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The map label for this gene is coaA

Identifier: 169628327

GI number: 169628327

Start: 1245928

End: 1246860

Strand: Reverse

Name: coaA

Synonym: MAB_1234c

Alternate gene names: 169628327

Gene position: 1246860-1245928 (Counterclockwise)

Preceding gene: 169628334

Following gene: 169628326

Centisome position: 24.61

GC content: 61.63

Gene sequence:

>933_bases
ATGCCGCGGCTGAGCGAGCCGAGCCCCTACGTGGAGTTCGACCGGAAACAGTGGCGCGCGCTGCGCAAATCCACGCCACT
GGTCCTTACCGAAGAAGAGCTGATCGGCCTGCGTGGTCTGGGCGAGCAGATCGACCTGACCGAAGTCGCCGAGGTCTATC
TGCCGCTGGCACGGTTGATCCACCTGCAGGTAGCCGCCCGGCAGCGGCTGTTCGCCGCGACGGCGACCTTCCTCGGCGAC
CAACATCCGGACCGTCTGGTTCCCTTCGTCATTGGCGTGGCGGGCAGCGTCGCCGTCGGCAAGTCCACGACTGCCCGCGT
GCTGCAAGCGCTCCTGGCGCGGTGGGACCATCATCCACGCGTGGACCTCGTCACCACAGACGGATTCTTGTATCCCAACG
CCGAGCTATCGCGACGCAACATCATGCACCGCAAGGGGTTTCCCGAAAGTTACAACAGACGCGGGTTGCTGCGGTTCGTC
ACCGAGGTCAAATCGGGCGCGCGGGAAGTCACCGCGCCGGTGTACTCGCACCTGCTGTACGACATCATCAAAAACGAGAA
ACATGTTGTGCAGCAACCCGATATCCTCATTCTTGAGGGCTTGAACGTGCTGCAGACCGGCCCCACGCTGATGGTCTCGG
ACCTGTTCGATTTCTCGATCTACGTGGACGCACGCATCGAAGACATCGAGCAGTGGTACATCTCCCGCTTCCTCGCGATG
CGGTCCACCTCTTTTGCGAATCCCTCATCGCACTTCCACCATTACGCCAAGCTCTCCGACAAGCAGGCAACCCTGGCCGC
ACAAGAGATTTGGCATTCGATCAACCTGCCGAATCTGCTGGAGAACATATTGCCGACCCGCCCACGCGCGACGCTGGTGC
TCCGCAAGGATGCCGACCACTCGATCAACCGGCTGCGGCTACGCAAGCTGTAA

Upstream 100 bases:

>100_bases
AGGTATTCGGTGACGACACTGTTCTTCGACTCGTCGTTATCGCCCATGTCACACAACCCTAGTGCCGCGTTCACGAATGG
CTCCTGCAAGACTTGCGTTC

Downstream 100 bases:

>100_bases
TCGGTAATCCAGGTAGACCGACTGGTATATTCGCCTGATGATCAACAACGTGGTTGAAACCTGGCACGGCATCATTTCCG
GCGCGAACCCCGAAGCACTC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLIHLQVAARQRLFAATATFLGD
QHPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFV
TEVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAM
RSTSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADHSINRLRLRKL

Sequences:

>Translated_310_residues
MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLIHLQVAARQRLFAATATFLGD
QHPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFV
TEVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAM
RSTSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADHSINRLRLRKL
>Mature_309_residues
PRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLIHLQVAARQRLFAATATFLGDQ
HPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFVT
EVKSGAREVTAPVYSHLLYDIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAMR
STSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADHSINRLRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=309, Percent_Identity=53.0744336569579, Blast_Score=337, Evalue=5e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_MYCA9 (B1MKN0)

Other databases:

- EMBL:   CU458896
- RefSeq:   YP_001701976.1
- ProteinModelPortal:   B1MKN0
- SMR:   B1MKN0
- EnsemblBacteria:   EBMYCT00000004142
- GeneID:   5963758
- GenomeReviews:   CU458896_GR
- KEGG:   mab:MAB_1234c
- GeneTree:   EBGT00050000016369
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   MABS561007:MAB_1234C-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35408; Mature: 35277

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLI
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATATFLGDQHPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFVTEVKSGAREVTAPVYSHLLY
EEEEEECCEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
DIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAM
HHHCCCHHHHCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHHHH
RSTSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADH
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCC
SINRLRLRKL
CHHHHHHCCC
>Mature Secondary Structure 
PRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVAEVYLPLARLI
CCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATATFLGDQHPDRLVPFVIGVAGSVAVGKSTTARVLQALLARWDHHPR
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
VDLVTTDGFLYPNAELSRRNIMHRKGFPESYNRRGLLRFVTEVKSGAREVTAPVYSHLLY
EEEEEECCEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHH
DIIKNEKHVVQQPDILILEGLNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAM
HHHCCCHHHHCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHHHH
RSTSFANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVLRKDADH
HHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEECCCCC
SINRLRLRKL
CHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA