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The map label for this gene is mcrA [C]

Identifier: 169628657

GI number: 169628657

Start: 1597890

End: 1598441

Strand: Direct

Name: mcrA [C]

Synonym: MAB_1567

Alternate gene names: 169628657

Gene position: 1597890-1598441 (Clockwise)

Preceding gene: 169628653

Following gene: 169628658

Centisome position: 31.53

GC content: 66.12

Gene sequence:

>552_bases
ATGCCTCCGCAGCAGTCCAACGACGCCGGTTCCCTTTGGGGCCGGCGTCGCGTGTTATTGCTGAACTCCACGTATGAGCC
ACTGACCGCGTTACCGATGCGTCGAGCGGTGATCATGCTGCTGTGCGGTAAGGCCGATGTGGTGCACGACGACCCCGCTG
CCCCCATCATTCACTCCGCCACGACGTCGGTGGCGGTCCCTTCGGTGATCAGGCTGCGGACCTTCGTGCGGGTGCCGTAC
CGGGCACGGGTGCCGATGACGCGCGCCGCGCTGATGCATCGCGACCGATTCCGGTGCGCCTACTGCGGCGGACGGGCCGA
CACGATCGATCACGTGATTCCACGTAGCAAGGGCGGGGCGCACTCGTGGGAGAACTGCGTGGCGTGTTGTTCGTCCTGCA
ACCATCGCAAGGCCGACCGGCTGTTGGCGGAGCTGGGCTGGTCGCTGCACACCACCCCGATGCCGCCCAAGGGGCAACAT
TGGCGGCTGTTGTCGTCGGTCAAGGAACTGGACCCGGCATGGGTGCGATATCTAGGGGAGGGCGCGGCATGA

Upstream 100 bases:

>100_bases
GCACCGGCATAACAGTGCCAGCGCTGGGCCGACCCAAAATGGGACGGCCCGAATACTGCACAGCGTTCCGGGAGTGCCTG
AGAGCAGGATTCCTGGGGCG

Downstream 100 bases:

>100_bases
CTTCCAGGTGCGGTCGGCTACGGTTTGCATCGTGAGCTTCCTCAACAGCCCCACGTATATCGGGATGCCGGTCTGGGTAG
CCCTGATCACCCCGGTCGCC

Product: HNH endonuclease precursor

Products: NA

Alternate protein names: HNH Endonuclease Family Protein; Endonuclease; HNH Endonuclease Domain-Containing Protein; Restriction Endonuclease; HNH Endonuclease Domain Protein; Hnh Endonuclease; HNH Nuclease; McrA/HNH Family Nuclease; 5-Methylcytosine-Specific Restriction A; 5-Methylcytosine-Specific Restriction Protein; Restriction Endonuclease McrA/HNH Family; HNH EndonucleaseHNH Nuclease; HNH Family Endonuclease; LOW QUALITY PROTEIN Endonuclease; Hnh Endonuclease Domain Protein; 5-Methylcytosine-Specific Restriction Protein A

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MPPQQSNDAGSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHSATTSVAVPSVIRLRTFVRVPY
RARVPMTRAALMHRDRFRCAYCGGRADTIDHVIPRSKGGAHSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQH
WRLLSSVKELDPAWVRYLGEGAA

Sequences:

>Translated_183_residues
MPPQQSNDAGSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHSATTSVAVPSVIRLRTFVRVPY
RARVPMTRAALMHRDRFRCAYCGGRADTIDHVIPRSKGGAHSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQH
WRLLSSVKELDPAWVRYLGEGAA
>Mature_182_residues
PPQQSNDAGSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHSATTSVAVPSVIRLRTFVRVPYR
ARVPMTRAALMHRDRFRCAYCGGRADTIDHVIPRSKGGAHSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQHW
RLLSSVKELDPAWVRYLGEGAA

Specific function: Restriction Of 5-Methyl And 5-Hydroxymethylcytosines At The Specific DNA Sequence C(Me)Cgg. [C]

COG id: COG1403

COG function: function code V; Restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.21.- [C]

Molecular weight: Translated: 20344; Mature: 20213

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPQQSNDAGSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHSA
CCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCC
TTSVAVPSVIRLRTFVRVPYRARVPMTRAALMHRDRFRCAYCGGRADTIDHVIPRSKGGA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCC
HSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQHWRLLSSVKELDPAWVRYLGE
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
GAA
CCC
>Mature Secondary Structure 
PPQQSNDAGSLWGRRRVLLLNSTYEPLTALPMRRAVIMLLCGKADVVHDDPAAPIIHSA
CCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCC
TTSVAVPSVIRLRTFVRVPYRARVPMTRAALMHRDRFRCAYCGGRADTIDHVIPRSKGGA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHCCCCCCCC
HSWENCVACCSSCNHRKADRLLAELGWSLHTTPMPPKGQHWRLLSSVKELDPAWVRYLGE
CCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
GAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA