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The map label for this gene is modB [H]

Identifier: 169629520

GI number: 169629520

Start: 2490500

End: 2491300

Strand: Direct

Name: modB [H]

Synonym: MAB_2434

Alternate gene names: 169629520

Gene position: 2490500-2491300 (Clockwise)

Preceding gene: 169629519

Following gene: 169629521

Centisome position: 49.15

GC content: 68.41

Gene sequence:

>801_bases
GTGACCCCGGCCCCCGGTCTGCCGCGCTGGGTCTATGTGCCCGCGGCCATCGGGGCAGCGCTCATCGTGCTGCCGCTGCT
GGCGCTGGTGGTGAAGGCCGATTGGGGGCAGTTCCCGGCGCTGGTCACCAGCCCGGCATCGCAGGCGGCGCTGTTGCTCA
GCGTCAGGACCTGTCTGGCTAGCACGGCGCTGTGTCTGTTGTTCGGAGTGCCGCTGGCGGTGGTGTTGGCTCGTGGGCCC
GGGCGGATGACTCGGCTGCTGCGCCCGATGATCCTGTTGCCACTGGTGTTGCCGCCGGTGGTCGGCGGCATCGCGCTGCT
CTATGCCTTCGGAAAGCTGGGGTTGCTGGGCCACTACCTGGACGCCGCGGGGATTCGCATCGCGTACTCCACGTCTGCCG
TGGTTCTGGCGCAGACCTTTGTCTCGCTGCCGTTCCTGGTCATCAGTTTGCAGGGTGCGCTGACCACGACCGGACAGCGC
TATGACGAGGTGGCCGCGAGTCTGGGTGCCCCACCCACCACCGTGTTGCGCCGCGTCTCGTTGCCCCTGGTGATGCCGGC
GCTCGCCTCGGGCACTGTGCTGGCTTTCGCGCGTTCGCTAGGGGAGTTCGGTGCCACATTGACCTTCGCGGGATCGCGGC
AGGGTGTGACGCGCACCCTGCCCCTGGAGATCTATCTGCAACGGGAATCCGATCCGCAGGCCGCGGTGGCGCTGTCGCTG
CTATTGGTGGCGGTGGCGGCGGTTGTCCTTGCCGTTGTCGGTGCACGGACCCGACGCCCGGCGGGTGGCGGTTATGAGTG
A

Upstream 100 bases:

>100_bases
CGGCGAATTCACGTCATCCAGAGCGCGCCGCCCAGTTTATCGAAACCGTGACCGGCGATATCGGTCACAAGGTGTTGGCG
GCGGCGGGGTTCTCCGCGCC

Downstream 100 bases:

>100_bases
GCTGCGATTCGACGCGGGTCACCTCGCCCGTGGGGTACGGGCGAGGTTCACCGTCGCCGCGGGTGAGACATTGGCGATCG
TCGGCGCCAATGGGGCGGGC

Product: molybdenum ABC transporter permease

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTPAPGLPRWVYVPAAIGAALIVLPLLALVVKADWGQFPALVTSPASQAALLLSVRTCLASTALCLLFGVPLAVVLARGP
GRMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGLLGHYLDAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQR
YDEVAASLGAPPTTVLRRVSLPLVMPALASGTVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRESDPQAAVALSL
LLVAVAAVVLAVVGARTRRPAGGGYE

Sequences:

>Translated_266_residues
MTPAPGLPRWVYVPAAIGAALIVLPLLALVVKADWGQFPALVTSPASQAALLLSVRTCLASTALCLLFGVPLAVVLARGP
GRMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGLLGHYLDAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQR
YDEVAASLGAPPTTVLRRVSLPLVMPALASGTVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRESDPQAAVALSL
LLVAVAAVVLAVVGARTRRPAGGGYE
>Mature_265_residues
TPAPGLPRWVYVPAAIGAALIVLPLLALVVKADWGQFPALVTSPASQAALLLSVRTCLASTALCLLFGVPLAVVLARGPG
RMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGLLGHYLDAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQRY
DEVAASLGAPPTTVLRRVSLPLVMPALASGTVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRESDPQAAVALSLL
LVAVAAVVLAVVGARTRRPAGGGYE

Specific function: Part of the binding-protein-dependent transport system modABCD for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=219, Percent_Identity=35.6164383561644, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788764, Length=211, Percent_Identity=33.6492890995261, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786980, Length=230, Percent_Identity=38.695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787369, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787080, Length=224, Percent_Identity=27.2321428571429, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787368, Length=223, Percent_Identity=28.6995515695067, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867
- InterPro:   IPR006469 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27494; Mature: 27363

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAPGLPRWVYVPAAIGAALIVLPLLALVVKADWGQFPALVTSPASQAALLLSVRTCLA
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHH
STALCLLFGVPLAVVLARGPGRMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGLLGHYL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQRYDEVAASLGAPPTTVLRRVS
HHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHCCCHHHHHHHHC
LPLVMPALASGTVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRESDPQAAVALSL
CHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCEEEECEEEEEECCCCHHHHHHHHH
LLVAVAAVVLAVVGARTRRPAGGGYE
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TPAPGLPRWVYVPAAIGAALIVLPLLALVVKADWGQFPALVTSPASQAALLLSVRTCLA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHH
STALCLLFGVPLAVVLARGPGRMTRLLRPMILLPLVLPPVVGGIALLYAFGKLGLLGHYL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAAGIRIAYSTSAVVLAQTFVSLPFLVISLQGALTTTGQRYDEVAASLGAPPTTVLRRVS
HHCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHCCCHHHHHHHHC
LPLVMPALASGTVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRESDPQAAVALSL
CHHHHHHHHCCHHHHHHHHHHHHCCEEEECCCCCCCEEEECEEEEEECCCCHHHHHHHHH
LLVAVAAVVLAVVGARTRRPAGGGYE
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]