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The map label for this gene is infC [H]

Identifier: 169629407

GI number: 169629407

Start: 2377114

End: 2377644

Strand: Direct

Name: infC [H]

Synonym: MAB_2321

Alternate gene names: 169629407

Gene position: 2377114-2377644 (Clockwise)

Preceding gene: 169629402

Following gene: 169629408

Centisome position: 46.91

GC content: 65.16

Gene sequence:

>531_bases
GTGCGGATCGAAGATGCGCTCCGCGTCGCAGCCGACGCCGATCTCGACCTTGTCGAGGTAGCCCCAGATGCCAGACCGCC
GGTCTGCAAGATCATGGACTACGGCAAGTTCAAGTACGAGACGGCCCAGAAAGCGCGTGAGTCTCGCAAGAATCAGCAAC
AGACCGTCGTCAAGGAACAGAAGCTTCGGCCCAAGATCGACGATCACGACTACGAAACCAAGAAGGGCCACGTGGTCCGC
TTCTTGGAAGCCGGATCCAAGGTCAAGGTCACGATCATGTTCCGCGGACGTGAGCAGTCCCGGCCCGAACTGGGATACCG
GCTGCTGCAGCGGCTCGGCGCGGACGTCGCCGACTACGGCTTCGTGGAGACATCCGCGAAGCAGGACGGCCGCAACATGA
CGATGGTGCTGGCGCCGCACCGGGGCGCGAAGACCCGGGCCAAGGCGGCACAGCAGGCGGAGGCTCCTGCAGGACCGGCG
ACGGCTTCGGCGGCCGCGCCGGCCGAGCAAGCGCCCACCGAACAGACCTAG

Upstream 100 bases:

>100_bases
GAGCCAGGGAGGCCACATCAGCACTGAGACCCGCATCAATGAACGTATCCGCGTACCCGAAGTCCGCCTGATCGGCCCGA
AAGGCGAGCAGGTCGGCATC

Downstream 100 bases:

>100_bases
TACGGAAAACAAAGGAACAGGGAACACCAAGATGCCCAAGGCCAAGACCCACAGCGGTGCGTCGAAGCGCTTCCGCACCA
CCGGTAGCGGAAAGATCGTG

Product: translation initiation factor IF-3 (InfC)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRIEDALRVAADADLDLVEVAPDARPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKGHVVR
FLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAQQAEAPAGPA
TASAAAPAEQAPTEQT

Sequences:

>Translated_176_residues
MRIEDALRVAADADLDLVEVAPDARPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKGHVVR
FLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAQQAEAPAGPA
TASAAAPAEQAPTEQT
>Mature_176_residues
MRIEDALRVAADADLDLVEVAPDARPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQKLRPKIDDHDYETKKGHVVR
FLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFVETSAKQDGRNMTMVLAPHRGAKTRAKAAQQAEAPAGPA
TASAAAPAEQAPTEQT

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=140, Percent_Identity=45.7142857142857, Blast_Score=120, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19464; Mature: 19464

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEDALRVAADADLDLVEVAPDARPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQ
CCHHHHHHHHCCCCCEEEEECCCCCCCEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYG
HCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
FVETSAKQDGRNMTMVLAPHRGAKTRAKAAQQAEAPAGPATASAAAPAEQAPTEQT
CEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure
MRIEDALRVAADADLDLVEVAPDARPPVCKIMDYGKFKYETAQKARESRKNQQQTVVKEQ
CCHHHHHHHHCCCCCEEEEECCCCCCCEEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYG
HCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
FVETSAKQDGRNMTMVLAPHRGAKTRAKAAQQAEAPAGPATASAAAPAEQAPTEQT
CEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]