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The map label for this gene is trpD [H]

Identifier: 169629057

GI number: 169629057

Start: 1968040

End: 1969113

Strand: Direct

Name: trpD [H]

Synonym: MAB_1970

Alternate gene names: 169629057

Gene position: 1968040-1969113 (Clockwise)

Preceding gene: 169629051

Following gene: 169629060

Centisome position: 38.84

GC content: 70.2

Gene sequence:

>1074_bases
GTGTTGGAACATTCCTGGCCCCGGGTATTGGGGGAGCTGACCAACCGCCGTGACCTGACGGCGGGGCAGGCGGCCTGGGC
CATGGACCAGATCATGACGGGGACGGCCACCCCGGCACAGATCGCGGCCTTCGGGGTGTCGATGCGGATGAAGCGCCCGA
CCTCCGACGAGGTCGGGGAGCTGGCCGACACCATGCTGTCGCACGCGATCACGTTTCCGGGGGATCCGCAGGGTGCGCAG
ATCGGCGCGAACGCCGTCGACATCGTCGGCACGGGCGGTGACGGGGCCAACACGGTGAATCTGTCGACGATGGCCTCCAT
CGTCGTGGCGGCCTGCGGGGTGCCCGTGGTCAAGCACGGCAACCGCGCGGCATCCTCGCTGGCCGGCGGTGCCGACACGC
TCGAGAAGCTGGGTGTGCGCATCGACCTGGGGCCCGAGCAGGTGGTACGCAGCCTCGCCGAGGTGGGGATCGGATTCTGC
TTCGCGCCGCATTTTCATCCGTCGTATCGCTACGCCTCCGCGGTGCGCCGCGAGATCGGCGTCCCGACAGTGTTCAATCT
GCTTGGCCCGCTGACCAACCCGGCCCGTCCGCGGGCGGGTCTGATCGGATGCGCGTTCGCCGACCTGGCCGAGGTCACCG
CCGGGGTTTTCGCGGGCCGCGGCTCCAGCGTGCTGGTGGTGCACGGTGACGATGGTCTCGACGAGCTGACCACCACCACG
ACCAGCACCATCTGGCGGGTGCAGGCGGGCACCGTCGACAAGCTGCGGTTCGATCCCGCGGCCTTCGGTTTCGCGCGTGC
CCGACTGGAGGAGCTGGTCGGCGGCGATCCCGAGTTCAATGCCGCCGAGGTCCGGGCGGTGTTGGCCGGCGGCACCGGCG
CGGTCCGGGACGCGGTGCTGCTCAACGCCGCGGGTGCCATGGTCGCCCACGCCGGACTGGCCAGCGACGCCCAATGGTTA
CCCGCGTGGGAGAGCGCGCTCGCCCGGGTATCCACCGCGATCGATTCGGGAGCCGCGGCGGCATTACTGGATAGGTGGAT
AGCCGTCAGCCAGCGACTCGGGACCGGGCAGTAG

Upstream 100 bases:

>100_bases
CGAGAGCGATGCCGATGACCTGCGCCCGGCGTGTCGCGGCAGACCCGGAAGGCATTTAGTCCTTTGTTGTCTGCGTCGCC
TCCATGGGAGCATTTGCGGC

Downstream 100 bases:

>100_bases
GCGCGACCCTAGTCAGCTCGGCCATTCCCCAGTCGTCCTGGTGAAGGGCGGCCGCCATGCGCGCACTGCGTGCCGCCGCG
GCCCAATCCCGCAGCGATGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPAQIAAFGVSMRMKRPTSDEVGELADTMLSHAITFPGDPQGAQ
IGANAVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLAGGADTLEKLGVRIDLGPEQVVRSLAEVGIGFC
FAPHFHPSYRYASAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTTT
TSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLAGGTGAVRDAVLLNAAGAMVAHAGLASDAQWL
PAWESALARVSTAIDSGAAAALLDRWIAVSQRLGTGQ

Sequences:

>Translated_357_residues
MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPAQIAAFGVSMRMKRPTSDEVGELADTMLSHAITFPGDPQGAQ
IGANAVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLAGGADTLEKLGVRIDLGPEQVVRSLAEVGIGFC
FAPHFHPSYRYASAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTTT
TSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLAGGTGAVRDAVLLNAAGAMVAHAGLASDAQWL
PAWESALARVSTAIDSGAAAALLDRWIAVSQRLGTGQ
>Mature_357_residues
MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPAQIAAFGVSMRMKRPTSDEVGELADTMLSHAITFPGDPQGAQ
IGANAVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHGNRAASSLAGGADTLEKLGVRIDLGPEQVVRSLAEVGIGFC
FAPHFHPSYRYASAVRREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTTT
TSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLAGGTGAVRDAVLLNAAGAMVAHAGLASDAQWL
PAWESALARVSTAIDSGAAAALLDRWIAVSQRLGTGQ

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=32.9787234042553, Blast_Score=158, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320561, Length=330, Percent_Identity=27.8787878787879, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36831; Mature: 36831

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPAQIAAFGVSMRMKRPTSDEVGE
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCHHHHH
LADTMLSHAITFPGDPQGAQIGANAVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHG
HHHHHHHHCCCCCCCCCCCEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHCCCHHHCC
NRAASSLAGGADTLEKLGVRIDLGPEQVVRSLAEVGIGFCFAPHFHPSYRYASAVRREIG
CHHHHHHCCCHHHHHHCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
VPTVFNLLGPLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTTT
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLAGGTGAVRDAVL
HHEEEEEECCCHHHEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECCCHHHHHHHH
LNAAGAMVAHAGLASDAQWLPAWESALARVSTAIDSGAAAALLDRWIAVSQRLGTGQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLEHSWPRVLGELTNRRDLTAGQAAWAMDQIMTGTATPAQIAAFGVSMRMKRPTSDEVGE
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCCHHHHH
LADTMLSHAITFPGDPQGAQIGANAVDIVGTGGDGANTVNLSTMASIVVAACGVPVVKHG
HHHHHHHHCCCCCCCCCCCEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHCCCHHHCC
NRAASSLAGGADTLEKLGVRIDLGPEQVVRSLAEVGIGFCFAPHFHPSYRYASAVRREIG
CHHHHHHCCCHHHHHHCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
VPTVFNLLGPLTNPARPRAGLIGCAFADLAEVTAGVFAGRGSSVLVVHGDDGLDELTTTT
CCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TSTIWRVQAGTVDKLRFDPAAFGFARARLEELVGGDPEFNAAEVRAVLAGGTGAVRDAVL
HHEEEEEECCCHHHEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHEEEECCCHHHHHHHH
LNAAGAMVAHAGLASDAQWLPAWESALARVSTAIDSGAAAALLDRWIAVSQRLGTGQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA