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The map label for this gene is opuCB [H]

Identifier: 169628320

GI number: 169628320

Start: 1239063

End: 1239848

Strand: Direct

Name: opuCB [H]

Synonym: MAB_1227

Alternate gene names: 169628320

Gene position: 1239063-1239848 (Clockwise)

Preceding gene: 169628319

Following gene: 169628321

Centisome position: 24.45

GC content: 67.3

Gene sequence:

>786_bases
ATGACGGCATCAACCATCACCGCGACCGGGGCGGCGCAATCGGCTCCGGCCACCGCCAGGCGGCCCGCACTGGCCGCCAG
GCAGTTGCTACAGCCATCGGCATGCATTGTGGCCGTGATGGTTTCGCTGGCATACGTCAACCTCGCGGACGTATCGGCGT
CGGAGAAGCGCTCGTTGGGGATGTCGAACCTGCTGGTCCTCCTGGGACAGCACATGGCGATCAGCGTCGCCGCGACGGTG
CTCACGTGCGCCGTCGCGATCCCGCTAGGCATCGCATTGACGCGAGGGCCCGTCCGGAGGTACGCGAAGACGATCACCAC
GTTGGTCGGGTTCGGCCAGGCCGCTCCGGCCATCGGACTGATCGCACTCGGGGCGGTGCTGTTCGGCATCGGTGGTATCG
GTGCGGTACTGGCCCTGACCGTCTACGGCGCGCTGCCCATCGTCGCCAATACCGTGATCGGTCTCGACGGTGTCGATACC
CGCCTGGTGGAGGCGGCACGGGGGATGGGGATGTCGGCGCGCTCGACCCTGATCCGGGTGGAATTGCCATTGGCGTTGCG
GGTCATCGTCGCCGGAGTGCGCACCGCGCTGGTGCTCATCGTCGGCACGGCGGCACTGGCATCGTTCACCGGAGCCGGCG
GGCTGGGTCAGCTCATCACCACGGGCATCAAACTTCAGCAGCCGGTGACCCTGGTGGTGGGCGCCATCCTGGTGGCTGCT
CTGGCCTTGTTCATCGACTGGCTGGCCCGCGTCGTCGAGATCATCGCAGCACCAAGGGGGCTGTGA

Upstream 100 bases:

>100_bases
TGACGGGGCGCCGCAACACCTATCAGGGCGTCATCAGGGTCGAGACAATCATGGACGCGATGGCCGAGATGCGGGCCGCG
GCGCAATAGGGGTATCCCAG

Downstream 100 bases:

>100_bases
TGCGAAGGCGTCGACTTGTGGTGCTTGCCTGCTTGGTGATGATGCTGCAGGCAGGCTGCGGTCTCCAGTCCGCGAGCGGC
GCGGTACTCGCCGCCAAGCC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTASTITATGAAQSAPATARRPALAARQLLQPSACIVAVMVSLAYVNLADVSASEKRSLGMSNLLVLLGQHMAISVAATV
LTCAVAIPLGIALTRGPVRRYAKTITTLVGFGQAAPAIGLIALGAVLFGIGGIGAVLALTVYGALPIVANTVIGLDGVDT
RLVEAARGMGMSARSTLIRVELPLALRVIVAGVRTALVLIVGTAALASFTGAGGLGQLITTGIKLQQPVTLVVGAILVAA
LALFIDWLARVVEIIAAPRGL

Sequences:

>Translated_261_residues
MTASTITATGAAQSAPATARRPALAARQLLQPSACIVAVMVSLAYVNLADVSASEKRSLGMSNLLVLLGQHMAISVAATV
LTCAVAIPLGIALTRGPVRRYAKTITTLVGFGQAAPAIGLIALGAVLFGIGGIGAVLALTVYGALPIVANTVIGLDGVDT
RLVEAARGMGMSARSTLIRVELPLALRVIVAGVRTALVLIVGTAALASFTGAGGLGQLITTGIKLQQPVTLVVGAILVAA
LALFIDWLARVVEIIAAPRGL
>Mature_260_residues
TASTITATGAAQSAPATARRPALAARQLLQPSACIVAVMVSLAYVNLADVSASEKRSLGMSNLLVLLGQHMAISVAATVL
TCAVAIPLGIALTRGPVRRYAKTITTLVGFGQAAPAIGLIALGAVLFGIGGIGAVLALTVYGALPIVANTVIGLDGVDTR
LVEAARGMGMSARSTLIRVELPLALRVIVAGVRTALVLIVGTAALASFTGAGGLGQLITTGIKLQQPVTLVVGAILVAAL
ALFIDWLARVVEIIAAPRGL

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=157, Percent_Identity=38.8535031847134, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789033, Length=176, Percent_Identity=35.7954545454545, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788451, Length=196, Percent_Identity=34.1836734693878, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26227; Mature: 26096

Theoretical pI: Translated: 11.56; Mature: 11.56

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASTITATGAAQSAPATARRPALAARQLLQPSACIVAVMVSLAYVNLADVSASEKRSLG
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
MSNLLVLLGQHMAISVAATVLTCAVAIPLGIALTRGPVRRYAKTITTLVGFGQAAPAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IALGAVLFGIGGIGAVLALTVYGALPIVANTVIGLDGVDTRLVEAARGMGMSARSTLIRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEEEE
ELPLALRVIVAGVRTALVLIVGTAALASFTGAGGLGQLITTGIKLQQPVTLVVGAILVAA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
LALFIDWLARVVEIIAAPRGL
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TASTITATGAAQSAPATARRPALAARQLLQPSACIVAVMVSLAYVNLADVSASEKRSLG
CCCCEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
MSNLLVLLGQHMAISVAATVLTCAVAIPLGIALTRGPVRRYAKTITTLVGFGQAAPAIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IALGAVLFGIGGIGAVLALTVYGALPIVANTVIGLDGVDTRLVEAARGMGMSARSTLIRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHEEEEE
ELPLALRVIVAGVRTALVLIVGTAALASFTGAGGLGQLITTGIKLQQPVTLVVGAILVAA
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
LALFIDWLARVVEIIAAPRGL
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]