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The map label for this gene is yqeF [C]

Identifier: 169628554

GI number: 169628554

Start: 1471680

End: 1472867

Strand: Direct

Name: yqeF [C]

Synonym: MAB_1463

Alternate gene names: 169628554

Gene position: 1471680-1472867 (Clockwise)

Preceding gene: 169628552

Following gene: 169628555

Centisome position: 29.04

GC content: 66.25

Gene sequence:

>1188_bases
ATGGCCGCGACAAATAGGTCCGTAATAGTTGCTGGAGCACGTACGCCGGTTGGCCGGTTCCAGGGATCCCTGAAGGACTT
TTCCGGTGCCCAGCTCGGTGGCATCGCCATCGCGGGCGCCCTGGCGAAGGCGGGCGTGGCCCCGAGCGCAGTGGATTACG
TGATCATGGGGCAGGTGCTCACCGCCGGTGCGGGGCAGATGCCTGCACGTCAGGCGGCGGTTGCCGGTGGGATCGGCATG
GACGTCCCGGCGCTCACCATCAACAAGGTGTGCCTTTCCGGTGTGGATGCCATCGCCCTTGCTGACCAGCTGATTCGGGC
CGGCGAGTTCGAGGTGGTGGTCGCCGGTGGGCAGGAATCCATGACCAACGCACCCCACCTGCTGCCCAAGAGCCGCGCGG
GGTTCAAGTATGGGGACGTGACGCTTATCGATCACATGGCGTTCGACGGCCTGCATGACGCGTTCACCGATCAGGCCATG
GGCTTGCTGACCGAGCAGCGCAACGCCTCCGACAAATTCACCCGTGAGGAGCAGGACGAATTCGCGGCTCGTTCGCATCA
GAATGCGGCCCGCGGATGGAAGGACGGCGCCTTCGCCGACGAGGTGGTCCCGGTGCGGATTCCGCAGCGCAAGGGCGATC
CGATCGAGTTCGCCGAGGATGAGGGCATCCGGGCCGACACCACGGCTGCCTCGCTGGCCGGGCTGCGTCCGGCGTTCAGC
AAGGACGGGACCATCACTGCCGGGTCGTCGTCGCCGATCTCCGACGGTGCCTGCGCCGTCGTCGTGATGAGCAAAGAGCG
CGCGGAGCGCGAGGGGCTGGAATGGCTCGCCGAGATCGGCGCGCACGGTGTTGTCGCCGGCCCCGACTCCAGCCTGCAGC
TGCAGCCCGCCAACGCTATTCGCAAGGCATGCGAGCGGGAAGGGATTTCGCCGGAGCAGCTTGACCTGGTGGAGATCAAC
GAGGCTTTCGCGCTGGTGGGCCTGGCCTCGATCAAGGACTTGGGCATTGATCCGGAAAAGGTCAATGTCAACGGTGGTGC
GATCGCGATCGGTCACCCCATCGGAATGTCGGGTGCCCGGATCACGCTGCATCTGGCGCAAGAGCTCAAGCGCCGTGGCG
GCGGCATCGGCGTGGCGGCCTTGTGTGGCGGCGGTGGTCAGGGTGATGCCCTGATCGTCCGGGTGTGA

Upstream 100 bases:

>100_bases
AGGATCGCGGGTACATCAAGAGGAGACGAAGTCGTCATAACGCAACGGTAACCCGTTCCAGAAAACGGCGTCCAATCAAG
AAAGTTACGGAAGGACTCCC

Downstream 100 bases:

>100_bases
TTTACGACGTGTTGTAGTAGATAGGCATTGCGCCGGGCACCGCATCGGGCAGACTGAGGGCATGACACAGCTTTTCGACC
TGCGGAGCACTGCAAGCAGG

Product: acetyl-CoA acetyltransferase FadA

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAATNRSVIVAGARTPVGRFQGSLKDFSGAQLGGIAIAGALAKAGVAPSAVDYVIMGQVLTAGAGQMPARQAAVAGGIGM
DVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQESMTNAPHLLPKSRAGFKYGDVTLIDHMAFDGLHDAFTDQAM
GLLTEQRNASDKFTREEQDEFAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTAASLAGLRPAFS
KDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEIGAHGVVAGPDSSLQLQPANAIRKACEREGISPEQLDLVEIN
EAFALVGLASIKDLGIDPEKVNVNGGAIAIGHPIGMSGARITLHLAQELKRRGGGIGVAALCGGGGQGDALIVRV

Sequences:

>Translated_395_residues
MAATNRSVIVAGARTPVGRFQGSLKDFSGAQLGGIAIAGALAKAGVAPSAVDYVIMGQVLTAGAGQMPARQAAVAGGIGM
DVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQESMTNAPHLLPKSRAGFKYGDVTLIDHMAFDGLHDAFTDQAM
GLLTEQRNASDKFTREEQDEFAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTAASLAGLRPAFS
KDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEIGAHGVVAGPDSSLQLQPANAIRKACEREGISPEQLDLVEIN
EAFALVGLASIKDLGIDPEKVNVNGGAIAIGHPIGMSGARITLHLAQELKRRGGGIGVAALCGGGGQGDALIVRV
>Mature_394_residues
AATNRSVIVAGARTPVGRFQGSLKDFSGAQLGGIAIAGALAKAGVAPSAVDYVIMGQVLTAGAGQMPARQAAVAGGIGMD
VPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQESMTNAPHLLPKSRAGFKYGDVTLIDHMAFDGLHDAFTDQAMG
LLTEQRNASDKFTREEQDEFAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTAASLAGLRPAFSK
DGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEIGAHGVVAGPDSSLQLQPANAIRKACEREGISPEQLDLVEINE
AFALVGLASIKDLGIDPEKVNVNGGAIAIGHPIGMSGARITLHLAQELKRRGGGIGVAALCGGGGQGDALIVRV

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=395, Percent_Identity=44.0506329113924, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=41.5384615384615, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI167614485, Length=397, Percent_Identity=41.3098236775819, Blast_Score=264, Evalue=8e-71,
Organism=Homo sapiens, GI4501853, Length=393, Percent_Identity=37.9134860050891, Blast_Score=214, Evalue=7e-56,
Organism=Homo sapiens, GI4504327, Length=421, Percent_Identity=32.7790973871734, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI194353979, Length=389, Percent_Identity=27.7634961439589, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI19923233, Length=365, Percent_Identity=25.7534246575342, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI302344760, Length=345, Percent_Identity=24.9275362318841, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI302344767, Length=322, Percent_Identity=24.5341614906832, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87082165, Length=386, Percent_Identity=45.3367875647668, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788554, Length=388, Percent_Identity=45.360824742268, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1787663, Length=395, Percent_Identity=36.7088607594937, Blast_Score=232, Evalue=4e-62,
Organism=Escherichia coli, GI48994986, Length=393, Percent_Identity=36.6412213740458, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1788683, Length=414, Percent_Identity=31.8840579710145, Blast_Score=184, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI25147385, Length=392, Percent_Identity=41.0714285714286, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI133906874, Length=385, Percent_Identity=41.2987012987013, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17535921, Length=392, Percent_Identity=37.5, Blast_Score=257, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI17535917, Length=397, Percent_Identity=34.0050377833753, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551802, Length=421, Percent_Identity=30.6413301662708, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6325229, Length=391, Percent_Identity=43.7340153452685, Blast_Score=301, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6322031, Length=395, Percent_Identity=35.6962025316456, Blast_Score=202, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24640423, Length=387, Percent_Identity=43.4108527131783, Blast_Score=306, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24655093, Length=387, Percent_Identity=45.2196382428941, Blast_Score=304, Evalue=6e-83,
Organism=Drosophila melanogaster, GI17648125, Length=395, Percent_Identity=38.4810126582278, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI17137578, Length=421, Percent_Identity=31.8289786223278, Blast_Score=172, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40630; Mature: 40498

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATNRSVIVAGARTPVGRFQGSLKDFSGAQLGGIAIAGALAKAGVAPSAVDYVIMGQVL
CCCCCCCEEEEECCCCHHHHHCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
TAGAGQMPARQAAVAGGIGMDVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQES
HCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHH
MTNAPHLLPKSRAGFKYGDVTLIDHMAFDGLHDAFTDQAMGLLTEQRNASDKFTREEQDE
CCCCCCCCCCCCCCCEECCEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTAASLAGLRPAFS
HHHHHCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
KDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEIGAHGVVAGPDSSLQLQPANAI
CCCCEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHH
RKACEREGISPEQLDLVEINEAFALVGLASIKDLGIDPEKVNVNGGAIAIGHPIGMSGAR
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCCCCE
ITLHLAQELKRRGGGIGVAALCGGGGQGDALIVRV
EEHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEC
>Mature Secondary Structure 
AATNRSVIVAGARTPVGRFQGSLKDFSGAQLGGIAIAGALAKAGVAPSAVDYVIMGQVL
CCCCCCEEEEECCCCHHHHHCCHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
TAGAGQMPARQAAVAGGIGMDVPALTINKVCLSGVDAIALADQLIRAGEFEVVVAGGQES
HCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHH
MTNAPHLLPKSRAGFKYGDVTLIDHMAFDGLHDAFTDQAMGLLTEQRNASDKFTREEQDE
CCCCCCCCCCCCCCCEECCEEEEHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
FAARSHQNAARGWKDGAFADEVVPVRIPQRKGDPIEFAEDEGIRADTTAASLAGLRPAFS
HHHHHCCHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCC
KDGTITAGSSSPISDGACAVVVMSKERAEREGLEWLAEIGAHGVVAGPDSSLQLQPANAI
CCCCEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCCEEECCHHHH
RKACEREGISPEQLDLVEINEAFALVGLASIKDLGIDPEKVNVNGGAIAIGHPIGMSGAR
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCCCCCCCCE
ITLHLAQELKRRGGGIGVAALCGGGGQGDALIVRV
EEHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA