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The map label for this gene is fabF [H]

Identifier: 169629115

GI number: 169629115

Start: 2026904

End: 2028217

Strand: Direct

Name: fabF [H]

Synonym: MAB_2028

Alternate gene names: 169629115

Gene position: 2026904-2028217 (Clockwise)

Preceding gene: 169629114

Following gene: 169629116

Centisome position: 40.0

GC content: 62.86

Gene sequence:

>1314_bases
ATGGAGCTACAGAAACAGTCACCTGACGACGACGATGTAGTCATCACAGGGATTGGACTTGTCGCGGGGACGGTTACTGA
TCCCGAGGAGCTATTTTGGCAGTTGGCTGACGGTGCCTCCTTCATCCGGCAACACCAAGAGCATCGCGATGCTGAGTTGC
CCGCGTCGGTTTCTGGGCATGTCGATGAGGAGACCGTGCGCAAGCTGGCGCGCGCGCTGCCCGAGCAGGCGGCTCGGGTT
GGTGCGGCCGGCGTGCTCGGATGGCATGCGGCAGTACAGGCTTGGAAGCGCAGTGGCCTGCCTAACCTTGCGGGCAGCGA
CCGGGTCGGCGTGTTTGCCGCGTGCAACAAGCTGGCCTTCGCGCCAGACACGCTCGCGGATCTGTCTCGGCTCTATGACC
GGCAAGCCGGCACGTTCGATCTCGACGCCTACCTGGACCACCTCGAGGCCGTATCGGATCTTCCGGATGATCTTCTGCAG
TTTCTTCCGGATACGATGACCGCCTCTCTGGCCGAGTATTTCGGCCTTGGTGGGCCGCTGGTGACGCATGCGGAGGCTTG
TGCCGCGGGCGGTGTGGCGATCGGCAGCGGTTACCGGCATATTCGCTCAGGCGAATTGGATGTGGCGCTGGTCGGCGGCG
CCGAGCGGCTGACCACCTACAGCATCGTCACGGCTTTCGCCGCGCTCGGCGCGCTCGCTCCCACCGGTGACAAACCAAGC
GCCGAGATAAGCAGGCCATTCGACAAGGGGCGCAACGGTTTCGTCATCGCGGACGGCGCCGCGTTCCTTGTGCTGGAGCG
ACGCTCGCATGCCGAAGCACGTGGTGCACAGGCGCTGGCAAGAGTCGCCGGCTACATGGGTACCGCCGAGGCGGTACGGA
TAACCTCAAGCGAGCGAGACGGCGCGACATACGCGGAATGTATGCGGGCCGCGATCGCTGATGCCGGTCTGAGTCCGTCA
GACATACATCATGTGAACGCGCACGGGACGGGCACGCAAGCCAACGACGAGTGCGAAGCTGCAGCCCTGCACTTGGTGTT
CGGTGCCGGTGCGGCCTCAATTCCGTTGACCAGCACCAAGTCTTCGCTCGGCCATGGTTTTGCGGCAAGCGGCGCCATCG
AAGCCGTGCTGTCTGCGATGAGCTTGCGTGAACAGATTATTCCGCCCACGCTGAATTTCAGCGAACCGGACGATGTCACG
AAAGGGCTCGACGTAGTCACCAAGGCCCGGCACCACGAATTTGACACCGTGCTCTCGAACTCCTTCGGCTTTGGCGGCAT
GAACTGCACACTGATCCTGGCAAAGGAAGCGTGA

Upstream 100 bases:

>100_bases
AGATCACCGGCGATGAACTTCTGGTCGCCGATGTGCGAGAAGCGCTTACTCAGGCCAACTCGGTTGTCGCATAGCGCCTT
TAGCTAAAGCATCATCACAG

Downstream 100 bases:

>100_bases
CCCTCAATGAATCAACGCTTGGCGGTAGGACTGTGTAATCCAGGCTTGTATTCGGCAACCGGGCTTGGCGTGGAGACCGT
ATGGGAAGCACTGCGAGTAG

Product: 3-oxoacyl-(Acyl-carrier-protein) synthase II KasB

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MELQKQSPDDDDVVITGIGLVAGTVTDPEELFWQLADGASFIRQHQEHRDAELPASVSGHVDEETVRKLARALPEQAARV
GAAGVLGWHAAVQAWKRSGLPNLAGSDRVGVFAACNKLAFAPDTLADLSRLYDRQAGTFDLDAYLDHLEAVSDLPDDLLQ
FLPDTMTASLAEYFGLGGPLVTHAEACAAGGVAIGSGYRHIRSGELDVALVGGAERLTTYSIVTAFAALGALAPTGDKPS
AEISRPFDKGRNGFVIADGAAFLVLERRSHAEARGAQALARVAGYMGTAEAVRITSSERDGATYAECMRAAIADAGLSPS
DIHHVNAHGTGTQANDECEAAALHLVFGAGAASIPLTSTKSSLGHGFAASGAIEAVLSAMSLREQIIPPTLNFSEPDDVT
KGLDVVTKARHHEFDTVLSNSFGFGGMNCTLILAKEA

Sequences:

