Click here to switch to the map view.

The map label for this gene is mntH [H]

Identifier: 169628126

GI number: 169628126

Start: 1040447

End: 1041676

Strand: Reverse

Name: mntH [H]

Synonym: MAB_1031c

Alternate gene names: 169628126

Gene position: 1041676-1040447 (Counterclockwise)

Preceding gene: 169628127

Following gene: 169628124

Centisome position: 20.56

GC content: 65.85

Gene sequence:

>1230_bases
GTGCTGGAGCGACAGAAGCAGGCACGGCCATTGCGCGGGCTCTCCCTACTGGGCCCCGCCTTCGTCGCAGCCATTGCCTA
CGTCGACCCCGGAAACGTCGCCTCGAATGTCAGCGCCGGGGCCAAGTACGGCTTCTTGCTGGTCTGGGTGATCGTCACCG
CCAACGTGATGGCCGGCCTGGTGCAATACCTCTCGGCGAAGCTGGGCCTCGTCACCGGACAGTCGCTACCGGAGGCGATC
GGCGATCGCATGGCACGGCCCACTCGGCTGACATTTTGGCTGCAGGCCGAATTAGTCGCCATGGCAACGGATTTGGCTGA
AGTAGTGGGCGGCGCCATCGCGCTACATCTATTGTTCGGCCTGCCGCTACTCCTTGGCGGTGTCATCACCGGAATAGTCT
CGATGGCACTGCTGACCGTGCAAGACCGCCGCGGCCAGCGCTCCTTCGAATACGTGATATCCGCCCTACTGGCCATCATC
GCCATCGGTTTCCTGGCCAGTGTCGTGGTGGAGCCGCCGCCGTTGCCCGAAGCCGCCGCCGGGCTCATCCCGCACTTTCA
GGGCACCGAGAGCCTGCTGCTGGCAACGGCGATGCTGGGCGCGACGGTGATGCCACACGCGGTGTATCTGCACTCCGGCC
TGACCCGGGACCGACACGGAAGACCCGCGGAGGGCGAGCCGCGACGACGCCTGCTGCGCATCACGCGCTGGGACGTATGC
CTGGCGATGGTCTTCGCGGGCGCCGTCAACATGGCCATGCTGCTGGCGGCCGCCACCAATCTGCGGGGACGCGACGGCGT
CGACACCATCGAGGGTGCGCACGCCGCGGTCCGCGACAGCCTGGGACCCACCGTGGCGCTGCTGTTCGCGATCGGCCTGC
TGGCATCCGGGCTCGCATCGTCATCGGTCGGCGCCTATGCCGGCGCGATGATCATGCAAGGACTACTGCGCCGATCCATC
CCCATCGTCGCGCGACGGCTGATCACCCTGCTGCCCGCGCTGGCGATTCTCGCGGCGGGCATCGACCCCACCCGCGCACT
GGTGATATCGCAGGTGGTGTTGTCCTTCGGCATTCCCTTCGCCCTCATACCGCTGATCCGATTGACCGGCGACCGCCGGC
TGATGGGCAGCGATGCCAATCATCGGGTGACCACGCTGCTGGGCTGGATTATTGCCGCGCTAATTTCGGCGCTCAACGTT
GTCCTGATTTTCCTTACCCTTGCGAACTAG

Upstream 100 bases:

>100_bases
CTAGCCAACGGGCGCCCCCGCCCCGGCGCGGACTCGCATGACCTCAAAGTTTCGGCTACTCTAACTTTTCTATTCGGAGT
GCTTGAAACAGGAGGTAGGT

Downstream 100 bases:

