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The map label for this gene is cysH

Identifier: 169628751

GI number: 169628751

Start: 1688935

End: 1689648

Strand: Reverse

Name: cysH

Synonym: MAB_1661c

Alternate gene names: 169628751

Gene position: 1689648-1688935 (Counterclockwise)

Preceding gene: 169628752

Following gene: 169628750

Centisome position: 33.34

GC content: 65.69

Gene sequence:

>714_bases
ATGAGCCGGGAGACAACCACCAAGGATCTCGATTCGCTGCGCGCGCTGGCCGAACGCGGCGCCGCCGAATTGCAGGACGC
TTCCGCCGAGGAGCTGCTGCGGTGGACCGACGAGAACTTCGGGGGCAACTACGTCGTCGCCTCCAACATGCAGGACGCCG
TTCTTGTCGACCTCGCCGCACAGGTGCGCCCCGGGGTGGATGTGCTGTTCCTGGACACCGGATATCACTTCGCCGAGACC
ATCGGCACCCGCGACGCGGTGGAGTCGGTGTACGACATCCACGTGGTGAACGTGGCACCCGAGCAGACGGTCGCGCAGCA
GGACGAGCTGGTGGGCAAGGACCTGTTCGCCAGCGATCCGGGCGAATGCTGCCGGTTGCGCAAGGTGGTGCCACTGCGCA
AGTCGCTCGCCGGATACGCGGCCTGGGTAACCGGTCTGCGCCGGGTCGACGCACCGACCCGCGCCAACGCGCCGTTGATC
AGCTTCGACGAGGCATTCGGGCTGGTCAAGATCAATGCGATCGCGGCGTGGACCGACGAGGACATGCAGAAGTACATCGA
TGAACACGGAACCTTGGTGAATCCGCTTGTGGACGAGGGGTATCCGTCGATCGGCTGCGCCCCGTGCACGGCCAAACCGG
TACTCGGCGGCGACGCACGAAGCGGACGCTGGCAGGGCCTTGCCAAGACAGAATGCGGGTTGCACGCCTCATGA

Upstream 100 bases:

>100_bases
GCGATTACATCGACCGGGTGGTGCGCAATTTCGTCGCGCAGCGCACCGACGGAGAGCGCTTCGCGCAGTGGGCGGTTCGC
GCTGAGGAGGCGGACTTGCG

Downstream 100 bases:

>100_bases
CGACTGAAATCGGAACGGAAGCTGTGTTGAACCAGACAGAGACACTCACCGACCTGGAATCCGAATCGATCCACATCATC
CGCGAGGTGGCCGGCGAGTT

Product: phosphoadenosine phosphosulfate reductase (CysH)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAET
IGTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPLRKSLAGYAAWVTGLRRVDAPTRANAPLI
SFDEAFGLVKINAIAAWTDEDMQKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTECGLHAS

Sequences:

>Translated_237_residues
MSRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAET
IGTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPLRKSLAGYAAWVTGLRRVDAPTRANAPLI
SFDEAFGLVKINAIAAWTDEDMQKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTECGLHAS
>Mature_236_residues
SRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAAQVRPGVDVLFLDTGYHFAETI
GTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDPGECCRLRKVVPLRKSLAGYAAWVTGLRRVDAPTRANAPLIS
FDEAFGLVKINAIAAWTDEDMQKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTECGLHAS

Specific function: Reduction of activated sulfate into sulfite

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily

Homologues:

Organism=Escherichia coli, GI1789121, Length=232, Percent_Identity=33.6206896551724, Blast_Score=108, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6325425, Length=220, Percent_Identity=30.4545454545455, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSH_MYCA9 (B1MN34)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001702400.1
- ProteinModelPortal:   B1MN34
- SMR:   B1MN34
- EnsemblBacteria:   EBMYCT00000006628
- GeneID:   5964178
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1661c
- GeneTree:   EBGT00050000017137
- HOGENOM:   HBG758022
- OMA:   FEETLAY
- BioCyc:   MABS561007:MAB_1661C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00063
- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR02055
- TIGRFAMs:   TIGR00434

Pfam domain/function: PF01507 PAPS_reduct

EC number: =1.8.4.8

Molecular weight: Translated: 25623; Mature: 25492

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAA
CCCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHH
QVRPGVDVLFLDTGYHFAETIGTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDP
HHCCCCEEEEEECCCHHHHHHCCHHHHHHHHEEEEEEECCHHHHHHHHHHHCCHHCCCCH
GECCRLRKVVPLRKSLAGYAAWVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEEECCHH
DMQKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTECGLHAS
HHHHHHHHCCCEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRETTTKDLDSLRALAERGAAELQDASAEELLRWTDENFGGNYVVASNMQDAVLVDLAA
CCCCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHH
QVRPGVDVLFLDTGYHFAETIGTRDAVESVYDIHVVNVAPEQTVAQQDELVGKDLFASDP
HHCCCCEEEEEECCCHHHHHHCCHHHHHHHHEEEEEEECCHHHHHHHHHHHCCHHCCCCH
GECCRLRKVVPLRKSLAGYAAWVTGLRRVDAPTRANAPLISFDEAFGLVKINAIAAWTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEEECCHH
DMQKYIDEHGTLVNPLVDEGYPSIGCAPCTAKPVLGGDARSGRWQGLAKTECGLHAS
HHHHHHHHCCCEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA