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The map label for this gene is 169628550

Identifier: 169628550

GI number: 169628550

Start: 1468488

End: 1470095

Strand: Reverse

Name: 169628550

Synonym: MAB_1459c

Alternate gene names: NA

Gene position: 1470095-1468488 (Counterclockwise)

Preceding gene: 169628553

Following gene: 169628547

Centisome position: 29.01

GC content: 64.43

Gene sequence:

>1608_bases
ATGGCAAACGAGTCGATTCGCGCAGTGTCGCGGCGGGTGGGCCGTGCGTTGGGCGCGATTACAGGACAGACCGGAAACAT
CAACACCGGCAATGGCTACGGTTCCTGGCTGCTCGGGACGGCCGACGAGAGCACATTCATCCAGCGGATCCGAATCCAGC
TGATCCTGACCGTGTTTGTGGTGGCCGCCAATCTCATCGGGATCGGCGTGGTGATTTTGCTAGTGACGGTGGCGTTCCCC
ACCCCCAACGTCTTCGACGCACCGGCCTGGGTCAACTTCGTCATAGTCCCCGTCTACATCGCCCTCGCCGTCCTCATCGG
CGCCGTCTGGGGCACCCGGCGCATCTTCAAAGCAGTGCGGTGGGCATTGGACGAGCGCCCACCCACCAAGGCCGACCAGC
GCAACGCCTTCGCTGTGCCGTGGCGTCTCACCGTCATACAGTCGGTGTTGTGGGCAGGTGGCGTGGCGTTATTCACGCTG
CTTTACGGGCTCTATGACCCCATGTACATCCCCAAGATCTTCTTCGCCGTCGGCTTCAGTGGCGCGGTGGTCTGCGCCGC
CAACTATCTGTTCACCGAGTTCGCGATGCGACCCGTCGCCGCACGCGCGCTCGAGGCAGGCTATCGCCGACGCAGGCTGG
CTTCGGGGGTGATGGTGCGGACGGTGCTTGCCTGGATGCTGGGATCCGGAGTGCCCGCGGCGGGCATCGTGATCACCGGC
ATCGGCGCCCTGGTACTACACAACCTCACGGTGAGCCAGCTCGCGGTGGCGGTGATCATCATCGCCGGCGCGATTCCGTC
TTTCGGGCTCATCCTGATCTGGATCGCGTCATGGTTGATGGCTACGCCGGTGAAGGAAGTCCAGACCGCGATCAAGCGGG
TCGCCCAAAATGACCTCGACATCGATCTCGTCGTCTACGACGGCACCGAGCTCGGCGAGCTGCAGGCCGGTTTCAACACC
ATGGTGGAGGGCCTGCGCGAACGAGAGCGGGTCAGGGACCTCTTCGGCAAGCATGTGGGTCGCGAGGTAGCGGCGGCCGC
CGAGCAGCAACAGCCCGAGCTTGGGGGCGAAGAACGCCATATCGCAGTGCTTTTCGCCGATATTGTCGGTTCAACCCGCC
TCGCGGCGACCCGCCCCGCAGTCGAGGTCGTCGCGCTGCTCAACCGGTTCTTTACCGTCGTCGTCGAAGAGATCGACCGA
TACGAAGGCATGGTCAACAAGTTCGAAGGTGATGCGACCCTCGCGGTGTTCGGCGCACCGGTCCGGCAGGACCGCCCCGA
GAGCCAAGCCCTTGCCGCCGCACGCGCCATTGCCCGCCGTCTCCGTACCGAGGTGCCCGAATGTCAGGCCGGAATCGGAG
TCGCCTCCGGACAGGCCGTAGCGGGAAACATCGGCGCTCATGACCGCTTCGAGTACACCGTCATCGGAGATCCGGTCAAT
GAGGCTGCCCGACTCTGCGAACTGTCCAAGACGGTGCCCGGACACCTGGTGGCCTCACTCGACACCGTGCTGCGCGCACA
CCATCGTGAAGCCCTGCATTGGCGTTCCGGCGATACGGTGACGCTGCGCGGACGCACCGAACCCACCGAACTCGCGGTGC
CTGTTTAG

Upstream 100 bases:

>100_bases
ATGGCAGGTGGGCGGTCAGCCGGCCAACATAATTAACGGTGCACTGAGCAACGACGAGACGCACCGGCCCACTGTATAGG
GCGTTAGGCTGGCAACAACT

Downstream 100 bases:

>100_bases
TCGGACTGTTTCCACCACGCCTCGACGTAGAGCACCATCGCCACCACCAGCGCGATGAGCACCCACAGCACGAGAGCCTG
ATCGATCCATGCCCCCGGCG

Product: hypothetical protein

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLGTADESTFIQRIRIQLILTVFVVAANLIGIGVVILLVTVAFP
TPNVFDAPAWVNFVIVPVYIALAVLIGAVWGTRRIFKAVRWALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTL
LYGLYDPMYIPKIFFAVGFSGAVVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVPAAGIVITG
IGALVLHNLTVSQLAVAVIIIAGAIPSFGLILIWIASWLMATPVKEVQTAIKRVAQNDLDIDLVVYDGTELGELQAGFNT
MVEGLRERERVRDLFGKHVGREVAAAAEQQQPELGGEERHIAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDR
YEGMVNKFEGDATLAVFGAPVRQDRPESQALAAARAIARRLRTEVPECQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVN
EAARLCELSKTVPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV

Sequences:

>Translated_535_residues
MANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLGTADESTFIQRIRIQLILTVFVVAANLIGIGVVILLVTVAFP
TPNVFDAPAWVNFVIVPVYIALAVLIGAVWGTRRIFKAVRWALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTL
LYGLYDPMYIPKIFFAVGFSGAVVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVPAAGIVITG
IGALVLHNLTVSQLAVAVIIIAGAIPSFGLILIWIASWLMATPVKEVQTAIKRVAQNDLDIDLVVYDGTELGELQAGFNT
MVEGLRERERVRDLFGKHVGREVAAAAEQQQPELGGEERHIAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDR
YEGMVNKFEGDATLAVFGAPVRQDRPESQALAAARAIARRLRTEVPECQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVN
EAARLCELSKTVPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV
>Mature_534_residues
ANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLGTADESTFIQRIRIQLILTVFVVAANLIGIGVVILLVTVAFPT
PNVFDAPAWVNFVIVPVYIALAVLIGAVWGTRRIFKAVRWALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTLL
YGLYDPMYIPKIFFAVGFSGAVVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVPAAGIVITGI
GALVLHNLTVSQLAVAVIIIAGAIPSFGLILIWIASWLMATPVKEVQTAIKRVAQNDLDIDLVVYDGTELGELQAGFNTM
VEGLRERERVRDLFGKHVGREVAAAAEQQQPELGGEERHIAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDRY
EGMVNKFEGDATLAVFGAPVRQDRPESQALAAARAIARRLRTEVPECQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVNE
AARLCELSKTVPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 57780; Mature: 57649

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLGTADESTFIQRIRIQLILTVFV
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
VAANLIGIGVVILLVTVAFPTPNVFDAPAWVNFVIVPVYIALAVLIGAVWGTRRIFKAVR
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WALDERPPTKADQRNAFAVPWRLTVIQSVLWAGGVALFTLLYGLYDPMYIPKIFFAVGFS
HHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
GAVVCAANYLFTEFAMRPVAARALEAGYRRRRLASGVMVRTVLAWMLGSGVPAAGIVITG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
IGALVLHNLTVSQLAVAVIIIAGAIPSFGLILIWIASWLMATPVKEVQTAIKRVAQNDLD
HHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
IDLVVYDGTELGELQAGFNTMVEGLRERERVRDLFGKHVGREVAAAAEQQQPELGGEERH
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IAVLFADIVGSTRLAATRPAVEVVALLNRFFTVVVEEIDRYEGMVNKFEGDATLAVFGAP
EEEEEHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
VRQDRPESQALAAARAIARRLRTEVPECQAGIGVASGQAVAGNIGAHDRFEYTVIGDPVN
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCEEECCCCCCCCEEEEEECCCHH
EAARLCELSKTVPGHLVASLDTVLRAHHREALHWRSGDTVTLRGRTEPTELAVPV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
ANESIRAVSRRVGRALGAITGQTGNINTGNGYGSWLLGTADESTFIQRIRIQLILTVFV
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH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HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]