>100_bases
TTTCGTCTGGGAGTAGGCTGTGAATCATGAAACGAATCCTGCCCTCAGCCAGCCGATTTGGGCTGGCAATTGGAGTCGTT
GCTAGTGGTTTGTTCTTGGG

Product: manganese transport protein MntH

Products: NA

Alternate protein names: BRAMP [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLERQKQARPLRGLSLLGPAFVAAIAYVDPGNVASNVSAGAKYGFLLVWVIVTANVMAGLVQYLSAKLGLVTGQSLPEAI
GDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFGLPLLLGGVITGIVSMALLTVQDRRGQRSFEYVISALLAII
AIGFLASVVVEPPPLPEAAAGLIPHFQGTESLLLATAMLGATVMPHAVYLHSGLTRDRHGRPAEGEPRRRLLRITRWDVC
LAMVFAGAVNMAMLLAAATNLRGRDGVDTIEGAHAAVRDSLGPTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSI
PIVARRLITLLPALAILAAGIDPTRALVISQVVLSFGIPFALIPLIRLTGDRRLMGSDANHRVTTLLGWIIAALISALNV
VLIFLTLAN

Sequences:

>Translated_409_residues
MLERQKQARPLRGLSLLGPAFVAAIAYVDPGNVASNVSAGAKYGFLLVWVIVTANVMAGLVQYLSAKLGLVTGQSLPEAI
GDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFGLPLLLGGVITGIVSMALLTVQDRRGQRSFEYVISALLAII
AIGFLASVVVEPPPLPEAAAGLIPHFQGTESLLLATAMLGATVMPHAVYLHSGLTRDRHGRPAEGEPRRRLLRITRWDVC
LAMVFAGAVNMAMLLAAATNLRGRDGVDTIEGAHAAVRDSLGPTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSI
PIVARRLITLLPALAILAAGIDPTRALVISQVVLSFGIPFALIPLIRLTGDRRLMGSDANHRVTTLLGWIIAALISALNV
VLIFLTLAN
>Mature_409_residues
MLERQKQARPLRGLSLLGPAFVAAIAYVDPGNVASNVSAGAKYGFLLVWVIVTANVMAGLVQYLSAKLGLVTGQSLPEAI
GDRMARPTRLTFWLQAELVAMATDLAEVVGGAIALHLLFGLPLLLGGVITGIVSMALLTVQDRRGQRSFEYVISALLAII
AIGFLASVVVEPPPLPEAAAGLIPHFQGTESLLLATAMLGATVMPHAVYLHSGLTRDRHGRPAEGEPRRRLLRITRWDVC
LAMVFAGAVNMAMLLAAATNLRGRDGVDTIEGAHAAVRDSLGPTVALLFAIGLLASGLASSSVGAYAGAMIMQGLLRRSI
PIVARRLITLLPALAILAAGIDPTRALVISQVVLSFGIPFALIPLIRLTGDRRLMGSDANHRVTTLLGWIIAALISALNV
VLIFLTLAN

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=422, Percent_Identity=31.5165876777251, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI295293171, Length=439, Percent_Identity=29.1571753986333, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI295293169, Length=439, Percent_Identity=29.1571753986333, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI295293178, Length=439, Percent_Identity=29.1571753986333, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI295293167, Length=444, Percent_Identity=29.5045045045045, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI295293175, Length=439, Percent_Identity=29.1571753986333, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI295293173, Length=439, Percent_Identity=29.1571753986333, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI10835169, Length=439, Percent_Identity=29.1571753986333, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1788736, Length=401, Percent_Identity=45.1371571072319, Blast_Score=337, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17569473, Length=396, Percent_Identity=31.0606060606061, Blast_Score=178, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI193210616, Length=437, Percent_Identity=27.4599542334096, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71999499, Length=432, Percent_Identity=28.4722222222222, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI71993856, Length=204, Percent_Identity=34.8039215686275, Blast_Score=131, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6323062, Length=392, Percent_Identity=32.1428571428571, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6324450, Length=421, Percent_Identity=28.978622327791, Blast_Score=153, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6321841, Length=402, Percent_Identity=31.0945273631841, Blast_Score=143, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24648607, Length=434, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI281362176, Length=434, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24648609, Length=434, Percent_Identity=28.5714285714286, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI45553443, Length=405, Percent_Identity=30.1234567901235, Blast_Score=167, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025
- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF03358 FMN_red; PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 43017; Mature: 43017

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972; 9632246 [H]