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The map label for this gene is pks16 [H]

Identifier: 169628233

GI number: 169628233

Start: 1155607

End: 1157256

Strand: Direct

Name: pks16 [H]

Synonym: MAB_1140

Alternate gene names: 169628233

Gene position: 1155607-1157256 (Clockwise)

Preceding gene: 169628232

Following gene: 169628239

Centisome position: 22.81

GC content: 65.7

Gene sequence:

>1650_bases
GTGAGCAGGTTTACCGACGAGCTGTACGCCAACGCGCTGTCAAGCAGCAAGGGCATGGTCACCGGCGAACCCGATACTCC
GGTCCGGCATACCTGGAAGCAGGTCCACGAGCGCGCCAAGCAAGTTGCGGGTGGACTCGCTGGAGCTGGGCTTGGCCCTG
ACGATGCCATCGGCATGTTGGTCGGCATGCCCGTGGAGATCGCTCCGGCGATCCAGGCCGTGTGGATGCGCGGTGCCTCG
CTGACAATGCTGCACCAGCCGACCCCGCGTACCGACCTCGCCGTATGGGCCGAGGACACCCTCAAGGTCGTCGACATGAT
CGGCGCCAAGGCCGTCATCGTGTCCGCTCCGTTCGACGCCGCCGCTCCGGTTCTGGAGGAGAAGGGCGTCATCGTCGTGC
ACATCAAGGATCTGTGGGACGCCGACCCGATCGAACCCCTCGAGGCCGATGAGGACTCCGTCGCCCTCATGCAGCTGACG
TCCGGCTCGACCGGATCTCCCAAGGCCGTCAAAATCACCCACCGCAACCTGTACGCCAACGCGCACGGCATGTACGTCGC
CTCCAAGTACAAGCCCGAAATCGACGTCATGGTCAGCTGGCTGCCGCTATTCCACGATATGGGCATGGTCGGCTTCCTGA
CGGTGCCCATGTTCTTCGGCGCCGAGCTCGTGAAGATCACCCCGATGGACTTCATGCGCGATGTTTTGTTGTGGGGCAGG
CTGATCGACAAGTACAAGGGCACCATGACGGCCGCTCCGAACTTCGCGTACTCGTTGTTCGCCAAGCGGCTGCGCAACCA
GGCCAAGCCGGGCGACTTCGACCTCTCGACGCTGCGGTTCGTGCTTTCCGGTGCCGAGCCGGTGGACCCCGCCGTGGTCG
AGGACCTATGTGATGCTGGAAAGCCGTTCGGCTTCAAGCCTTCTGCGATGGTGCCCGCCTACGGCATGGCGGAAACCGCG
CTGGCCGTGTCCTTCTCGGAGGTCGAGGCCTCCGGTCTGGTTGTCGACGAGGTCGACGCCGATCTGCTGGCCGCCCTGCG
GCGAGCCGTTCCCGCCACCCGTGGCAACCTGCGCCATTTGGCCACGCTGGGCCCCCTGCTGCCCGGTATCGAGGCACGGG
TTGTCGACGAGGACCTGAACGTGCTGCCTGCGCGCGGCGTCGGTGTCATCGAACTGCGTGGCGAGTCGGTGACTCCCGGT
TATGTGACCATGGGCGGATTTTTGGCCGCGCAGGACGAAAACGGTTGGTACAACACCGGCGACCTCGGCTACCTGACCGA
GAAGGGCCACGTTGTGGTGTGCGGTCGCGTCAAGGACGTCATCATCATGGCGGGCCGCAACATCTACCCGACCGATATCG
AGCGTGCCGCAGGCCGCGTCGACGGGGTGCGCCCCGGCTGCGCCGTCGCCGTGCGGTTGGAGGCCGGTGTGGACCCCAAG
AACCAGCGCGAGACCTTCGCGGTTGTGGTGGAGTCCAACGCCTTCGAGAATCCGGACGAGGTGCGGCGGATCGAGCAGCA
GGTTGCCCACGAGGTGGTCGCCGAGGTAGACGTACGGCCCCGCAACGTGGTGGTGCTCGGCCCGGGCAGCATCCCCAAGA
CCCCGTCGGGCAAGCTGCGCCGCTCGACGTCGGTGGCGCTCGTCATCTAG

Upstream 100 bases:

>100_bases
CTACAGGCTCCGCGCGCGCCTACCGCACGTCGCGGCCTAGGTGGCGGACCATCCGATAAGGAAGCGTGACTCGCCCAGCA
GGCCTAGGCCAGGAGGAACT

Downstream 100 bases:

>100_bases
GGCCTACCGCAAGGCGTCGAACGACCAACGCCGAACGTAACGCCACGCACTGAATCGACGCAGATCGTATGTGTGCGGTT
ACATTCGCGCAGCGACATCA

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MSRFTDELYANALSSSKGMVTGEPDTPVRHTWKQVHERAKQVAGGLAGAGLGPDDAIGMLVGMPVEIAPAIQAVWMRGAS
LTMLHQPTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDAAAPVLEEKGVIVVHIKDLWDADPIEPLEADEDSVALMQLT
SGSTGSPKAVKITHRNLYANAHGMYVASKYKPEIDVMVSWLPLFHDMGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGR
LIDKYKGTMTAAPNFAYSLFAKRLRNQAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAGKPFGFKPSAMVPAYGMAETA
LAVSFSEVEASGLVVDEVDADLLAALRRAVPATRGNLRHLATLGPLLPGIEARVVDEDLNVLPARGVGVIELRGESVTPG
YVTMGGFLAAQDENGWYNTGDLGYLTEKGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPK
NQRETFAVVVESNAFENPDEVRRIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLRRSTSVALVI

Sequences:

>Translated_549_residues
MSRFTDELYANALSSSKGMVTGEPDTPVRHTWKQVHERAKQVAGGLAGAGLGPDDAIGMLVGMPVEIAPAIQAVWMRGAS
LTMLHQPTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDAAAPVLEEKGVIVVHIKDLWDADPIEPLEADEDSVALMQLT
SGSTGSPKAVKITHRNLYANAHGMYVASKYKPEIDVMVSWLPLFHDMGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGR
LIDKYKGTMTAAPNFAYSLFAKRLRNQAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAGKPFGFKPSAMVPAYGMAETA
LAVSFSEVEASGLVVDEVDADLLAALRRAVPATRGNLRHLATLGPLLPGIEARVVDEDLNVLPARGVGVIELRGESVTPG
YVTMGGFLAAQDENGWYNTGDLGYLTEKGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPK
NQRETFAVVVESNAFENPDEVRRIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLRRSTSVALVI
>Mature_548_residues
SRFTDELYANALSSSKGMVTGEPDTPVRHTWKQVHERAKQVAGGLAGAGLGPDDAIGMLVGMPVEIAPAIQAVWMRGASL
TMLHQPTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDAAAPVLEEKGVIVVHIKDLWDADPIEPLEADEDSVALMQLTS
GSTGSPKAVKITHRNLYANAHGMYVASKYKPEIDVMVSWLPLFHDMGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGRL
IDKYKGTMTAAPNFAYSLFAKRLRNQAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAGKPFGFKPSAMVPAYGMAETAL
AVSFSEVEASGLVVDEVDADLLAALRRAVPATRGNLRHLATLGPLLPGIEARVVDEDLNVLPARGVGVIELRGESVTPGY
VTMGGFLAAQDENGWYNTGDLGYLTEKGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPKN
QRETFAVVVESNAFENPDEVRRIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLRRSTSVALVI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=311, Percent_Identity=26.3665594855305, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI187761345, Length=475, Percent_Identity=22.3157894736842, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI187761343, Length=475, Percent_Identity=22.3157894736842, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI145693145, Length=395, Percent_Identity=28.6075949367089, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788107, Length=325, Percent_Identity=27.6923076923077, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789201, Length=313, Percent_Identity=28.1150159744409, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17558820, Length=400, Percent_Identity=24, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17560308, Length=396, Percent_Identity=25.5050505050505, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563687, Length=389, Percent_Identity=23.1362467866324, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559526, Length=328, Percent_Identity=22.8658536585366, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531443, Length=410, Percent_Identity=22.1951219512195, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24581924, Length=416, Percent_Identity=25, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI20130357, Length=424, Percent_Identity=24.5283018867925, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356947, Length=497, Percent_Identity=23.3400402414487, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 58995; Mature: 58863

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFTDELYANALSSSKGMVTGEPDTPVRHTWKQVHERAKQVAGGLAGAGLGPDDAIGML
CCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
VGMPVEIAPAIQAVWMRGASLTMLHQPTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDA
HCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCEEEEECCCCH
AAPVLEEKGVIVVHIKDLWDADPIEPLEADEDSVALMQLTSGSTGSPKAVKITHRNLYAN
HCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECEEEEC
AHGMYVASKYKPEIDVMVSWLPLFHDMGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGR
CCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
LIDKYKGTMTAAPNFAYSLFAKRLRNQAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAG
HHHHHCCCEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCC
KPFGFKPSAMVPAYGMAETALAVSFSEVEASGLVVDEVDADLLAALRRAVPATRGNLRHL
CCCCCCCCCCCCCCCCHHHHHEEEHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHH
ATLGPLLPGIEARVVDEDLNVLPARGVGVIELRGESVTPGYVTMGGFLAAQDENGWYNTG
HHHHHHCCCCEEEEECCCCCEECCCCEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCC
DLGYLTEKGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPK
CCCEEECCCCEEEEECCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCC
NQRETFAVVVESNAFENPDEVRRIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLR
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
RSTSVALVI
CCCCEEEEC
>Mature Secondary Structure 
SRFTDELYANALSSSKGMVTGEPDTPVRHTWKQVHERAKQVAGGLAGAGLGPDDAIGML
CCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
VGMPVEIAPAIQAVWMRGASLTMLHQPTPRTDLAVWAEDTLKVVDMIGAKAVIVSAPFDA
HCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCEEEEECCCCH
AAPVLEEKGVIVVHIKDLWDADPIEPLEADEDSVALMQLTSGSTGSPKAVKITHRNLYAN
HCCHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEEECEEEEC
AHGMYVASKYKPEIDVMVSWLPLFHDMGMVGFLTVPMFFGAELVKITPMDFMRDVLLWGR
CCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHH
LIDKYKGTMTAAPNFAYSLFAKRLRNQAKPGDFDLSTLRFVLSGAEPVDPAVVEDLCDAG
HHHHHCCCEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCC
KPFGFKPSAMVPAYGMAETALAVSFSEVEASGLVVDEVDADLLAALRRAVPATRGNLRHL
CCCCCCCCCCCCCCCCHHHHHEEEHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCHHHH
ATLGPLLPGIEARVVDEDLNVLPARGVGVIELRGESVTPGYVTMGGFLAAQDENGWYNTG
HHHHHHCCCCEEEEECCCCCEECCCCEEEEEECCCCCCCCEEEECCEEEEECCCCCCCCC
DLGYLTEKGHVVVCGRVKDVIIMAGRNIYPTDIERAAGRVDGVRPGCAVAVRLEAGVDPK
CCCEEECCCCEEEEECCCEEEEEECCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCC
NQRETFAVVVESNAFENPDEVRRIEQQVAHEVVAEVDVRPRNVVVLGPGSIPKTPSGKLR
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCC
RSTSVALVI
CCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]