>Translated_437_residues
MELQKQSPDDDDVVITGIGLVAGTVTDPEELFWQLADGASFIRQHQEHRDAELPASVSGHVDEETVRKLARALPEQAARV
GAAGVLGWHAAVQAWKRSGLPNLAGSDRVGVFAACNKLAFAPDTLADLSRLYDRQAGTFDLDAYLDHLEAVSDLPDDLLQ
FLPDTMTASLAEYFGLGGPLVTHAEACAAGGVAIGSGYRHIRSGELDVALVGGAERLTTYSIVTAFAALGALAPTGDKPS
AEISRPFDKGRNGFVIADGAAFLVLERRSHAEARGAQALARVAGYMGTAEAVRITSSERDGATYAECMRAAIADAGLSPS
DIHHVNAHGTGTQANDECEAAALHLVFGAGAASIPLTSTKSSLGHGFAASGAIEAVLSAMSLREQIIPPTLNFSEPDDVT
KGLDVVTKARHHEFDTVLSNSFGFGGMNCTLILAKEA
>Mature_437_residues
MELQKQSPDDDDVVITGIGLVAGTVTDPEELFWQLADGASFIRQHQEHRDAELPASVSGHVDEETVRKLARALPEQAARV
GAAGVLGWHAAVQAWKRSGLPNLAGSDRVGVFAACNKLAFAPDTLADLSRLYDRQAGTFDLDAYLDHLEAVSDLPDDLLQ
FLPDTMTASLAEYFGLGGPLVTHAEACAAGGVAIGSGYRHIRSGELDVALVGGAERLTTYSIVTAFAALGALAPTGDKPS
AEISRPFDKGRNGFVIADGAAFLVLERRSHAEARGAQALARVAGYMGTAEAVRITSSERDGATYAECMRAAIADAGLSPS
DIHHVNAHGTGTQANDECEAAALHLVFGAGAASIPLTSTKSSLGHGFAASGAIEAVLSAMSLREQIIPPTLNFSEPDDVT
KGLDVVTKARHHEFDTVLSNSFGFGGMNCTLILAKEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=429, Percent_Identity=30.0699300699301, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI41872631, Length=274, Percent_Identity=28.8321167883212, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI223972627, Length=169, Percent_Identity=35.5029585798817, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI1787337, Length=281, Percent_Identity=42.7046263345196, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1788663, Length=430, Percent_Identity=31.6279069767442, Blast_Score=173, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71983541, Length=285, Percent_Identity=34.0350877192982, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=35.2272727272727, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI212642053, Length=267, Percent_Identity=31.0861423220974, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=291, Percent_Identity=28.1786941580756, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=317, Percent_Identity=30.5993690851735, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24644341, Length=280, Percent_Identity=40, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI221330659, Length=272, Percent_Identity=29.4117647058824, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19920632, Length=272, Percent_Identity=29.4117647058824, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24581345, Length=276, Percent_Identity=30.0724637681159, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 45698; Mature: 45698

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELQKQSPDDDDVVITGIGLVAGTVTDPEELFWQLADGASFIRQHQEHRDAELPASVSGH
CCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VDEETVRKLARALPEQAARVGAAGVLGWHAAVQAWKRSGLPNLAGSDRVGVFAACNKLAF
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
APDTLADLSRLYDRQAGTFDLDAYLDHLEAVSDLPDDLLQFLPDTMTASLAEYFGLGGPL
CCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCH
VTHAEACAAGGVAIGSGYRHIRSGELDVALVGGAERLTTYSIVTAFAALGALAPTGDKPS
HHHHHHHHCCCEEECCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
AEISRPFDKGRNGFVIADGAAFLVLERRSHAEARGAQALARVAGYMGTAEAVRITSSERD
CHHCCHHHCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GATYAECMRAAIADAGLSPSDIHHVNAHGTGTQANDECEAAALHLVFGAGAASIPLTSTK
CCHHHHHHHHHHHHCCCCHHHCEEEECCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCH
SSLGHGFAASGAIEAVLSAMSLREQIIPPTLNFSEPDDVTKGLDVVTKARHHEFDTVLSN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SFGFGGMNCTLILAKEA
CCCCCCCCEEEEEEECC
>Mature Secondary Structure
MELQKQSPDDDDVVITGIGLVAGTVTDPEELFWQLADGASFIRQHQEHRDAELPASVSGH
CCCCCCCCCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
VDEETVRKLARALPEQAARVGAAGVLGWHAAVQAWKRSGLPNLAGSDRVGVFAACNKLAF
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
APDTLADLSRLYDRQAGTFDLDAYLDHLEAVSDLPDDLLQFLPDTMTASLAEYFGLGGPL
CCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCH
VTHAEACAAGGVAIGSGYRHIRSGELDVALVGGAERLTTYSIVTAFAALGALAPTGDKPS
HHHHHHHHCCCEEECCCCHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCC
AEISRPFDKGRNGFVIADGAAFLVLERRSHAEARGAQALARVAGYMGTAEAVRITSSERD
CHHCCHHHCCCCCEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
GATYAECMRAAIADAGLSPSDIHHVNAHGTGTQANDECEAAALHLVFGAGAASIPLTSTK
CCHHHHHHHHHHHHCCCCHHHCEEEECCCCCCCCCCHHHHHHHHHHEECCCCCCCCCCCH
SSLGHGFAASGAIEAVLSAMSLREQIIPPTLNFSEPDDVTKGLDVVTKARHHEFDTVLSN
HHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SFGFGGMNCTLILAKEA
CCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]