTCACCTGGAACATCCTGG
TGACCAGCTGGCTCGTGCTGATCGCGTTCCCGCTGCTGACCGCCGCGCTGTTCGGTCTGGCTGCCGACCGCCACCTCGGA
GCCCATATCTTCGACCCTGCCAACGGGGGGCCGATCCTCTGGCAGCACTTGTTCTGGTTCTTCGGACATCCCGAGGTCTA
TATCGTCGCCTTGCCGTTCTTTGGCATCGTGTCGGAGATCTTCCCGGTGTTCAGCCGCAAGCCCATATTCGGTTACCACA
CATTGGTTTACGCGACCGTTGGCATCGGGATTCTATCCGTGGCCGTGTGGGCGCACCACATGTTCGCCACCGGCGCGGTG
CTCCTGCCGTTCTTCTCCTTCATGACCTATCTCATCGCAGTGCCGACGGGCATCAAGTTCTTCAACTGGATCGGCACCAT
GTGGAAGGGGCAGTTGACCTTCGAGACCCCCATGCTGTTCGCGGTCGGGTTCTTGGTCACGTTCCTCTTCGGAGGGTTGA
CCGGTGTCTTGCTCGCCTCACCGCCCCTGGATTTCCATGTGACCGACTCGTATTTTGTGGTCGCACATTTTCACTACGTG
CTCTTCGGCACCATCGTCTTCTCAACCTTCGCCGGGGTGTACTTCTGGTTCCCAAAGATGACGGGCCGTCTGCTCGACGA
GCGCCTGGGCAAGTTCCACTTCTGGCTGACCTTCATCGGCTTCCACTCGACGTTCCTGGTGCAGCACTGGCTGGGTAACG
AGGGCATGCCCCGCCGGTACGCCGACTACCTGCCCTCTGACGGCTTCACGGATTTGAACATCGTGTCCACGGTTGGCGCC
TTCATTCTCGGGGCTTCCATGCTGCCGTTCCTGTGGAACGTGTTCACGAGCTACCGCTACGGCGAGGTTGTCACGGTCGA
TGATCCGTGGGGCTACGGCAACTCTCTGGAGTGGGCCACCAGCTGCCCGCCGCCGCGGCACAACTTCTCCGAGCTGCCCC
AAATCCGGTCCGAGCGCCCGGCCTTCGAACTGCACTATCCGCACATGTCTGAGCGCATGCGCGCCGAGGCACACGTGGTG
CGTGCGCAGCCTTGA

Upstream 100 bases:

>100_bases
GTGTAGATACGCAACGCATCTGTTGGGTCGTAACCATGTTGAGTACACGAAATCTGTCACGAGTCCACGGGCAGGCCGCC
ACGGCCCGCCGGGAACTCGG

Downstream 100 bases:

>100_bases
CACCATGTGCTTCTACGAGTTAGCGAGGATCTATGGGTATCGCGTTCAATCACACAATCGTTCATTCCGAGAACCGTGAA
GAATCGGCCCGGTTCTTCAC

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MSAQTQFLVPVPAQRPFPARGLRGTLVYRLLGTTDHKLIGVMYVVTCFGFFFVGGLMALLMRAELVHPGLQFLSNEQYNQ
LFTMHGTVMLLFYATPIVFGFANLVLPLHIGAPDVAFPRLNALSYWLFLCGGLITLAGFIAPGGAADFGWTAYAPLSNAV
HSPGVGGDLWIMGLAVGGVGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSWLVLIAFPLLTAALFGLAADRHLG
AHIFDPANGGPILWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYHTLVYATVGIGILSVAVWAHHMFATGAV
LLPFFSFMTYLIAVPTGIKFFNWIGTMWKGQLTFETPMLFAVGFLVTFLFGGLTGVLLASPPLDFHVTDSYFVVAHFHYV
LFGTIVFSTFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNEGMPRRYADYLPSDGFTDLNIVSTVGA
FILGASMLPFLWNVFTSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPQIRSERPAFELHYPHMSERMRAEAHVV
RAQP

Sequences:

