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The map label for this gene is mmpL3 [H]

Identifier: 169628380

GI number: 169628380

Start: 1291513

End: 1293726

Strand: Direct

Name: mmpL3 [H]

Synonym: MAB_1287

Alternate gene names: 169628380

Gene position: 1291513-1293726 (Clockwise)

Preceding gene: 169628375

Following gene: 169628381

Centisome position: 25.49

GC content: 63.28

Gene sequence:

>2214_bases
ATGATGCTCGAACGTTTGGCTCGATCGGTGATCGCGGCGCCCCGCCTCGTTCTCGGGATGGCGCTGCTCATCGCGATCGC
GGCGGCCCTCTTCGGCGTTCCGGTGACCAAGCATCTGGCCGCCGGTGGTCAGCAAGACCCGAACTCCGAATCTGCCTATG
TGACCAAGGCTCTCCGAGACAAGTTTGATATCAGCGACCAGTCTCTGGTCTTCATGCTCACCAGCGAACAAGGCGTCAAG
AGCCCGCAGATGCGTGCCGTCGCAGCAGATCTGGAGCGCCAGCTCAAAGACTCCGGCGTGGTCATCAACCTGACCTCGGC
CTGGACGGCGCCGCCACAGGTAGCCGAGGAACTGCTGGGCGCCGATGGCAAGGCCGGATTGATCGTCGCCGGGCTGACCG
GGGGCGAGAACGACGCGCAGAAGCACGCGGCAAAGCTCATCAAGTCTCTCGCGGTGGACCGTGACGGGGTAGCGGTCAAG
GCCGGCGGTGTCGCCACGCTCTACAACCAGATCGTCACCCAGTCCGAGAAGGACCTGCTGGTTATGGAGTCGATCGCGAT
TCCGATCAGCTTTGTGGTGTTGGTATGGATATTCGGCGGCCTCTACGCGGCCCTGTTGCCTCTCGTAGTCGGAGTGTTTT
CCATCGTCGGCGCCATGTCGATATTGCGCGGGCTGACGTATGTCACCGATGTGTCCGTGTTCGCGCTGAACCTTGCGGTG
GCAATGGGATTGGCGCTGGCGATCGACTACTCCCTGCTGATCATCAGTCGCTATCGCGAGGAGGTGAATGCGGGCAAACC
GCGCGATGAAGCGCTGGTCCTGACCATGACCACGGCCGGACGGACCGTGCTGTTCTCGGCGCTGACGGTTGCGCTGGCCC
TGGTAGCGCTGATCCTGTTCCCGATGTACTTCCTCAAATCGTTCGGATACGCCGGTGTAGCCGTCGTCTTCGTTGGCGCC
ATCGCCGCGCTGGTCATCGTCCCGGCGGTAGTCACCCTGCTGGGCGACCGGATCGACGCCCTGGACGTGCGCCGCCTGAT
CCGCAGGGTCCTGGGAAGGCCGGAACCCGTCGCCAAGGACGTCACGCAAAGCTTCTGGTACCGGACCACCAAAAGGGTTA
TGGCGCGCGCTGTTCCGATTGCCATCATCATCGTCAGCGCATTGGTGGTGCTGGGCCTGCCGTTCCTCGACGGCAAGTTC
GGATTCCCGGATGACCGGGTCTTGCCCGCCTCGGCCTCGGCGCATCAAGTCGGCAACGAGATGCGCCGCAACTTCAACAA
CAACAGCTCCACCAACTTGTCCGTCATCGCCGAGGGCGTCGGTTCGGTGCCGCCGAGGGAGATCGACGAGTACGCCGCGG
ACCTGTCGAATATCGAGGACGTCAAGGAGGTGGCCGCACCCACCGGTGCGTTCATCCGGGGCATGAAGGTGGGCCCGTCG
GCAAGTGCAACCGGAATCAAGAATGACACAGCACTTTTCACGGTTCAGACCGCCGCCAAGCCGTACACGGAGGCCGCCGA
GCGCCAGCTCGATGCCATCCACGCACTGCCGGGCCCGGCCGATGTCTTGGTCAGGATCGGCGGGGGAGCCCAGTTGGATC
GTGACGCCGTCGACGGCATTGTGCACAAGCTGCCCCTGGTGCTGGCCATCATCGCCGTCGTCACCTTTGTGCTGCTATTT
CTGCTAACGGGTTCGGTGGTACTGCCTATCAAAGCGTTGGTCCTCAACGTGCTGTCGTTGACGGCCACCTTCGGCGCGCT
GATCTGGATCTTCCAGGAGGGACACCTGGGCGGGTTCGGCACCGAGGTCACCGGCACCATCGTCGCCACCATGCCGATGC
TGTTGTTCTGCATAGCTTTTGGGCTATCAATGGACTATGAGGTGTTTCTCATCTCGCGCATCCGCGAGTACTGGATGGCC
TCCGGGCGCACCCGGGCCGACAACGACGAGGCGGTGGCGCTCGGTGTGGCCCGCACCGGCCGGGTGGTCACCGCCGCGGC
GCTGATCATGGCGATCGCCTTCGCGGCACTGATGGCTGCGCAGGTGTCCTTCATGCGGATGTTCGGTACCGGACTGACCA
TCGCGATCCTGGTGGACGCCACCATCATCCGGATGCTGCTGGTGCCGTCGTTCATGCGGCTGCTGGGACGGTTCAACTGG
TGGGCGCCCAAGCCGTTGGTCACGCTGCATGAACGGATCGGATTCAGTGACTAG

Upstream 100 bases:

>100_bases
ATTTCTCTCACCACCTAAGCGGCGCATCCGCCTCAACCACCCTTGACCGTCTAACTTATCGCTGATAACTTAACGCCGTT
ATTCTCCGGCGGAAGGCGCG

Downstream 100 bases:

>100_bases
GCGGCAGCGCGCGTCCCGCGGCTCGGGCGATCGACTGCGCGACGAAATAATCGACGCCGCAATCGCTCTTGTTTTGGAGA
CCAAGGAATTGCGTGCACCG

Product: MmpL family membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSESAYVTKALRDKFDISDQSLVFMLTSEQGVK
SPQMRAVAADLERQLKDSGVVINLTSAWTAPPQVAEELLGADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAVK
AGGVATLYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYAGVAVVFVGA
IAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKDVTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGKF
GFPDDRVLPASASAHQVGNEMRRNFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPS
ASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLF
LLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMA
SGRTRADNDEAVALGVARTGRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNW
WAPKPLVTLHERIGFSD

Sequences:

>Translated_737_residues
MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSESAYVTKALRDKFDISDQSLVFMLTSEQGVK
SPQMRAVAADLERQLKDSGVVINLTSAWTAPPQVAEELLGADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAVK
AGGVATLYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYAGVAVVFVGA
IAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKDVTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGKF
GFPDDRVLPASASAHQVGNEMRRNFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPS
ASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLF
LLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMA
SGRTRADNDEAVALGVARTGRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNW
WAPKPLVTLHERIGFSD
>Mature_737_residues
MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSESAYVTKALRDKFDISDQSLVFMLTSEQGVK
SPQMRAVAADLERQLKDSGVVINLTSAWTAPPQVAEELLGADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAVK
AGGVATLYNQIVTQSEKDLLVMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVALALVALILFPMYFLKSFGYAGVAVVFVGA
IAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKDVTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGKF
GFPDDRVLPASASAHQVGNEMRRNFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPS
ASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGIVHKLPLVLAIIAVVTFVLLF
LLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFGTEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMA
SGRTRADNDEAVALGVARTGRVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNW
WAPKPLVTLHERIGFSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 78448; Mature: 78448

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSESAYVTKALRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
KFDISDQSLVFMLTSEQGVKSPQMRAVAADLERQLKDSGVVINLTSAWTAPPQVAEELLG
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHC
ADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCH
VMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVALALVALILF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHH
VTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MRRNFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPS
HHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
ASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCHHHHHHH
VHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
TEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMASGRTRADNDEAVALGVARTG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCC
RVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WAPKPLVTLHERIGFSD
CCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MMLERLARSVIAAPRLVLGMALLIAIAAALFGVPVTKHLAAGGQQDPNSESAYVTKALRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHH
KFDISDQSLVFMLTSEQGVKSPQMRAVAADLERQLKDSGVVINLTSAWTAPPQVAEELLG
HCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHC
ADGKAGLIVAGLTGGENDAQKHAAKLIKSLAVDRDGVAVKAGGVATLYNQIVTQSEKDLL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHCCCCCCH
VMESIAIPISFVVLVWIFGGLYAALLPLVVGVFSIVGAMSILRGLTYVTDVSVFALNLAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMGLALAIDYSLLIISRYREEVNAGKPRDEALVLTMTTAGRTVLFSALTVALALVALILF
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PMYFLKSFGYAGVAVVFVGAIAALVIVPAVVTLLGDRIDALDVRRLIRRVLGRPEPVAKD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHH
VTQSFWYRTTKRVMARAVPIAIIIVSALVVLGLPFLDGKFGFPDDRVLPASASAHQVGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
MRRNFNNNSSTNLSVIAEGVGSVPPREIDEYAADLSNIEDVKEVAAPTGAFIRGMKVGPS
HHHCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
ASATGIKNDTALFTVQTAAKPYTEAAERQLDAIHALPGPADVLVRIGGGAQLDRDAVDGI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCHHHHHHH
VHKLPLVLAIIAVVTFVLLFLLTGSVVLPIKALVLNVLSLTATFGALIWIFQEGHLGGFG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
TEVTGTIVATMPMLLFCIAFGLSMDYEVFLISRIREYWMASGRTRADNDEAVALGVARTG
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHCC
RVVTAAALIMAIAFAALMAAQVSFMRMFGTGLTIAILVDATIIRMLLVPSFMRLLGRFNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WAPKPLVTLHERIGFSD
CCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]