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The map label for this gene is fklB [C]

Identifier: 169628051

GI number: 169628051

Start: 962334

End: 962693

Strand: Direct

Name: fklB [C]

Synonym: MAB_0954

Alternate gene names: 169628051

Gene position: 962334-962693 (Clockwise)

Preceding gene: 169628050

Following gene: 169628054

Centisome position: 18.99

GC content: 65.28

Gene sequence:

>360_bases
ATGACGAAACCCGAGATCGACTTTCAGCCAGGTCCGCCGCCCACCGAACTGGTCATCAAGGACATCACCGTCGGTGACGG
TGCGGAGGCCACCCCCGGATCGGTCGTCGACGTGCATTACGTCGGTGTGGAGTTCGAGAGTGGCGAGGAGTTCGACAGCT
CCTGGAACCGCGGCGAGTCCATCGAATTCCCGTTGAGCGCGCTGATCAAGGGCTGGCAGGACGGCATTCCCGGCATGAAG
GTGGGCGGACGTCGTCAGCTCACCGTGCCACCGGCGCAGGCCTACGGCGAGGCCGGTGCCGGCCACCAGCTGTCGGGTAA
GACGCTGGTATTCGTGATCGACCTGCTCGGCGCCCGCTAG

Upstream 100 bases:

>100_bases
CATCGGCCGTCGCGCAGGAAAGTCGTGGTGTGGACGGCAAGGTGGAACGGGTGGTGAGCAGACTGGCGGCCCACCGGCGG
CCGGACGATACGCTGCTGGC

Downstream 100 bases:

>100_bases
GGCTTCGCCAGGATCAATGCCCGGGGAGGCGCAGCACCAGCCGTGCGCCTCCCAATGGGCTCGACTCCAAAGCAGCTGTG
CCGCCATGGAGTTCGGCCTG

Product: putative peptidyl-prolyl cis-trans isomerase FkbP

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MTKPEIDFQPGPPPTELVIKDITVGDGAEATPGSVVDVHYVGVEFESGEEFDSSWNRGESIEFPLSALIKGWQDGIPGMK
VGGRRQLTVPPAQAYGEAGAGHQLSGKTLVFVIDLLGAR

Sequences:

>Translated_119_residues
MTKPEIDFQPGPPPTELVIKDITVGDGAEATPGSVVDVHYVGVEFESGEEFDSSWNRGESIEFPLSALIKGWQDGIPGMK
VGGRRQLTVPPAQAYGEAGAGHQLSGKTLVFVIDLLGAR
>Mature_118_residues
TKPEIDFQPGPPPTELVIKDITVGDGAEATPGSVVDVHYVGVEFESGEEFDSSWNRGESIEFPLSALIKGWQDGIPGMKV
GGRRQLTVPPAQAYGEAGAGHQLSGKTLVFVIDLLGAR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=42.8571428571429, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI150010552, Length=106, Percent_Identity=36.7924528301887, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI87082390, Length=101, Percent_Identity=42.5742574257426, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1789745, Length=105, Percent_Identity=38.0952380952381, Blast_Score=60, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540882, Length=91, Percent_Identity=40.6593406593407, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=86, Percent_Identity=48.8372093023256, Blast_Score=75, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324194, Length=102, Percent_Identity=41.1764705882353, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323566, Length=105, Percent_Identity=34.2857142857143, Blast_Score=61, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24647110, Length=100, Percent_Identity=43, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363946, Length=92, Percent_Identity=39.1304347826087, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17352457, Length=92, Percent_Identity=39.1304347826087, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12620; Mature: 12489

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPEIDFQPGPPPTELVIKDITVGDGAEATPGSVVDVHYVGVEFESGEEFDSSWNRGES
CCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
IEFPLSALIKGWQDGIPGMKVGGRRQLTVPPAQAYGEAGAGHQLSGKTLVFVIDLLGAR
CCCCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
TKPEIDFQPGPPPTELVIKDITVGDGAEATPGSVVDVHYVGVEFESGEEFDSSWNRGES
CCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCC
IEFPLSALIKGWQDGIPGMKVGGRRQLTVPPAQAYGEAGAGHQLSGKTLVFVIDLLGAR
CCCCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7522844; 12948626 [H]