>Translated_564_residues
MSAQTQFLVPVPAQRPFPARGLRGTLVYRLLGTTDHKLIGVMYVVTCFGFFFVGGLMALLMRAELVHPGLQFLSNEQYNQ
LFTMHGTVMLLFYATPIVFGFANLVLPLHIGAPDVAFPRLNALSYWLFLCGGLITLAGFIAPGGAADFGWTAYAPLSNAV
HSPGVGGDLWIMGLAVGGVGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSWLVLIAFPLLTAALFGLAADRHLG
AHIFDPANGGPILWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYHTLVYATVGIGILSVAVWAHHMFATGAV
LLPFFSFMTYLIAVPTGIKFFNWIGTMWKGQLTFETPMLFAVGFLVTFLFGGLTGVLLASPPLDFHVTDSYFVVAHFHYV
LFGTIVFSTFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNEGMPRRYADYLPSDGFTDLNIVSTVGA
FILGASMLPFLWNVFTSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPQIRSERPAFELHYPHMSERMRAEAHVV
RAQP
>Mature_563_residues
SAQTQFLVPVPAQRPFPARGLRGTLVYRLLGTTDHKLIGVMYVVTCFGFFFVGGLMALLMRAELVHPGLQFLSNEQYNQL
FTMHGTVMLLFYATPIVFGFANLVLPLHIGAPDVAFPRLNALSYWLFLCGGLITLAGFIAPGGAADFGWTAYAPLSNAVH
SPGVGGDLWIMGLAVGGVGTILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSWLVLIAFPLLTAALFGLAADRHLGA
HIFDPANGGPILWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYHTLVYATVGIGILSVAVWAHHMFATGAVL
LPFFSFMTYLIAVPTGIKFFNWIGTMWKGQLTFETPMLFAVGFLVTFLFGGLTGVLLASPPLDFHVTDSYFVVAHFHYVL
FGTIVFSTFAGVYFWFPKMTGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNEGMPRRYADYLPSDGFTDLNIVSTVGAF
ILGASMLPFLWNVFTSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPQIRSERPAFELHYPHMSERMRAEAHVVR
AQP

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=44.8742746615087, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1786634, Length=533, Percent_Identity=44.6529080675422, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6226519, Length=538, Percent_Identity=39.2193308550186, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=40.9230769230769, Blast_Score=236, Evalue=9e-63,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=36.6533864541833, Blast_Score=146, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 62788; Mature: 62657

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQTQFLVPVPAQRPFPARGLRGTLVYRLLGTTDHKLIGVMYVVTCFGFFFVGGLMALL
CCCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MRAELVHPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVLPLHIGAPDVAFPRL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHH
NALSYWLFLCGGLITLAGFIAPGGAADFGWTAYAPLSNAVHSPGVGGDLWIMGLAVGGVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHCCCCCCCCCHHHHHHHHHHHHH
TILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSWLVLIAFPLLTAALFGLAADRHLG
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AHIFDPANGGPILWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYHTLVYATV
CEEECCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GIGILSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWKGQLTFETPMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHHH
AVGFLVTFLFGGLTGVLLASPPLDFHVTDSYFVVAHFHYVLFGTIVFSTFAGVYFWFPKM
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNEGMPRRYADYLPSDGFTDLNIVSTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHH
FILGASMLPFLWNVFTSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPQIRSERP
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
AFELHYPHMSERMRAEAHVVRAQP
CEEEECCCHHHHHHHHHHEEECCC
>Mature Secondary Structure 
SAQTQFLVPVPAQRPFPARGLRGTLVYRLLGTTDHKLIGVMYVVTCFGFFFVGGLMALL
CCCCCEEEECCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MRAELVHPGLQFLSNEQYNQLFTMHGTVMLLFYATPIVFGFANLVLPLHIGAPDVAFPRL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHH
NALSYWLFLCGGLITLAGFIAPGGAADFGWTAYAPLSNAVHSPGVGGDLWIMGLAVGGVG
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHCCCCCCCCCHHHHHHHHHHHHH
TILGAVNMITTVVCMRAPGMTMFRMPIFTWNILVTSWLVLIAFPLLTAALFGLAADRHLG
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AHIFDPANGGPILWQHLFWFFGHPEVYIVALPFFGIVSEIFPVFSRKPIFGYHTLVYATV
CEEECCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GIGILSVAVWAHHMFATGAVLLPFFSFMTYLIAVPTGIKFFNWIGTMWKGQLTFETPMLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCHHHH
AVGFLVTFLFGGLTGVLLASPPLDFHVTDSYFVVAHFHYVLFGTIVFSTFAGVYFWFPKM
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRLLDERLGKFHFWLTFIGFHSTFLVQHWLGNEGMPRRYADYLPSDGFTDLNIVSTVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCHHHHHHHHH
FILGASMLPFLWNVFTSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFSELPQIRSERP
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
AFELHYPHMSERMRAEAHVVRAQP
CEEEECCCHHHHHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]