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The map label for this gene is ykuT [H]

Identifier: 169628502

GI number: 169628502

Start: 1414440

End: 1415459

Strand: Direct

Name: ykuT [H]

Synonym: MAB_1411

Alternate gene names: 169628502

Gene position: 1414440-1415459 (Clockwise)

Preceding gene: 169628496

Following gene: 169628503

Centisome position: 27.91

GC content: 64.71

Gene sequence:

>1020_bases
ATGTCAGACCTTGCGATTCAACTGTCAGAGTCCGGTCGGGATTGGCTGATCCACAGGCCGGTCGACATCGCCATCTACGT
CGTTTTGGCGCTCGCGGTTCGGTACGTGTTGCATCGGGCGATCGACCGCCTGGTGCAAGGCGCGAGGCGGCCGGAATCTG
CAGAACATCCCCGACGGCAGTGGTGGGCGTTCCTGCGTCGCGGACGTGATCTGGGGGAGAGTGATCGTCTGGACGAGACC
GCGCGGCTGCCAGCGAGGACGCGCACGCTGCGAGGGCGCGCACAGGACCCGGCTCGCGATGCGCGCAGGCGGAAGCGGCG
GGCGCAGCGAGCGCAGACCCTCGGGTCGGTTCTCAAGTCGGCGGTCTCGTTTTTGGTGCTGGTCTGGGTGATCCTGCAAT
CGCTGGCGATCCTGGGAGTGAACGTCGCACCCTTCATCGCATCCGCGGGCATCGTCGGCGTTGCGCTTGGCTTCGGCGCG
CAAAACTTGGTGCGGGACTTCATTACCGGAATATTCATGCTGTTCGAGGACCAGTATGGGGTGGGCGACGTAGTGGATGT
CGGTGACGCCGTCGGCACCGTCGAGAGTGTCGGGCTGCGGATTACCACGGTGCGTGACCTGCAAGGCACGCTTTGGTACG
TGCGCAACGGGGGGATCGCGCGGGTGGGCAATTTCAGTCAGGACTATGCGGTGGCATTTCTGCAGATACCCCTTTCCTAC
AGCGCCGACGTGGATCTGGCCTGCACGATTGCACTCGAGGCCGCCCGGGAGGCGGTCGCCGAGGAAGCCCTGCGCGACGA
CGTCATTGGGGCCCCGGAGATGCTAGGCATCGACGGCATCACCGCGGACGCAATCAGTCTGCGGTTGACGGTGGCGGTCC
GTGCGAACGCGCAGTGGGCCGTGGAACGTGAATTGCGGCGCCGCATCCTCATCGCATTCGACGAGAACGGCATCCGCCCG
CTCTACCTGGATGGATTGTCGAGCGGCACCGTCGAAACCCTTGAGAAAGCGAGCCGGTAG

Upstream 100 bases:

>100_bases
GACGAATTGCGCACAGGGCAAACATTTTTCGTGTCGCGGGAATGAGTCGACCGATATTTGCCCACTCGCGTGATCGGGGT
AAATGGGTACCCTCGGGGAG

Downstream 100 bases:

>100_bases
CCTGCGCCCACGCGCAGTACGCTGGTGACATGGCTGGTAAGGAAATCGACAAGCAGCGGGCAAACGCCGCGCTGGCGGTG
ATCCGGCTGCATCCGGGAAT

Product: putative mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHRAIDRLVQGARRPESAEHPRRQWWAFLRRGRDLGESDRLDET
ARLPARTRTLRGRAQDPARDARRRKRRAQRAQTLGSVLKSAVSFLVLVWVILQSLAILGVNVAPFIASAGIVGVALGFGA
QNLVRDFITGIFMLFEDQYGVGDVVDVGDAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAFLQIPLSY
SADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITADAISLRLTVAVRANAQWAVERELRRRILIAFDENGIRP
LYLDGLSSGTVETLEKASR

Sequences:

>Translated_339_residues
MSDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHRAIDRLVQGARRPESAEHPRRQWWAFLRRGRDLGESDRLDET
ARLPARTRTLRGRAQDPARDARRRKRRAQRAQTLGSVLKSAVSFLVLVWVILQSLAILGVNVAPFIASAGIVGVALGFGA
QNLVRDFITGIFMLFEDQYGVGDVVDVGDAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAFLQIPLSY
SADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITADAISLRLTVAVRANAQWAVERELRRRILIAFDENGIRP
LYLDGLSSGTVETLEKASR
>Mature_338_residues
SDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHRAIDRLVQGARRPESAEHPRRQWWAFLRRGRDLGESDRLDETA
RLPARTRTLRGRAQDPARDARRRKRRAQRAQTLGSVLKSAVSFLVLVWVILQSLAILGVNVAPFIASAGIVGVALGFGAQ
NLVRDFITGIFMLFEDQYGVGDVVDVGDAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAFLQIPLSYS
ADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITADAISLRLTVAVRANAQWAVERELRRRILIAFDENGIRPL
YLDGLSSGTVETLEKASR

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=222, Percent_Identity=31.5315315315315, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 37324; Mature: 37193

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHRAIDRLVQGARRPESAEHPRRQ
CCCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
WWAFLRRGRDLGESDRLDETARLPARTRTLRGRAQDPARDARRRKRRAQRAQTLGSVLKS
HHHHHHHCCCCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVSFLVLVWVILQSLAILGVNVAPFIASAGIVGVALGFGAQNLVRDFITGIFMLFEDQYG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
VGDVVDVGDAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAFLQIPLSY
CCCHHHCCHHHHHHHHCCEEEEEEECCCCEEEEEECCCEEECCCCCHHHEEEEEEECCCC
SADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITADAISLRLTVAVRANAQWA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEEECCCHHH
VERELRRRILIAFDENGIRPLYLDGLSSGTVETLEKASR
HHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SDLAIQLSESGRDWLIHRPVDIAIYVVLALAVRYVLHRAIDRLVQGARRPESAEHPRRQ
CCCEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
WWAFLRRGRDLGESDRLDETARLPARTRTLRGRAQDPARDARRRKRRAQRAQTLGSVLKS
HHHHHHHCCCCCCCCCCCHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVSFLVLVWVILQSLAILGVNVAPFIASAGIVGVALGFGAQNLVRDFITGIFMLFEDQYG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
VGDVVDVGDAVGTVESVGLRITTVRDLQGTLWYVRNGGIARVGNFSQDYAVAFLQIPLSY
CCCHHHCCHHHHHHHHCCEEEEEEECCCCEEEEEECCCEEECCCCCHHHEEEEEEECCCC
SADVDLACTIALEAAREAVAEEALRDDVIGAPEMLGIDGITADAISLRLTVAVRANAQWA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCEEEEEEEEEECCCHHH
VERELRRRILIAFDENGIRPLYLDGLSSGTVETLEKASR
HHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]