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The map label for this gene is arsC [H]

Identifier: 169628088

GI number: 169628088

Start: 999760

End: 1000101

Strand: Direct

Name: arsC [H]

Synonym: MAB_0992

Alternate gene names: 169628088

Gene position: 999760-1000101 (Clockwise)

Preceding gene: 169628086

Following gene: 169628090

Centisome position: 19.73

GC content: 63.45

Gene sequence:

>342_bases
GTGGACGCGACCATTTACCACAATCCCAGATGCACGAAGTCCCGTCAGGCTCTGGCGCGGTTGGAGGAGGCGGGGATTAA
CGTCACCGTCGTCAAGTACCTCGACGATGTGCCCACCACGACGCAGCTGAAAAAGCTGATCGCGGACGCGGGGCTGACGG
TGCGGGAGGCAGTGCGCACCGGGGAGACCGAGTACAAGGAATTAGGCCTTGCTGACGCATCCGATGACGCCTTGCTCGAC
GCAATGGTTGCGCACCCGCGGTTAATTCAGCGTCCGTTCGTGGTGACCGCCAAGGGGACCCGGATGGCCCGGCCCACGGA
GGCGGTCGACGAGATCCTCTAG

Upstream 100 bases:

>100_bases
CTAACGACCCCCACCGACAGCCGCCAGAGCAATGTGACGGCAGAAACTGTTGTGGCAGAAGAAATTTATGTCGCGGCTTG
CGTACCTGTAGGTTGAACGC

Downstream 100 bases:

>100_bases
CCCGGTCCGGTCAGGACGGCTTGCGCGACCTTGCGGAACGCTGCGACGAGTCGTCCCCGGTCGTCGGCGCGGGTGGCTAT
GGCCACGTGGCTAGGTTCCA

Product: arsenate reductase (ArsC)

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MDATIYHNPRCTKSRQALARLEEAGINVTVVKYLDDVPTTTQLKKLIADAGLTVREAVRTGETEYKELGLADASDDALLD
AMVAHPRLIQRPFVVTAKGTRMARPTEAVDEIL

Sequences:

>Translated_113_residues
MDATIYHNPRCTKSRQALARLEEAGINVTVVKYLDDVPTTTQLKKLIADAGLTVREAVRTGETEYKELGLADASDDALLD
AMVAHPRLIQRPFVVTAKGTRMARPTEAVDEIL
>Mature_113_residues
MDATIYHNPRCTKSRQALARLEEAGINVTVVKYLDDVPTTTQLKKLIADAGLTVREAVRTGETEYKELGLADASDDALLD
AMVAHPRLIQRPFVVTAKGTRMARPTEAVDEIL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=114, Percent_Identity=49.1228070175439, Blast_Score=110, Evalue=3e-26,
Organism=Escherichia coli, GI1788841, Length=112, Percent_Identity=45.5357142857143, Blast_Score=93, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 12421; Mature: 12421

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATIYHNPRCTKSRQALARLEEAGINVTVVKYLDDVPTTTQLKKLIADAGLTVREAVRT
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHC
GETEYKELGLADASDDALLDAMVAHPRLIQRPFVVTAKGTRMARPTEAVDEIL
CCHHHHHCCCCCCCCHHHHHHHHHCHHHHCCCEEEEECCCCCCCCHHHHHHCC
>Mature Secondary Structure
MDATIYHNPRCTKSRQALARLEEAGINVTVVKYLDDVPTTTQLKKLIADAGLTVREAVRT
CCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHC
GETEYKELGLADASDDALLDAMVAHPRLIQRPFVVTAKGTRMARPTEAVDEIL
CCHHHHHCCCCCCCCHHHHHHHHHCHHHHCCCEEEEECCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9006011 [H]