Click here to switch to the map view.

The map label for this gene is galE [C]

Identifier: 169628437

GI number: 169628437

Start: 1345489

End: 1346466

Strand: Reverse

Name: galE [C]

Synonym: MAB_1344c

Alternate gene names: 169628437

Gene position: 1346466-1345489 (Counterclockwise)

Preceding gene: 169628440

Following gene: 169628430

Centisome position: 26.57

GC content: 65.85

Gene sequence:

>978_bases
ATGAGCGAGAGGCGATTCCTGGTCACCGGATCCTCGGGACATCTGGGTGAGGCACTGGTCCGCACGCTGCGGCGGGACGG
CGTCGATGTCGTGGGAATCGATATCGCCGCGGGCCCGGCCACCGATATCGTCGGGTCGATCGCCGACCGTGGCCTGGTGG
CTGAGGCGATGAGCGGGATGACCTCGGTACTGCACACCGCGACACTGCACAAGCCGCATATCGGGTCGCACCCGCGCACC
GATTTCGTCGAGACCAATATTGAAGGCACGCTGTCCGTGCTGGAGGCGGCGGTTGCGGCGGGGGTACGCAGCTTTGTGTA
CACCAGCACAACCAGCGCCTTCGGTCATGCGCTGGTCGGGGCGCGCGAGGCGGCCTGGATCACCGAAGCCGTGGCCTCGG
TGCCCAAGAACATCTATGGGGCCACCAAGACCGCAGCCGAGGACATCGCGCATGTAGTGCATCAGGACAGCGGCCTACCG
GTGATCGTGCTGCGCACCTCGCGGTTCTTCCCCGAGCAGGACGACAACGACCGGGTGCGCAACCGCTACCGCGACGGCAA
CGTGAAGGCCAACGAGTACCTGTACCGGCGAGTGGATCTGGCCGATGTGGTCGACGCGCACCTGCTGGCCGCCGAACGCG
GACCCGAGATCGGCTGGGCCAAGTACGTGATCTCGGCGACAACACCCTTCAGCCCGGGCGATGCCGCGCAGCTACGGACC
GATCCGGGAGCCGTGGTGGCTCGTTACTTCCCGGAGCAGCCTGGCCTGTACGCGGCACGCGGATGGTCCATGTTCCCGAC
GATCGACAGGGTCTACGTCAACGCCAGGGCCCGCGACGATCTCGGCTGGCAACCACGGTACGACTACCGTCGCATCCTCG
ATTGTCTTGCCGCGGAACAAGATTTCCGCAGTCCGCTGGCGCGCGAGATAGGCGCAAAGGGATATCACGACGAGCCGACG
GGCGTGTACACCACCTAG

Upstream 100 bases:

>100_bases
TGCGCCGAGTGTGAAGCTGCTGCGGGATTTGGACCGATTTCCCGCAACGGCTTCACTCTCGGCACGCGAAATGACTTGCG
GGCCTCGGCAGTATGGGCAC

Downstream 100 bases:

>100_bases
GCCAGCGCCTGAGTGACCTCCACATATCGACGCAGAAACGCCGTCTCGTCAAGACGTTTGCGCCGCATCCAGCTGGTCAC
CTCGGCATTGCATTTGCTGG

Product: putative dTDP-glucose-4,6-dehydratase-related protein

Products: UDPgalactose

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MSERRFLVTGSSGHLGEALVRTLRRDGVDVVGIDIAAGPATDIVGSIADRGLVAEAMSGMTSVLHTATLHKPHIGSHPRT
DFVETNIEGTLSVLEAAVAAGVRSFVYTSTTSAFGHALVGAREAAWITEAVASVPKNIYGATKTAAEDIAHVVHQDSGLP
VIVLRTSRFFPEQDDNDRVRNRYRDGNVKANEYLYRRVDLADVVDAHLLAAERGPEIGWAKYVISATTPFSPGDAAQLRT
DPGAVVARYFPEQPGLYAARGWSMFPTIDRVYVNARARDDLGWQPRYDYRRILDCLAAEQDFRSPLAREIGAKGYHDEPT
GVYTT

Sequences:

>Translated_325_residues
MSERRFLVTGSSGHLGEALVRTLRRDGVDVVGIDIAAGPATDIVGSIADRGLVAEAMSGMTSVLHTATLHKPHIGSHPRT
DFVETNIEGTLSVLEAAVAAGVRSFVYTSTTSAFGHALVGAREAAWITEAVASVPKNIYGATKTAAEDIAHVVHQDSGLP
VIVLRTSRFFPEQDDNDRVRNRYRDGNVKANEYLYRRVDLADVVDAHLLAAERGPEIGWAKYVISATTPFSPGDAAQLRT
DPGAVVARYFPEQPGLYAARGWSMFPTIDRVYVNARARDDLGWQPRYDYRRILDCLAAEQDFRSPLAREIGAKGYHDEPT
GVYTT
>Mature_324_residues
SERRFLVTGSSGHLGEALVRTLRRDGVDVVGIDIAAGPATDIVGSIADRGLVAEAMSGMTSVLHTATLHKPHIGSHPRTD
FVETNIEGTLSVLEAAVAAGVRSFVYTSTTSAFGHALVGAREAAWITEAVASVPKNIYGATKTAAEDIAHVVHQDSGLPV
IVLRTSRFFPEQDDNDRVRNRYRDGNVKANEYLYRRVDLADVVDAHLLAAERGPEIGWAKYVISATTPFSPGDAAQLRTD
PGAVVARYFPEQPGLYAARGWSMFPTIDRVYVNARARDDLGWQPRYDYRRILDCLAAEQDFRSPLAREIGAKGYHDEPTG
VYTT

Specific function: Putative nucleotide sugar epimerase/dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 5.1.3.2

Molecular weight: Translated: 35411; Mature: 35280

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERRFLVTGSSGHLGEALVRTLRRDGVDVVGIDIAAGPATDIVGSIADRGLVAEAMSGM
CCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHH
TSVLHTATLHKPHIGSHPRTDFVETNIEGTLSVLEAAVAAGVRSFVYTSTTSAFGHALVG
HHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
AREAAWITEAVASVPKNIYGATKTAAEDIAHVVHQDSGLPVIVLRTSRFFPEQDDNDRVR
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHH
NRYRDGNVKANEYLYRRVDLADVVDAHLLAAERGPEIGWAKYVISATTPFSPGDAAQLRT
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEECC
DPGAVVARYFPEQPGLYAARGWSMFPTIDRVYVNARARDDLGWQPRYDYRRILDCLAAEQ
CCCHHHHHHCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
DFRSPLAREIGAKGYHDEPTGVYTT
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SERRFLVTGSSGHLGEALVRTLRRDGVDVVGIDIAAGPATDIVGSIADRGLVAEAMSGM
CCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHH
TSVLHTATLHKPHIGSHPRTDFVETNIEGTLSVLEAAVAAGVRSFVYTSTTSAFGHALVG
HHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
AREAAWITEAVASVPKNIYGATKTAAEDIAHVVHQDSGLPVIVLRTSRFFPEQDDNDRVR
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHH
NRYRDGNVKANEYLYRRVDLADVVDAHLLAAERGPEIGWAKYVISATTPFSPGDAAQLRT
HHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEECC
DPGAVVARYFPEQPGLYAARGWSMFPTIDRVYVNARARDDLGWQPRYDYRRILDCLAAEQ
CCCHHHHHHCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
DFRSPLAREIGAKGYHDEPTGVYTT
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDP-glucose

Specific reaction: UDP-glucose = UDP-galactose

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]