Click here to switch to the map view.

The map label for this gene is engD [H]

Identifier: 169628359

GI number: 169628359

Start: 1270405

End: 1271478

Strand: Direct

Name: engD [H]

Synonym: MAB_1266

Alternate gene names: 169628359

Gene position: 1270405-1271478 (Clockwise)

Preceding gene: 169628357

Following gene: 169628360

Centisome position: 25.07

GC content: 64.62

Gene sequence:

>1074_bases
GTGAGCCTGAACCTGGGAATCGTCGGTCTGCCGAACGTCGGGAAGTCGACGCTATTCAATGCGCTGACCCGCAATAACGT
GCTGGCGGCCAACTACCCGTTTGCGACCATCGAGCCGAACGAGGGCGTGGTGCCGCTGCCCGACCCGCGTCTGGACAAGC
TGGCCGAGGTGTTCGGTTCGGCGCGCACGCTGCCCGCCACGGTGACGTTCGTGGACATCGCCGGAATCGTCAAGGGTGCC
TCCGAGGGGGCCGGGCTGGGAAACAAGTTCCTGGCGAACATCCGCGAATGTGACGCCATCTGTCAGGTGGTGCGAGTGTT
CGCCGACGACGACGTGGTGCACGTCGACGGGCGGGTCGATCCTGCCGCCGATATCGAGGTGATCGAGACCGAGCTGATTC
TCGCCGATATGCAGACGCTGGAGAAGGCGGTGCCGCGGCTGGAGAAGGAAGCCAAGAACAAGAAGGACCGCCAGCCGCTG
CTCGATGCCGCCAAGGCCGCGCAGGAGGTGCTCGACGGGGGCAAGACGCTGTTCTCGACAGGTAAAGACTGGTCGTCGGT
GCGCGAACTGAACCTGATGACCACCAAGCCGTTCTTGTATGTGTTCAACGCCGACGAGTCGGTGCTGGGGGACGAGGCAC
GGGTGGCGCAGCTGCGTGCGTTGGTGGCCCCTGCCGACGCGGTGTTCCTGGACGCCAAGATCGAGTCCGAGCTGCAGGAG
CTGGACGAGGAGTCTGCCGCCGAGCTGCTGGAGTCGATCGGGCAGGCCGAGCGTGGCCTGGATGCCTTGGCGCGGGCAGG
CTTTCACACGCTGAAGTTGCAGACCTACCTGACCGCCGGGCCAAAAGAGGCGCGCGCGTGGACGATTCACCAGGGCGACA
CCGCGCCCAAGGCGGCCGGCGTCATCCACACCGACTTCGAGAAGGGCTTCATCAAGGCCGAGGTGGTGTCCTACGAGGAC
CTCATCGAGGCCGGATCGATGGCTGCGGCCAAGGCCGCCGGAAAGGTCCGGATGGAAGGCAAGGAATACGTCATGGTTGA
CGGTGACGTGGTGGAATTCCGGTTTAACGTCTAG

Upstream 100 bases:

>100_bases
CGCGATAGCCGTCGGAGGGGTCGGGGGACTCGTAGATCCGCTTGGTGGAAAAGGTCACCGCACCATTCTTAATCGCCGCG
GTCCGTAGACTCTCCATCTC

Downstream 100 bases:

>100_bases
GCGGAAGCGCTACTAATGCCGCGCCGCCGCGAACTTCGGGACGTCTGCCAGGGAGTCGCGACGAGTTTCGGCAGTCGGAA
CAACGACATTGCAGGTTGGT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVPLPDPRLDKLAEVFGSARTLPATVTFVDIAGIVKGA
SEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADMQTLEKAVPRLEKEAKNKKDRQPL
LDAAKAAQEVLDGGKTLFSTGKDWSSVRELNLMTTKPFLYVFNADESVLGDEARVAQLRALVAPADAVFLDAKIESELQE
LDEESAAELLESIGQAERGLDALARAGFHTLKLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFEKGFIKAEVVSYED
LIEAGSMAAAKAAGKVRMEGKEYVMVDGDVVEFRFNV

Sequences:

>Translated_357_residues
MSLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVPLPDPRLDKLAEVFGSARTLPATVTFVDIAGIVKGA
SEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADMQTLEKAVPRLEKEAKNKKDRQPL
LDAAKAAQEVLDGGKTLFSTGKDWSSVRELNLMTTKPFLYVFNADESVLGDEARVAQLRALVAPADAVFLDAKIESELQE
LDEESAAELLESIGQAERGLDALARAGFHTLKLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFEKGFIKAEVVSYED
LIEAGSMAAAKAAGKVRMEGKEYVMVDGDVVEFRFNV
>Mature_356_residues
SLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVPLPDPRLDKLAEVFGSARTLPATVTFVDIAGIVKGAS
EGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGRVDPAADIEVIETELILADMQTLEKAVPRLEKEAKNKKDRQPLL
DAAKAAQEVLDGGKTLFSTGKDWSSVRELNLMTTKPFLYVFNADESVLGDEARVAQLRALVAPADAVFLDAKIESELQEL
DEESAAELLESIGQAERGLDALARAGFHTLKLQTYLTAGPKEARAWTIHQGDTAPKAAGVIHTDFEKGFIKAEVVSYEDL
IEAGSMAAAKAAGKVRMEGKEYVMVDGDVVEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=44.0540540540541, Blast_Score=294, Evalue=7e-80,
Organism=Homo sapiens, GI58761502, Length=186, Percent_Identity=40.8602150537634, Blast_Score=137, Evalue=1e-32,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=51.2396694214876, Blast_Score=364, Evalue=1e-102,
Organism=Escherichia coli, GI1789574, Length=129, Percent_Identity=32.5581395348837, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.4371584699454, Blast_Score=270, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=40, Blast_Score=249, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=35.8839050131926, Blast_Score=218, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=153, Percent_Identity=35.9477124183007, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=42.5474254742547, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=42.5474254742547, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=42.5474254742547, Blast_Score=279, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24640879, Length=327, Percent_Identity=40.3669724770642, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24585318, Length=139, Percent_Identity=31.6546762589928, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38439; Mature: 38308

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVPLPDPRLDKLAEVFGS
CCCCCEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEECCCCCHHHHHHHHHCC
ARTLPATVTFVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGRVD
CCCCCEEEEHEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PAADIEVIETELILADMQTLEKAVPRLEKEAKNKKDRQPLLDAAKAAQEVLDGGKTLFST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECC
GKDWSSVRELNLMTTKPFLYVFNADESVLGDEARVAQLRALVAPADAVFLDAKIESELQE
CCCHHHHHHEEEEEECCEEEEECCCCHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
LDEESAAELLESIGQAERGLDALARAGFHTLKLQTYLTAGPKEARAWTIHQGDTAPKAAG
HCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCCC
VIHTDFEKGFIKAEVVSYEDLIEAGSMAAAKAAGKVRMEGKEYVMVDGDVVEFRFNV
EEEECCCCCCEEEEHCCHHHHHHHCCHHHHHHCCCEEECCCEEEEECCCEEEEEECC
>Mature Secondary Structure 
SLNLGIVGLPNVGKSTLFNALTRNNVLAANYPFATIEPNEGVVPLPDPRLDKLAEVFGS
CCCCEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEECCCCCHHHHHHHHHCC
ARTLPATVTFVDIAGIVKGASEGAGLGNKFLANIRECDAICQVVRVFADDDVVHVDGRVD
CCCCCEEEEHEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
PAADIEVIETELILADMQTLEKAVPRLEKEAKNKKDRQPLLDAAKAAQEVLDGGKTLFST
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECC
GKDWSSVRELNLMTTKPFLYVFNADESVLGDEARVAQLRALVAPADAVFLDAKIESELQE
CCCHHHHHHEEEEEECCEEEEECCCCHHHCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHH
LDEESAAELLESIGQAERGLDALARAGFHTLKLQTYLTAGPKEARAWTIHQGDTAPKAAG
HCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCCC
VIHTDFEKGFIKAEVVSYEDLIEAGSMAAAKAAGKVRMEGKEYVMVDGDVVEFRFNV
EEEECCCCCCEEEEHCCHHHHHHHCCHHHHHHCCCEEECCCEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]