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The map label for this gene is rho [H]

Identifier: 169628529

GI number: 169628529

Start: 1443495

End: 1445435

Strand: Direct

Name: rho [H]

Synonym: MAB_1438

Alternate gene names: 169628529

Gene position: 1443495-1445435 (Clockwise)

Preceding gene: 169628528

Following gene: 169628532

Centisome position: 28.49

GC content: 65.69

Gene sequence:

>1941_bases
GTGACCGATACGGACCTCATCGCGACCGAAGCCGCCCCGGAAACTCCGGAGGCGCCCGCCGCAGCCTCATCCGACCGCGC
CGGTAAGGAGCGCCGGGGTGACGGACTGGGCGCGCTGTCGACGATGGTGCTTCCGGAGCTGCGCGCGCTGGCCAGTCAGG
TAGGCGTGAAGGGCACCTCCGGGATGCGTAAGGGCGACTTGATCGCCGCCATTCGCGAGCATCAGGGCGCGCTTGGTGCG
CCGAAGAACAACAATCAGGCGGCGCAGAGCCAGCAGCCGCAGGCCTCGTCGGCACCGGCGGAGGCGCCACAGAAGGAATC
GGGCCAGAAGGAATCGGGCCAGAAGGAATCGGGCCTGAAGGAATCGGCTGAGCCGACCCAGACCGCGCTCGATCTTCCTG
CCGAGGCACCGAAGCCCGTGGCCGAATCCACGCAGGACTCCGAGGGGAAGAAGGCCGAGAACGGCGCGGCCCCCCGTGAG
GGACGTGGTGAGCGGCGTCGCAACCAGAACCAGAACCAGAACCAACCGGCCGAGGGCGAGCGCAAGCAGAACGGCAGCCG
CGACAACGCCGACAACGCTGAGAGCTCCGGTCGTGATGGCGGCTCCAGTGGCCAGAACTCGGACAACCAGAACCAGGACA
CCAACCAGAACCAGGGCAATCGCGGCGATGACGGCGAGGGCCGCGGCCGCCGTGGGCGTCGCACCCGGGAGCGTCGTCGC
GGTCGCGATCGCAACAACAACGAGGGCGGCGAGACCGAACTGCGCGAGGACGATGTCGTCCAGCCGGTGGCCGGAATTCT
CGATGTGCTGGACAACTACGCGTTCGTCCGTACGTCCGGCTACCTGGCCGGCCCCAACGATGTCTACGTCTCGATGAATC
TGGTGCGCAAGAACGGGCTGCGTCGTGGTGACGCCATCACCGGCGCGGTGCGCGTACCCCGCGATCCTGACGCCGGTAAT
CAGAATCAGCGGCAGAAGTTCAACCCGTTGGTGCGCCTGGACTCCGTCAACGGCGGCCCGGTCGAGGACGCCAAGAAGCG
TCCCGATTTCACCAAGCTGACCCCGCTGTACCCGAACCAGCGTCTGCGGTTGGAGACGACCACCGAGAAGCTCACGACTC
GTGTGATCGACCTGATCATGCCGATCGGCAAGGGGCAGCGTGCGTTGATCGTTTCGCCGCCCAAGGCCGGTAAGACCACG
ATCATGCAGAACATCGCCAATGCGATCTCGGCCAACAACCCCGAATGCCACCTCATGGTGGTGCTCGTGGACGAACGGCC
CGAAGAAGTCACCGACATGCAGCGCTCGGTTAAGGGCGAGGTCATCGCCTCGACCTTCGACCGTCCGCCGTCAGATCACA
CCCAGGCTGCCGAGCTAGCCATCGAGCGCGCCAAGCGCCTGGTGGAACAGGGCAAGGACGTCGTGGTGCTGTTGGACTCG
ATCACCCGTCTGGGTCGTGCGTACAACAACGCGTCGCCGGCCTCGGGACGCATCTTGTCCGGTGGTGTCGACTCGACCGC
GCTGTACCCGCCCAAGCGATTCCTCGGCGCGGCGCGCAACATCGAGAACGGTGGCTCCCTGACGATCATCGCCACGGCCA
TGGTCGAGACCGGCTCCACCGGTGACACCGTCATCTTCGAGGAGTTCAAGGGGACGGGTAACGCCGAGCTCAAGCTCGAT
CGCAAGATCGCCGAGCGCCGGGTGTTCCCCGCCGTCGACGTCAACCCGTCGGGTACCCGCAAGGACGAGCTGCTGATGAG
CGGCGACGAGTTCGCGATCGTGCACAAGCTGCGTCGGGTGCTGTCCGGACTCGATTCGCATCAGGCCATCGATCTGCTGA
TGAGCCAGCTGCGCAAGACAAAGAACAACTACGAGTTCCTGGTCCAAGTGTCCAAGAACACCCCGGGCGCCGCCGGCGCC
GAGGAGACGCAGTACAGCTAA

Upstream 100 bases:

>100_bases
TATCTGTGTGGGCCCGCAGCATGAACTTCGCGGCCAGCAACCTAACTGGCCGAAGTGAGACCCCTCGCCCCATGTTTGGC
GGGGGAAGGAAAGGAAATCC

Downstream 100 bases:

>100_bases
CGCGTCGGGTCACTGATATGGATCGGTGATCTCCCGCAGCGGCGCCAGTACCTCGACCGTGTGCTCGTAGTGCTCGTACG
GCATGGCGCCCACGTGTTGT

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MTDTDLIATEAAPETPEAPAAASSDRAGKERRGDGLGALSTMVLPELRALASQVGVKGTSGMRKGDLIAAIREHQGALGA
PKNNNQAAQSQQPQASSAPAEAPQKESGQKESGQKESGLKESAEPTQTALDLPAEAPKPVAESTQDSEGKKAENGAAPRE
GRGERRRNQNQNQNQPAEGERKQNGSRDNADNAESSGRDGGSSGQNSDNQNQDTNQNQGNRGDDGEGRGRRGRRTRERRR
GRDRNNNEGGETELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGLRRGDAITGAVRVPRDPDAGN
QNQRQKFNPLVRLDSVNGGPVEDAKKRPDFTKLTPLYPNQRLRLETTTEKLTTRVIDLIMPIGKGQRALIVSPPKAGKTT
IMQNIANAISANNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDS
ITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLD
RKIAERRVFPAVDVNPSGTRKDELLMSGDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGAAGA
EETQYS

Sequences:

>Translated_646_residues
MTDTDLIATEAAPETPEAPAAASSDRAGKERRGDGLGALSTMVLPELRALASQVGVKGTSGMRKGDLIAAIREHQGALGA
PKNNNQAAQSQQPQASSAPAEAPQKESGQKESGQKESGLKESAEPTQTALDLPAEAPKPVAESTQDSEGKKAENGAAPRE
GRGERRRNQNQNQNQPAEGERKQNGSRDNADNAESSGRDGGSSGQNSDNQNQDTNQNQGNRGDDGEGRGRRGRRTRERRR
GRDRNNNEGGETELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGLRRGDAITGAVRVPRDPDAGN
QNQRQKFNPLVRLDSVNGGPVEDAKKRPDFTKLTPLYPNQRLRLETTTEKLTTRVIDLIMPIGKGQRALIVSPPKAGKTT
IMQNIANAISANNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDS
ITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLD
RKIAERRVFPAVDVNPSGTRKDELLMSGDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGAAGA
EETQYS
>Mature_645_residues
TDTDLIATEAAPETPEAPAAASSDRAGKERRGDGLGALSTMVLPELRALASQVGVKGTSGMRKGDLIAAIREHQGALGAP
KNNNQAAQSQQPQASSAPAEAPQKESGQKESGQKESGLKESAEPTQTALDLPAEAPKPVAESTQDSEGKKAENGAAPREG
RGERRRNQNQNQNQPAEGERKQNGSRDNADNAESSGRDGGSSGQNSDNQNQDTNQNQGNRGDDGEGRGRRGRRTRERRRG
RDRNNNEGGETELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGLRRGDAITGAVRVPRDPDAGNQ
NQRQKFNPLVRLDSVNGGPVEDAKKRPDFTKLTPLYPNQRLRLETTTEKLTTRVIDLIMPIGKGQRALIVSPPKAGKTTI
MQNIANAISANNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDSI
TRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDR
KIAERRVFPAVDVNPSGTRKDELLMSGDEFAIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGAAGAE
ETQYS

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=369, Percent_Identity=55.2845528455285, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1788251, Length=287, Percent_Identity=26.1324041811847, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 69664; Mature: 69533

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTDLIATEAAPETPEAPAAASSDRAGKERRGDGLGALSTMVLPELRALASQVGVKGTS
CCCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GMRKGDLIAAIREHQGALGAPKNNNQAAQSQQPQASSAPAEAPQKESGQKESGQKESGLK
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHCCCC
ESAEPTQTALDLPAEAPKPVAESTQDSEGKKAENGAAPREGRGERRRNQNQNQNQPAEGE
CCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCH
RKQNGSRDNADNAESSGRDGGSSGQNSDNQNQDTNQNQGNRGDDGEGRGRRGRRTRERRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
GRDRNNNEGGETELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEECCCCCEEEEEEEHHHCCC
RRGDAITGAVRVPRDPDAGNQNQRQKFNPLVRLDSVNGGPVEDAKKRPDFTKLTPLYPNQ
CCCCCCCCEEECCCCCCCCCCCHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
RLRLETTTEKLTTRVIDLIMPIGKGQRALIVSPPKAGKTTIMQNIANAISANNPECHLMV
EEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
VLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDS
EEECCCCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHH
ITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIATAMVETGST
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEECCCC
GDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLMSGDEFAIVHKLRRV
CCEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHH
LSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGAAGAEETQYS
HHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDTDLIATEAAPETPEAPAAASSDRAGKERRGDGLGALSTMVLPELRALASQVGVKGTS
CCCCEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GMRKGDLIAAIREHQGALGAPKNNNQAAQSQQPQASSAPAEAPQKESGQKESGQKESGLK
CCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCHHCCCCCCCCHHCCCC
ESAEPTQTALDLPAEAPKPVAESTQDSEGKKAENGAAPREGRGERRRNQNQNQNQPAEGE
CCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCH
RKQNGSRDNADNAESSGRDGGSSGQNSDNQNQDTNQNQGNRGDDGEGRGRRGRRTRERRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHC
GRDRNNNEGGETELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEECCEECCCCCEEEEEEEHHHCCC
RRGDAITGAVRVPRDPDAGNQNQRQKFNPLVRLDSVNGGPVEDAKKRPDFTKLTPLYPNQ
CCCCCCCCEEECCCCCCCCCCCHHHHCCCEEEEECCCCCCCCHHHCCCCCCCCCCCCCCC
RLRLETTTEKLTTRVIDLIMPIGKGQRALIVSPPKAGKTTIMQNIANAISANNPECHLMV
EEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEE
VLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTQAAELAIERAKRLVEQGKDVVVLLDS
EEECCCCHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHH
ITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIATAMVETGST
HHHHHHHHCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEECCCC
GDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLMSGDEFAIVHKLRRV
CCEEEEECCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHEECCCCHHHHHHHHHH
LSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKNTPGAAGAEETQYS
HHCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]