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The map label for this gene is 169629069

Identifier: 169629069

GI number: 169629069

Start: 1979682

End: 1980953

Strand: Direct

Name: 169629069

Synonym: MAB_1982

Alternate gene names: NA

Gene position: 1979682-1980953 (Clockwise)

Preceding gene: 169629068

Following gene: 169629070

Centisome position: 39.07

GC content: 65.8

Gene sequence:

>1272_bases
GTGTCCCGTCCCGGAGACGCCGCCCCCGAGGTCCACGCACCTCCCGCAGCCACCATCGGTCTGTTCGTTGGCAAGGGGGG
CGTGGGCAAGTCGACGCTGGCCGGCGCCACCGCGGTGCGCCATGCGCGTGCCGGGCAGCGGGTATTGGCGGTATCGACCG
ACCAGGCCCATTCCCTGGGCGATGTCTTCGGTGTGCGGGTCGACCCATCCCCGGGCGCTCATTGCGTGCGGGTGATCGAG
GATCCGTACGGGGGCGAACTCGATGTCATGGCGCTGGACACTCTGGGCTTGCTGGAACGACGTTGGGGTGACATCGCCGA
CACTATTGCCGCGCAATATCCGGAATCGGATATCGGATCGCTTGCCCCCGAAGAGCTTTCCGCGTTGCCGGGCGTGCAGG
AGATGCTCGGACTGCATGAGGTGCAGCAGCTCGCCGATACGGGCGAATGGGATGTGGTGGTGGTCGACTGTGCCTCCACG
GCCGACGCCTTGCGGATGCTCACTCTCCCTGGAACTTTCGCGATGTATTTGGAGCGGGCCTGGCCTCGGCATCGCAGGCT
CGGCGGAGTCGGCACACCACGCGCGCTGATATTGGCCGAACTGCTGGAACGCATTGCGGCGTCGGCCGATCGGCTGGCTG
TCTTGCTCTCAGACGCCGAACGGGTGGGGGCTCATCTGGTGCTGACTCCCGAACGGGTGGTGGTGGCAGAGGCCATCCGC
ACCGTGGGAGCGCTGGCGCTGATGGGAGTGCGGATCGACCAAGTGATCGTCAACCAGGTTCTCATTCAAGATGATTCGTA
CGAATATCACAATCTTCCGGATCATCCCGCCTTCGACTGGTATATGCAGCGCATCACGGATCAGTCCGCCGTTCTCGACG
AGATGGGGGAGGCGATCGGAGATGTCCAAATGCTGTTGGTGCCGCATCTGCCCCGCGAACCCATCGGGCCGGACGCGCTC
GGGGAACTGGCCGAGTCGGTACGCCGCCGCGACGGCGCCAAGCCGCCCGCGCCGCTGGCAACCGTCGTCGAACATGAATC
CGGATCCGGAGCGGACACCGTCTATCGGTTGCGGCTAGAGTTACCGCAGATCGACCCGGCCACGTTGAGCCTCGGCCGGG
TGGGAGATGACCTGGTCATCGGCGCAAACGGGATGCGCCGGCGGGTCCGGCTGGCCTCCGTGCTGCGGCGCTGTGTGGTT
GTCGATGCCCGGCTCGTCGGTGGCGAGCTGACCATACGGTTCAGAGCGGATCCGGAGGTGTGGCCGACGTGA

Upstream 100 bases:

>100_bases
ATGCTCAAGCGCAAGGCCGAGCGCAAGATCACCGATTCCGCGCTCAAGGACCTGAAGAAGCGAGTCGAATCTGACCGCTA
GCGACGTCGGGGAGGAACTC

Downstream 100 bases:

>100_bases
CGGGTACTCATCCGGAGCTCGGCCCTGAGCTGCGTGCGTTGGCCACCTCGATCCTGGACAAGCTTGATCCCGCGTTGCGT
CAGGCCGCGCGTGCCGCGGC

Product: putative arsenite-transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRVLAVSTDQAHSLGDVFGVRVDPSPGAHCVRVIE
DPYGGELDVMALDTLGLLERRWGDIADTIAAQYPESDIGSLAPEELSALPGVQEMLGLHEVQQLADTGEWDVVVVDCAST
ADALRMLTLPGTFAMYLERAWPRHRRLGGVGTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIR
TVGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSAVLDEMGEAIGDVQMLLVPHLPREPIGPDAL
GELAESVRRRDGAKPPAPLATVVEHESGSGADTVYRLRLELPQIDPATLSLGRVGDDLVIGANGMRRRVRLASVLRRCVV
VDARLVGGELTIRFRADPEVWPT

Sequences:

>Translated_423_residues
MSRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRVLAVSTDQAHSLGDVFGVRVDPSPGAHCVRVIE
DPYGGELDVMALDTLGLLERRWGDIADTIAAQYPESDIGSLAPEELSALPGVQEMLGLHEVQQLADTGEWDVVVVDCAST
ADALRMLTLPGTFAMYLERAWPRHRRLGGVGTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIR
TVGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSAVLDEMGEAIGDVQMLLVPHLPREPIGPDAL
GELAESVRRRDGAKPPAPLATVVEHESGSGADTVYRLRLELPQIDPATLSLGRVGDDLVIGANGMRRRVRLASVLRRCVV
VDARLVGGELTIRFRADPEVWPT
>Mature_422_residues
SRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRVLAVSTDQAHSLGDVFGVRVDPSPGAHCVRVIED
PYGGELDVMALDTLGLLERRWGDIADTIAAQYPESDIGSLAPEELSALPGVQEMLGLHEVQQLADTGEWDVVVVDCASTA
DALRMLTLPGTFAMYLERAWPRHRRLGGVGTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIRT
VGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSAVLDEMGEAIGDVQMLLVPHLPREPIGPDALG
ELAESVRRRDGAKPPAPLATVVEHESGSGADTVYRLRLELPQIDPATLSLGRVGDDLVIGANGMRRRVRLASVLRRCVVV
DARLVGGELTIRFRADPEVWPT

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=319, Percent_Identity=25.0783699059561, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17557003, Length=254, Percent_Identity=22.0472440944882, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320103, Length=322, Percent_Identity=24.5341614906832, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24586297, Length=310, Percent_Identity=24.1935483870968, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348
- InterPro:   IPR008978 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 45401; Mature: 45269

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRVLAVSTDQAHSLG
CCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
DVFGVRVDPSPGAHCVRVIEDPYGGELDVMALDTLGLLERRWGDIADTIAAQYPESDIGS
HEEEEEECCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
LAPEELSALPGVQEMLGLHEVQQLADTGEWDVVVVDCASTADALRMLTLPGTFAMYLERA
CCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECCCHHHHHHHHH
WPRHRRLGGVGTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIR
CHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
TVGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSAVLDEMGEAIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
DVQMLLVPHLPREPIGPDALGELAESVRRRDGAKPPAPLATVVEHESGSGADTVYRLRLE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCEEEEEEEE
LPQIDPATLSLGRVGDDLVIGANGMRRRVRLASVLRRCVVVDARLVGGELTIRFRADPEV
CCCCCHHHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEECCCCC
WPT
CCC
>Mature Secondary Structure 
SRPGDAAPEVHAPPAATIGLFVGKGGVGKSTLAGATAVRHARAGQRVLAVSTDQAHSLG
CCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHH
DVFGVRVDPSPGAHCVRVIEDPYGGELDVMALDTLGLLERRWGDIADTIAAQYPESDIGS
HEEEEEECCCCCCCEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
LAPEELSALPGVQEMLGLHEVQQLADTGEWDVVVVDCASTADALRMLTLPGTFAMYLERA
CCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHEEECCCHHHHHHHHH
WPRHRRLGGVGTPRALILAELLERIAASADRLAVLLSDAERVGAHLVLTPERVVVAEAIR
CHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHH
TVGALALMGVRIDQVIVNQVLIQDDSYEYHNLPDHPAFDWYMQRITDQSAVLDEMGEAIG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
DVQMLLVPHLPREPIGPDALGELAESVRRRDGAKPPAPLATVVEHESGSGADTVYRLRLE
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHEECCCCCCCCEEEEEEEE
LPQIDPATLSLGRVGDDLVIGANGMRRRVRLASVLRRCVVVDARLVGGELTIRFRADPEV
CCCCCHHHEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEECCCCC
WPT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]