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The map label for this gene is algU [H]

Identifier: 169628341

GI number: 169628341

Start: 1256350

End: 1256925

Strand: Direct

Name: algU [H]

Synonym: MAB_1248

Alternate gene names: 169628341

Gene position: 1256350-1256925 (Clockwise)

Preceding gene: 169628333

Following gene: 169628342

Centisome position: 24.79

GC content: 63.54

Gene sequence:

>576_bases
GTGGTGCTGCCGCTCTTGCCTCGGGGCGAACTACTGGCGTCGTTGTCGGACGAGATGCTTGCTCGACGCGCTCAGCAAGG
TGATTCCGAGGCGTTCGATGTTCTGGTCGTCCGGCATGGCCCCGCGCTGCTGAGATTCGTTGCCCGCACGTATCCGGAGC
GGGCCGAGTATGACGACATCGTCCAGGAGACGTTCATCGCCGCATGGAAAGGGCTGCCGTCCTTTGCCTTTCGGTCCCAG
TTCCGAACCTGGTTGTATTCGCTCGCCTCCCGGAAAACCGTTGACGCCATGCGGCGGCGCCGTCGCGACTTCGATATCGA
CGAAGTACCTGAAGTTGCCGATGCCGGCGCGGGGCCCAGTGAACGCGCCTTGGACGGTGATTTCCTTGCGGCGTTGAGCC
GCGAGCTGTCGCAGCTGCCCTATGCGGCGCGTGCGGCCTGGTGGTTACGTGAGGTTTATGACCTACCTCTGGCGGAGATA
GCGACTGTTCTTCGGACCACTGAGGGCTCGGTTCGCGGCAACTTGCAGCGCACCCGCAAGCGGCTCGCGGAGACGCTTAA
GGACTTCCGCCCGTGA

Upstream 100 bases:

>100_bases
CATTTTTGTCCGGCACAATGAGTTCGTCGGGCAACGGTGGGAACTGCGCACGCCGACGAGACCTAACACACATTTCGTAC
TCGCGACGACAGGGGACACA

Downstream 100 bases:

>100_bases
GTGAACGCGCAGATCACATTCAATCCGCCCGCTGTACAGCTTCCGGCATATGGCGTAACACTGGAGACCTGATGGATGCG
AGAAACGGGGACAATCACGA

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MVLPLLPRGELLASLSDEMLARRAQQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDIVQETFIAAWKGLPSFAFRSQ
FRTWLYSLASRKTVDAMRRRRRDFDIDEVPEVADAGAGPSERALDGDFLAALSRELSQLPYAARAAWWLREVYDLPLAEI
ATVLRTTEGSVRGNLQRTRKRLAETLKDFRP

Sequences:

>Translated_191_residues
MVLPLLPRGELLASLSDEMLARRAQQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDIVQETFIAAWKGLPSFAFRSQ
FRTWLYSLASRKTVDAMRRRRRDFDIDEVPEVADAGAGPSERALDGDFLAALSRELSQLPYAARAAWWLREVYDLPLAEI
ATVLRTTEGSVRGNLQRTRKRLAETLKDFRP
>Mature_191_residues
MVLPLLPRGELLASLSDEMLARRAQQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDIVQETFIAAWKGLPSFAFRSQ
FRTWLYSLASRKTVDAMRRRRRDFDIDEVPEVADAGAGPSERALDGDFLAALSRELSQLPYAARAAWWLREVYDLPLAEI
ATVLRTTEGSVRGNLQRTRKRLAETLKDFRP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=183, Percent_Identity=32.7868852459016, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21754; Mature: 21754

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPLLPRGELLASLSDEMLARRAQQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDI
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
VQETFIAAWKGLPSFAFRSQFRTWLYSLASRKTVDAMRRRRRDFDIDEVPEVADAGAGPS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
ERALDGDFLAALSRELSQLPYAARAAWWLREVYDLPLAEIATVLRTTEGSVRGNLQRTRK
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
RLAETLKDFRP
HHHHHHHHCCC
>Mature Secondary Structure
MVLPLLPRGELLASLSDEMLARRAQQGDSEAFDVLVVRHGPALLRFVARTYPERAEYDDI
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHH
VQETFIAAWKGLPSFAFRSQFRTWLYSLASRKTVDAMRRRRRDFDIDEVPEVADAGAGPS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
ERALDGDFLAALSRELSQLPYAARAAWWLREVYDLPLAEIATVLRTTEGSVRGNLQRTRK
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHH
RLAETLKDFRP
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]