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The map label for this gene is mraY

Identifier: 169629090

GI number: 169629090

Start: 2001747

End: 2002826

Strand: Direct

Name: mraY

Synonym: MAB_2003

Alternate gene names: 169629090

Gene position: 2001747-2002826 (Clockwise)

Preceding gene: 169629089

Following gene: 169629091

Centisome position: 39.5

GC content: 63.8

Gene sequence:

>1080_bases
ATGAGGCAGATCATCATTGCCGCCGGTATCGCGATCCTGGTCTCGATCATGCTCACCCCGGTACTCATCCGGGTGTTTTC
ACGGCAGGGATTCGGCCAGGAGATTCGCGACGACGGCCCGCAGCATCATCAGAAGAAGCGGGGCACCCCGTCGATGGGTG
GTGTCGCGATCTTGGCGGGCATGTGGGCCGGTTACTTCGGGTCGCACCTGGTCGGCATCGCGTTCGGGTCCGATGGCCCG
TCGGCATCGGGTCTGCTGGTGCTCGCGCTGGCGACCATGCTCGGGGGCGTCGGCTTCATCGATGACTTCATCAAGATTCG
CAAGGCGCGCAACCTGGGTCTGAACAAGACCTCCAAGACGGTCGGACAGATCCTCTCGGCGCTCGTATTCGGCGTTTTGG
TGCTGCAGTTCCGCAACACCGACGGGCTGACCCCAGGCAGCCCGCAGCTGTCCTACGTGCGTGAGATCGCCACTGTCGCC
ATGCCCGCCGCGATCTTCGTGCTCTTCTGCGTGATCCTGGTCATGTCCTGGTCCAATGCCGTCAACTTCACCGATGGGCT
CGACGGGCTGGCCGGCGGCTGCATGGCGATGGTGACGGGCGCCTACGTGATCGTCACCTTCTGGCAGTACCGCAACGCGT
GCTCCACCCATCCGGGCATCGCCTGCTACAACGTGCGTGACCCACTGGATCTGGCGGTCATCGCCGCGGCGACGGCGGGC
GCATGCATCGGATTCCTGTGGTGGAATGCCGCCCCGGCCAAGATCTTCATGGGAGACACCGGATCGCTGGCCCTCGGTGG
GGTCATCGCGGGCCTGTCGGTGACCACCCGGACCGAGTTACTTGCCGTGGTGCTGGGGGCACTGTTCGTCGCGGAGATCG
TGTCGGTGGTTTTGCAGATCGCGGCATTCCGGACCACGGGCCGCCGGGTCTTTCGGATGGCGCCCTTCCATCATCATTTC
GAGCTACTGGGGTGGGCCGAAACAACCGTCATCATTCGGTTCTGGTTACTGACCGCCATCGCCTGTGGCTTGGGCTTGGC
ACTGTTCTATGGCGAGTGGCTCGCCACGATCGGTGACTAG

Upstream 100 bases:

>100_bases
TGGCCAGTGAGCTGGCCGCGGGCGATGTGGTGCTGGTCAAGGCGTCACGGTCGGCGGGCCTCTGGGTGGTGGCCGATGAA
CTGCTGAAGGTGGGTGACGC

Downstream 100 bases:

>100_bases
GCGACCATGACCACGTGTGAAGTCGCCGAACTGACCGGCGGAACAAGGGTTCTGGTGTGCGGTGCGCGGGTCACCGGCGA
CGCCGTGGTCGCGGCGTTGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAGMWAGYFGSHLVGIAFGSDGP
SASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQLSYVREIATVA
MPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTGAYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAG
ACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQIAAFRTTGRRVFRMAPFHHHF
ELLGWAETTVIIRFWLLTAIACGLGLALFYGEWLATIGD

Sequences:

>Translated_359_residues
MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAGMWAGYFGSHLVGIAFGSDGP
SASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQLSYVREIATVA
MPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTGAYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAG
ACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQIAAFRTTGRRVFRMAPFHHHF
ELLGWAETTVIIRFWLLTAIACGLGLALFYGEWLATIGD
>Mature_359_residues
MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAGMWAGYFGSHLVGIAFGSDGP
SASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKTVGQILSALVFGVLVLQFRNTDGLTPGSPQLSYVREIATVA
MPAAIFVLFCVILVMSWSNAVNFTDGLDGLAGGCMAMVTGAYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAG
ACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQIAAFRTTGRRVFRMAPFHHHF
ELLGWAETTVIIRFWLLTAIACGLGLALFYGEWLATIGD

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=346, Percent_Identity=34.6820809248555, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_MYCA9 (B1MP34)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702739.1
- EnsemblBacteria:   EBMYCT00000006646
- GeneID:   5964517
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_2003
- GeneTree:   EBGT00050000016928
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   MABS561007:MAB_2003-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 38122; Mature: 38122

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21f244a8)-; HASH(0x23183d68)-; HASH(0x23147dc4)-; HASH(0x1fe675f0)-; HASH(0x2314cc80)-; HASH(0x2318534c)-; HASH(0x23181458)-; HASH(0x23147e48)-; HASH(0x22b45590)-; HASH(0x22a281f8)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAG
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCHHHHHHH
MWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKT
HHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
VGQILSALVFGVLVLQFRNTDGLTPGSPQLSYVREIATVAMPAAIFVLFCVILVMSWSNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNFTDGLDGLAGGCMAMVTGAYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHH
ACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFYGEWLATIGD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MRQIIIAAGIAILVSIMLTPVLIRVFSRQGFGQEIRDDGPQHHQKKRGTPSMGGVAILAG
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHCCCCCCCHHHHHHH
MWAGYFGSHLVGIAFGSDGPSASGLLVLALATMLGGVGFIDDFIKIRKARNLGLNKTSKT
HHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHH
VGQILSALVFGVLVLQFRNTDGLTPGSPQLSYVREIATVAMPAAIFVLFCVILVMSWSNA
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VNFTDGLDGLAGGCMAMVTGAYVIVTFWQYRNACSTHPGIACYNVRDPLDLAVIAAATAG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHH
ACIGFLWWNAAPAKIFMGDTGSLALGGVIAGLSVTTRTELLAVVLGALFVAEIVSVVLQI
HHHHHHHHCCCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFRTTGRRVFRMAPFHHHFELLGWAETTVIIRFWLLTAIACGLGLALFYGEWLATIGD
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA