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The map label for this gene is ampC [C]

Identifier: 169628478

GI number: 169628478

Start: 1383259

End: 1384539

Strand: Direct

Name: ampC [C]

Synonym: MAB_1387

Alternate gene names: 169628478

Gene position: 1383259-1384539 (Clockwise)

Preceding gene: 169628477

Following gene: 169628482

Centisome position: 27.3

GC content: 65.89

Gene sequence:

>1281_bases
ATGGCACAACCTCATGGCCTCGATGACGCGGCCACGGAATTACCGCTACCGGCGCGGCCGCAATTCGCCTACCCTCCGCT
GGAACGCGGTATGGAGCTACCGCCGGGAGTGAACGGTTGGGCGCGCCCCGAGTTCCGCGGAGTAGTGCGCGTCTTCGCGT
TCGCCTTCACCCGTTATCGCGTGGGTGGGGGCGCCGCGTGCGTGTACGTGGATGGTGAGCCCGTGCTCGACCTGTGGGCT
GGGGTGGCGCAGAAGGGTGAGGAGTGGACTCGTGATACCGCTCCGGTGATCTTCTCGGCGTCCAAGGGAGTGACCGCGAC
GATCATTCACCGTCTGGTGGATCGTGGACTGTTGGACTACCGCGCGCCGGTGGCGCGGTACTGGCCGGAGTTTGCCGCCA
ACGGCAAGGAAGCGATCACGGTCGATGGGATTCTCTCGCACACCGCGGGTCTGTCGCGGCTTACCGGCATTGCGCACAAC
TACGAGGAGATGTTCGATCCGGATCTGATGGCCGATCGCCTGGCCGCGGCTCCGGTCGATAGATATTTCGGCAAGCCGGC
CTACCACGCTCTGTCTATTGGCTGGCTGATGGGACGGCTGGCCAAAGCCGTCACCGGTAGGGATTTGGAGGAGCTGTACC
GCAGCGAGCTGGCCGAGCCGCTGGGTGTCGACGGCATCTACATGGGACGCCCGCCGGCCGGTGCTCCGTCGCAATCTGCT
GCGCTCACACCGTATTTGGACCGGGTCGCACGGTCTGGCTTCATCCGTCGCGCTGCCCCTTCCGTGATGGGTGTGCTCGA
CAAGATGCCCGGCGCCAAGGGCGCCGCGTCGACGCTGTACCAGCCGGGCGCGGAAATGCTGCTCGCTGACGACGGGCACG
CCAGCGCCGCGGTGATGGACCTGCGGTGTGGTGCGGGCAGCGCATGTTGCACCGCGCCGGCGCTGGCCAAGCTGTACGCT
GCGCTGGCCGGCGATGGCAGCGTGGATGGTGTGCGTCTACTGTCGCCGGACATCACCCGCGGACTGGGGCGCAAGAACAG
CTATCGGATCGACCACACGCTCGGGCTTCCGATGGGTTGGCACCGTGGGTATCACTCGCTGACGGCCCCCGTGATCGGTG
GCGGCTTCGGCCATATCGGTGCCGGCGGATCCTTCGGGTGGGCCGACCAGAAACGCAAAATCTCGGTGGCCATTGTGCAC
AACCGGCTTCCCCGCACGATGGTGTTCGATCAAACCGTCATCGGTACCTTCCTGCCGTCAATCATTCGCGCCGCGCGGTA
A

Upstream 100 bases:

>100_bases
GTGAAGCGCCCCCAATCGCTGCGCCCCGATTGGGTATCTGTCTGACATCTACGCCATCGCGCTTGCCTTGATGTCGAGTA
CCTGGTACTCACTGTTACTT

Downstream 100 bases:

>100_bases
CGCGGCGCAAATGATCGGCCCGGGTTACTTCTTACCCGGCCGGGGCAGGATGAAGCGGGTCACCACGGAGAAGATGTCCT
GGTAACGGGCACCGGTGAGC

Product: putative esterase/lipase/beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: Esterase; Carboxylesterase; Beta-Lactamase Class C; Esterase/Lipase LipP; Esterase A; Esterase/Lipase/Beta-Lactamase; Lactone Hydrolase; Lipase LipE; Beta-Lactamase Protein; Esterase LipL; Lipase LipD; Lipase/Esterase/Beta-Lactamase; Beta-Lactamase Family Protein; Hydrolase; Esterase/Lipase; Carboxylesterase EstC; Serine Hydrolase; Beta-Lactamase Family

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAQPHGLDDAATELPLPARPQFAYPPLERGMELPPGVNGWARPEFRGVVRVFAFAFTRYRVGGGAACVYVDGEPVLDLWA
GVAQKGEEWTRDTAPVIFSASKGVTATIIHRLVDRGLLDYRAPVARYWPEFAANGKEAITVDGILSHTAGLSRLTGIAHN
YEEMFDPDLMADRLAAAPVDRYFGKPAYHALSIGWLMGRLAKAVTGRDLEELYRSELAEPLGVDGIYMGRPPAGAPSQSA
ALTPYLDRVARSGFIRRAAPSVMGVLDKMPGAKGAASTLYQPGAEMLLADDGHASAAVMDLRCGAGSACCTAPALAKLYA
ALAGDGSVDGVRLLSPDITRGLGRKNSYRIDHTLGLPMGWHRGYHSLTAPVIGGGFGHIGAGGSFGWADQKRKISVAIVH
NRLPRTMVFDQTVIGTFLPSIIRAAR

Sequences:

>Translated_426_residues
MAQPHGLDDAATELPLPARPQFAYPPLERGMELPPGVNGWARPEFRGVVRVFAFAFTRYRVGGGAACVYVDGEPVLDLWA
GVAQKGEEWTRDTAPVIFSASKGVTATIIHRLVDRGLLDYRAPVARYWPEFAANGKEAITVDGILSHTAGLSRLTGIAHN
YEEMFDPDLMADRLAAAPVDRYFGKPAYHALSIGWLMGRLAKAVTGRDLEELYRSELAEPLGVDGIYMGRPPAGAPSQSA
ALTPYLDRVARSGFIRRAAPSVMGVLDKMPGAKGAASTLYQPGAEMLLADDGHASAAVMDLRCGAGSACCTAPALAKLYA
ALAGDGSVDGVRLLSPDITRGLGRKNSYRIDHTLGLPMGWHRGYHSLTAPVIGGGFGHIGAGGSFGWADQKRKISVAIVH
NRLPRTMVFDQTVIGTFLPSIIRAAR
>Mature_425_residues
AQPHGLDDAATELPLPARPQFAYPPLERGMELPPGVNGWARPEFRGVVRVFAFAFTRYRVGGGAACVYVDGEPVLDLWAG
VAQKGEEWTRDTAPVIFSASKGVTATIIHRLVDRGLLDYRAPVARYWPEFAANGKEAITVDGILSHTAGLSRLTGIAHNY
EEMFDPDLMADRLAAAPVDRYFGKPAYHALSIGWLMGRLAKAVTGRDLEELYRSELAEPLGVDGIYMGRPPAGAPSQSAA
LTPYLDRVARSGFIRRAAPSVMGVLDKMPGAKGAASTLYQPGAEMLLADDGHASAAVMDLRCGAGSACCTAPALAKLYAA
LAGDGSVDGVRLLSPDITRGLGRKNSYRIDHTLGLPMGWHRGYHSLTAPVIGGGFGHIGAGGSFGWADQKRKISVAIVHN
RLPRTMVFDQTVIGTFLPSIIRAAR

Specific function: This Protein Is A Serine Beta-Lactamase With A Substrate Specificity For Cephalosporins. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI71983659, Length=407, Percent_Identity=29.2383292383292, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71983666, Length=210, Percent_Identity=36.1904761904762, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17538474, Length=378, Percent_Identity=27.5132275132275, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17538001, Length=378, Percent_Identity=28.042328042328, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17535177, Length=391, Percent_Identity=26.5984654731458, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17535191, Length=388, Percent_Identity=25, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990590, Length=394, Percent_Identity=23.8578680203046, Blast_Score=98, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 45489; Mature: 45357

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQPHGLDDAATELPLPARPQFAYPPLERGMELPPGVNGWARPEFRGVVRVFAFAFTRYR
CCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
VGGGAACVYVDGEPVLDLWAGVAQKGEEWTRDTAPVIFSASKGVTATIIHRLVDRGLLDY
ECCCEEEEEECCCHHHHHHHHHHHCCHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
RAPVARYWPEFAANGKEAITVDGILSHTAGLSRLTGIAHNYEEMFDPDLMADRLAAAPVD
CCHHHHHCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
RYFGKPAYHALSIGWLMGRLAKAVTGRDLEELYRSELAEPLGVDGIYMGRPPAGAPSQSA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
ALTPYLDRVARSGFIRRAAPSVMGVLDKMPGAKGAASTLYQPGAEMLLADDGHASAAVMD
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCEEEEE
LRCGAGSACCTAPALAKLYAALAGDGSVDGVRLLSPDITRGLGRKNSYRIDHTLGLPMGW
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCCH
HRGYHSLTAPVIGGGFGHIGAGGSFGWADQKRKISVAIVHNRLPRTMVFDQTVIGTFLPS
HCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
IIRAAR
HHHHCC
>Mature Secondary Structure 
AQPHGLDDAATELPLPARPQFAYPPLERGMELPPGVNGWARPEFRGVVRVFAFAFTRYR
CCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHE
VGGGAACVYVDGEPVLDLWAGVAQKGEEWTRDTAPVIFSASKGVTATIIHRLVDRGLLDY
ECCCEEEEEECCCHHHHHHHHHHHCCHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
RAPVARYWPEFAANGKEAITVDGILSHTAGLSRLTGIAHNYEEMFDPDLMADRLAAAPVD
CCHHHHHCHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHH
RYFGKPAYHALSIGWLMGRLAKAVTGRDLEELYRSELAEPLGVDGIYMGRPPAGAPSQSA
HHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCC
ALTPYLDRVARSGFIRRAAPSVMGVLDKMPGAKGAASTLYQPGAEMLLADDGHASAAVMD
CCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCCCCEEEEE
LRCGAGSACCTAPALAKLYAALAGDGSVDGVRLLSPDITRGLGRKNSYRIDHTLGLPMGW
EECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCCEEEEEEECCCCCH
HRGYHSLTAPVIGGGFGHIGAGGSFGWADQKRKISVAIVHNRLPRTMVFDQTVIGTFLPS
HCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
IIRAAR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA