Definition Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession NC_010397
Length 5,067,172

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The map label for this gene is cyp51 [H]

Identifier: 169628307

GI number: 169628307

Start: 1226021

End: 1227382

Strand: Reverse

Name: cyp51 [H]

Synonym: MAB_1214c

Alternate gene names: 169628307

Gene position: 1227382-1226021 (Counterclockwise)

Preceding gene: 169628308

Following gene: 169628306

Centisome position: 24.22

GC content: 62.48

Gene sequence:

>1362_bases
ATGACCACGCCCACCGTTCCCCGGGTCTCCGGCGGCGAGGACCAATACGGCCACCTCGAAGAGTTCCGCACCGATCCCAT
CGCACTGATGAAGCGCATCCGTGCGGAATGCGGGAACGTCGGCACCTTCCAGCTCGCCGACAAGCAGGTCGTCTTCCTCT
CCGGCGCCGAGGCCAACGAGTTCTTCTTCCGCTCCAGCGACGAAGACCTGGACCAGGCCGAGGCCTATCCGTTCATGACG
CCCATCTTCGGCAAGGGCGTGGTGTTCGACGCCGATCCCGAACGCCGGAAGGAGATGCTGCATAACGCGGCGCTGCGTGG
CGAGCAGATGAAGGGCCATGCCGCAACCATCGAAAATGAAGTCCGGCAGATGATTTCGCGCTGGGGTGAAAGCGGTGAAG
TCGACCTGCTGGACTTCTTCGCCGAGCTGACCATCTACACCTCCTCGGCGTGCCTGATCGGCAAGAAGTTTCGGGACGAA
CTCGACGGCCGGTTCGCTCATCTGTACCACCAGCTGGAGCAGGGGACCGATCCGCTGTGCTACGTGGACCCCTACCTGGA
GATCGAGAGCTTCCGCCAGCGCGACGAGGCGCGAACAGGCTTGGTGGCGCTGGTTCAAGAGATAATCAACGGCCGAGTAC
AACGGTCCGCTGATTCTCCGACGGACAAGAGCCAGCGCGACATGCTCGATGTGCTGATCATGATCAAAGACGAGCACGGC
AATCCGCGCTTCACCGCCGACGAGATCACCGGGATGTTCATCTCGATGATGTTCGCGGGCCACCACACCAGCTCGGGGAC
GGCATCCTGGGTACTCATCGAACTGCTGCGGCACCCGGATATCCAATCTCAGGTGATCGACGAGCTCGACGAGCTGTACG
CCGACGGCAGCGAGGTGAGTTTCCATGCGTTGCGCCAGATCCCGAAGCTGGAGAACGTACTCAAGGAGACGCTGCGGCTG
CACCCGCCCCTGATCATCCTGATGCGTGTCGCCAAGGGCGAATTCGAGGTGGGCGGATTCCCCATTCACGACGGGGACAT
GGTGGCCGCCTCCCCTGCCGTCTCGAATCGGATAGCCGAGGACTTCCCGAACCCGGACGGCTTCGTGCCCGATCGCTACG
AGAAGCCACGCCAGGAAGACATCGTCAACCGCTGGACGTGGATACCGTTCGGCGCGGGCCGGCATCGCTGTGTGGGGGCC
GCCTTCGCCACCATGCAGATCAAGGCGATCTTCTCGGTGCTGTTGCGCGAATACGAGTTTGAGATGGCCCAACCCGCCGA
CTCGTATCACAACGACCACTCGAAGATGGTGGTCCAGCTGGCGCAGCCGGCCAAGGTTCGTTACCGCAAGCGGAGCGCCT
GA

Upstream 100 bases:

>100_bases
GCGCACATATCCCGGAGATGGAAGTGCAGCCGGAAGCACCACTCAAGGATGCACCGGCGGACAAACAGAAGCTTGAGCTC
GGCGAGGAAGGAATGCCCTC

Downstream 100 bases:

>100_bases
TGGCCTACCGGGTCGACGTCGACACCGATCTGTGCCAGGGACACGCCATGTGCGAGCTGGAAGCCCCCGACTACTTCCGT
GTGCCCAAGCGCGGCACCGT

Product: cytochrome P450

Products: NA

Alternate protein names: CYPLI; Cytochrome P450 51; Cytochrome P450-14DM; Cytochrome P450-LIA1; Sterol 14-alpha demethylase [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MTTPTVPRVSGGEDQYGHLEEFRTDPIALMKRIRAECGNVGTFQLADKQVVFLSGAEANEFFFRSSDEDLDQAEAYPFMT
PIFGKGVVFDADPERRKEMLHNAALRGEQMKGHAATIENEVRQMISRWGESGEVDLLDFFAELTIYTSSACLIGKKFRDE
LDGRFAHLYHQLEQGTDPLCYVDPYLEIESFRQRDEARTGLVALVQEIINGRVQRSADSPTDKSQRDMLDVLIMIKDEHG
NPRFTADEITGMFISMMFAGHHTSSGTASWVLIELLRHPDIQSQVIDELDELYADGSEVSFHALRQIPKLENVLKETLRL
HPPLIILMRVAKGEFEVGGFPIHDGDMVAASPAVSNRIAEDFPNPDGFVPDRYEKPRQEDIVNRWTWIPFGAGRHRCVGA
AFATMQIKAIFSVLLREYEFEMAQPADSYHNDHSKMVVQLAQPAKVRYRKRSA

Sequences:

>Translated_453_residues
MTTPTVPRVSGGEDQYGHLEEFRTDPIALMKRIRAECGNVGTFQLADKQVVFLSGAEANEFFFRSSDEDLDQAEAYPFMT
PIFGKGVVFDADPERRKEMLHNAALRGEQMKGHAATIENEVRQMISRWGESGEVDLLDFFAELTIYTSSACLIGKKFRDE
LDGRFAHLYHQLEQGTDPLCYVDPYLEIESFRQRDEARTGLVALVQEIINGRVQRSADSPTDKSQRDMLDVLIMIKDEHG
NPRFTADEITGMFISMMFAGHHTSSGTASWVLIELLRHPDIQSQVIDELDELYADGSEVSFHALRQIPKLENVLKETLRL
HPPLIILMRVAKGEFEVGGFPIHDGDMVAASPAVSNRIAEDFPNPDGFVPDRYEKPRQEDIVNRWTWIPFGAGRHRCVGA
AFATMQIKAIFSVLLREYEFEMAQPADSYHNDHSKMVVQLAQPAKVRYRKRSA
>Mature_452_residues
TTPTVPRVSGGEDQYGHLEEFRTDPIALMKRIRAECGNVGTFQLADKQVVFLSGAEANEFFFRSSDEDLDQAEAYPFMTP
IFGKGVVFDADPERRKEMLHNAALRGEQMKGHAATIENEVRQMISRWGESGEVDLLDFFAELTIYTSSACLIGKKFRDEL
DGRFAHLYHQLEQGTDPLCYVDPYLEIESFRQRDEARTGLVALVQEIINGRVQRSADSPTDKSQRDMLDVLIMIKDEHGN
PRFTADEITGMFISMMFAGHHTSSGTASWVLIELLRHPDIQSQVIDELDELYADGSEVSFHALRQIPKLENVLKETLRLH
PPLIILMRVAKGEFEVGGFPIHDGDMVAASPAVSNRIAEDFPNPDGFVPDRYEKPRQEDIVNRWTWIPFGAGRHRCVGAA
FATMQIKAIFSVLLREYEFEMAQPADSYHNDHSKMVVQLAQPAKVRYRKRSA

Specific function: Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene- 3-beta-o

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503243, Length=446, Percent_Identity=33.8565022421525, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI225903399, Length=418, Percent_Identity=34.2105263157895, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI187960086, Length=238, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI13435386, Length=223, Percent_Identity=28.2511210762332, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI16933528, Length=353, Percent_Identity=27.7620396600567, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI16933530, Length=353, Percent_Identity=27.7620396600567, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI262290932, Length=224, Percent_Identity=29.0178571428571, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4503231, Length=219, Percent_Identity=29.6803652968037, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI16933533, Length=223, Percent_Identity=27.3542600896861, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI13435391, Length=375, Percent_Identity=25.6, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI119220562, Length=374, Percent_Identity=25.668449197861, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI193083180, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI193083178, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI150036266, Length=369, Percent_Identity=24.390243902439, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI30023836, Length=377, Percent_Identity=23.6074270557029, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI12383060, Length=223, Percent_Identity=26.457399103139, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI167466231, Length=208, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI5729796, Length=175, Percent_Identity=31.4285714285714, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI9845285, Length=400, Percent_Identity=24, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI158937242, Length=370, Percent_Identity=22.4324324324324, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI6005737, Length=219, Percent_Identity=28.7671232876712, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI62952506, Length=428, Percent_Identity=21.9626168224299, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4503213, Length=180, Percent_Identity=31.1111111111111, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI32313587, Length=451, Percent_Identity=21.0643015521064, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI158138530, Length=374, Percent_Identity=22.192513368984, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI62952502, Length=454, Percent_Identity=22.9074889867841, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI55770850, Length=229, Percent_Identity=21.3973799126638, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI261278372, Length=180, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI261278370, Length=180, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI195972896, Length=180, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI195972898, Length=180, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI29837648, Length=368, Percent_Identity=22.0108695652174, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI166362724, Length=490, Percent_Identity=23.6734693877551, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4503211, Length=184, Percent_Identity=27.7173913043478, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI13699809, Length=421, Percent_Identity=24.4655581947743, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI189339233, Length=419, Percent_Identity=23.6276849642005, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4503195, Length=289, Percent_Identity=22.4913494809689, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI153218662, Length=379, Percent_Identity=21.8997361477573, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI153218660, Length=383, Percent_Identity=21.9321148825065, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI13904858, Length=349, Percent_Identity=21.2034383954155, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13904860, Length=349, Percent_Identity=21.2034383954155, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI18491008, Length=201, Percent_Identity=25.8706467661692, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI15147330, Length=413, Percent_Identity=23.4866828087167, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI310125130, Length=257, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI190570174, Length=257, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI310125128, Length=257, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI14550409, Length=257, Percent_Identity=23.3463035019455, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI34098959, Length=256, Percent_Identity=23.4375, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI64368472, Length=408, Percent_Identity=24.2647058823529, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI16933535, Length=174, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4758104, Length=447, Percent_Identity=21.0290827740492, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI10834998, Length=235, Percent_Identity=24.2553191489362, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI40805836, Length=457, Percent_Identity=23.1947483588621, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI4503199, Length=446, Percent_Identity=19.7309417040359, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7949031, Length=426, Percent_Identity=22.5352112676056, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI15147328, Length=232, Percent_Identity=22.4137931034483, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI166295200, Length=269, Percent_Identity=24.1635687732342, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI68509921, Length=219, Percent_Identity=25.1141552511416, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72001056, Length=387, Percent_Identity=25.5813953488372, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI212646200, Length=417, Percent_Identity=23.9808153477218, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17564386, Length=370, Percent_Identity=25.4054054054054, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193206712, Length=416, Percent_Identity=24.0384615384615, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560320, Length=417, Percent_Identity=23.7410071942446, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71990269, Length=416, Percent_Identity=24.0384615384615, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985409, Length=200, Percent_Identity=32, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982956, Length=252, Percent_Identity=25, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI115532670, Length=227, Percent_Identity=25.9911894273128, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982977, Length=252, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI72001484, Length=422, Percent_Identity=23.696682464455, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115534628, Length=262, Percent_Identity=24.4274809160305, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536183, Length=366, Percent_Identity=24.3169398907104, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17536187, Length=397, Percent_Identity=22.1662468513854, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998720, Length=197, Percent_Identity=27.9187817258883, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25146185, Length=438, Percent_Identity=22.3744292237443, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17536179, Length=192, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17552522, Length=227, Percent_Identity=25.5506607929515, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17553064, Length=372, Percent_Identity=23.6559139784946, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17536177, Length=378, Percent_Identity=23.015873015873, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551418, Length=235, Percent_Identity=25.531914893617, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551420, Length=235, Percent_Identity=25.531914893617, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540354, Length=227, Percent_Identity=25.1101321585903, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564244, Length=326, Percent_Identity=23.9263803680982, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17536191, Length=373, Percent_Identity=22.2520107238606, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562424, Length=298, Percent_Identity=24.1610738255034, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17557264, Length=212, Percent_Identity=27.8301886792453, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17553062, Length=184, Percent_Identity=28.804347826087, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25147224, Length=197, Percent_Identity=26.9035532994924, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17531287, Length=181, Percent_Identity=24.8618784530387, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536175, Length=375, Percent_Identity=23.2, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536185, Length=360, Percent_Identity=21.9444444444444, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565220, Length=442, Percent_Identity=23.3031674208145, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564242, Length=321, Percent_Identity=25.2336448598131, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560844, Length=177, Percent_Identity=25.4237288135593, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17569243, Length=196, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560938, Length=177, Percent_Identity=23.728813559322, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557254, Length=311, Percent_Identity=22.8295819935691, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560836, Length=177, Percent_Identity=24.2937853107345, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568777, Length=221, Percent_Identity=25.7918552036199, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206291, Length=235, Percent_Identity=22.1276595744681, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193207072, Length=289, Percent_Identity=22.1453287197232, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993251, Length=356, Percent_Identity=20.7865168539326, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17558662, Length=182, Percent_Identity=23.6263736263736, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17568779, Length=188, Percent_Identity=26.063829787234, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17568775, Length=184, Percent_Identity=27.1739130434783, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17557258, Length=200, Percent_Identity=25.5, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558634, Length=184, Percent_Identity=24.4565217391304, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558554, Length=230, Percent_Identity=26.9565217391304, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72001009, Length=189, Percent_Identity=25.3968253968254, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558708, Length=297, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321795, Length=459, Percent_Identity=28.7581699346405, Blast_Score=202, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6323657, Length=173, Percent_Identity=26.0115606936416, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24660171, Length=443, Percent_Identity=25.9593679458239, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17864130, Length=229, Percent_Identity=29.6943231441048, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639287, Length=199, Percent_Identity=28.1407035175879, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639289, Length=199, Percent_Identity=28.1407035175879, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641309, Length=191, Percent_Identity=30.3664921465969, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24656064, Length=200, Percent_Identity=32.5, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI221330299, Length=218, Percent_Identity=27.0642201834862, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17933518, Length=200, Percent_Identity=32, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920740, Length=417, Percent_Identity=22.3021582733813, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18860031, Length=189, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281364464, Length=376, Percent_Identity=22.6063829787234, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21358271, Length=370, Percent_Identity=24.8648648648649, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17933498, Length=428, Percent_Identity=22.8971962616822, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920744, Length=399, Percent_Identity=23.0576441102757, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642101, Length=217, Percent_Identity=29.0322580645161, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355669, Length=206, Percent_Identity=29.126213592233, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21355401, Length=238, Percent_Identity=31.0924369747899, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330273, Length=243, Percent_Identity=28.3950617283951, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24582534, Length=202, Percent_Identity=30.6930693069307, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921820, Length=395, Percent_Identity=24.0506329113924, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28571357, Length=439, Percent_Identity=23.4624145785877, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19921824, Length=203, Percent_Identity=26.1083743842365, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24653737, Length=231, Percent_Identity=29.4372294372294, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI21357631, Length=348, Percent_Identity=25.8620689655172, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357003, Length=341, Percent_Identity=24.0469208211144, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI221330275, Length=228, Percent_Identity=27.6315789473684, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24653745, Length=204, Percent_Identity=28.921568627451, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24641483, Length=392, Percent_Identity=23.2142857142857, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45553345, Length=185, Percent_Identity=28.6486486486486, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653747, Length=208, Percent_Identity=29.3269230769231, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357069, Length=185, Percent_Identity=28.6486486486486, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550374, Length=198, Percent_Identity=31.3131313131313, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24652454, Length=206, Percent_Identity=27.1844660194175, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI17737439, Length=236, Percent_Identity=26.6949152542373, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI45552561, Length=207, Percent_Identity=26.5700483091787, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573913, Length=207, Percent_Identity=26.5700483091787, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653739, Length=230, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24652913, Length=212, Percent_Identity=27.3584905660377, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17647303, Length=217, Percent_Identity=25.8064516129032, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24943083, Length=179, Percent_Identity=27.3743016759777, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21358627, Length=391, Percent_Identity=21.4833759590793, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45552577, Length=179, Percent_Identity=27.3743016759777, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24652915, Length=217, Percent_Identity=26.2672811059908, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19922290, Length=246, Percent_Identity=26.0162601626016, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24653734, Length=253, Percent_Identity=24.5059288537549, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24652917, Length=176, Percent_Identity=29.5454545454545, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21358207, Length=188, Percent_Identity=24.468085106383, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI19921686, Length=339, Percent_Identity=22.4188790560472, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24657167, Length=221, Percent_Identity=24.8868778280543, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646219, Length=284, Percent_Identity=25.3521126760563, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647305, Length=197, Percent_Identity=27.9187817258883, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24586583, Length=215, Percent_Identity=25.1162790697674, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18079270, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647309, Length=182, Percent_Identity=25.2747252747253, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647307, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864382, Length=195, Percent_Identity=26.1538461538462, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648130, Length=190, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19921490, Length=165, Percent_Identity=28.4848484848485, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921314, Length=217, Percent_Identity=24.4239631336406, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864466, Length=310, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358007, Length=179, Percent_Identity=25.1396648044693, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161078232, Length=327, Percent_Identity=22.6299694189602, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653207, Length=239, Percent_Identity=25.1046025104602, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356685, Length=183, Percent_Identity=25.6830601092896, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19921894, Length=215, Percent_Identity=26.9767441860465, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355711, Length=249, Percent_Identity=23.6947791164659, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550107, Length=226, Percent_Identity=23.4513274336283, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45553093, Length=253, Percent_Identity=21.3438735177866, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR017972
- InterPro:   IPR002403 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: =1.14.13.70 [H]

Molecular weight: Translated: 51331; Mature: 51200

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTTPTVPRVSGGEDQYGHLEEFRTDPIALMKRIRAECGNVGTFQLADKQVVFLSGAEANE
CCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCH
FFFRSSDEDLDQAEAYPFMTPIFGKGVVFDADPERRKEMLHNAALRGEQMKGHAATIENE
HEECCCCCCHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VRQMISRWGESGEVDLLDFFAELTIYTSSACLIGKKFRDELDGRFAHLYHQLEQGTDPLC
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YVDPYLEIESFRQRDEARTGLVALVQEIINGRVQRSADSPTDKSQRDMLDVLIMIKDEHG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHEEEEEECCCC
NPRFTADEITGMFISMMFAGHHTSSGTASWVLIELLRHPDIQSQVIDELDELYADGSEVS
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
FHALRQIPKLENVLKETLRLHPPLIILMRVAKGEFEVGGFPIHDGDMVAASPAVSNRIAE
HHHHHHCHHHHHHHHHHHHHCCCHHEEEHHHCCCEECCCEECCCCCCEECCCHHHHHHHH
DFPNPDGFVPDRYEKPRQEDIVNRWTWIPFGAGRHRCVGAAFATMQIKAIFSVLLREYEF
HCCCCCCCCCCCCCCCCHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQPADSYHNDHSKMVVQLAQPAKVRYRKRSA
HHCCCCHHHCCCHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TTPTVPRVSGGEDQYGHLEEFRTDPIALMKRIRAECGNVGTFQLADKQVVFLSGAEANE
CCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEECCCCCH
FFFRSSDEDLDQAEAYPFMTPIFGKGVVFDADPERRKEMLHNAALRGEQMKGHAATIENE
HEECCCCCCHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VRQMISRWGESGEVDLLDFFAELTIYTSSACLIGKKFRDELDGRFAHLYHQLEQGTDPLC
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YVDPYLEIESFRQRDEARTGLVALVQEIINGRVQRSADSPTDKSQRDMLDVLIMIKDEHG
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHEEEEEECCCC
NPRFTADEITGMFISMMFAGHHTSSGTASWVLIELLRHPDIQSQVIDELDELYADGSEVS
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHH
FHALRQIPKLENVLKETLRLHPPLIILMRVAKGEFEVGGFPIHDGDMVAASPAVSNRIAE
HHHHHHCHHHHHHHHHHHHHCCCHHEEEHHHCCCEECCCEECCCCCCEECCCHHHHHHHH
DFPNPDGFVPDRYEKPRQEDIVNRWTWIPFGAGRHRCVGAAFATMQIKAIFSVLLREYEF
HCCCCCCCCCCCCCCCCHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQPADSYHNDHSKMVVQLAQPAKVRYRKRSA
HHCCCCHHHCCCHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]