Click here to switch to the map view.

The map label for this gene is pdxH [H]

Identifier: 169628030

GI number: 169628030

Start: 925989

End: 926627

Strand: Direct

Name: pdxH [H]

Synonym: MAB_0933

Alternate gene names: 169628030

Gene position: 925989-926627 (Clockwise)

Preceding gene: 169628027

Following gene: 169628031

Centisome position: 18.27

GC content: 66.51

Gene sequence:

>639_bases
GTGACCGAATGGCTGCGCTCTGACTACCGCCCCGGAGAAAAGGACGGCAGCGGCGATCTCGACGTCGACTGGCTCGCCGA
TGGCTGGCTTCCCCTGTTGCACAAATGGTTTGATCTCGCGGTGGCCTCGGGCATCCCGGAGCCGAACGCGATGGTGCTCG
CCACCGTCGACGACGGCCGACCGGTGACGCGCACGGTGCTGTGCAAGGGATTCGACGCAGCGGGTGTGACGTTCTTCTCA
AACTACGATTCCGCCAAGGGACGCCAGCTGGCTGCGACACCGTATGCGAGTGTCACCTTCCCCTGGTACGCGCTGGGGCG
CCAGGTCCATGTGCGTGGCCGGGTGACCAAGGTCGATCCGGCGCAGACCGCCGATTACTGGACCAATCGGCCGCGTGGAT
CACAGCTGGGCGCATGGGCTTCCCAGCAGTCCGCGCCCATCGAGTCGCGCGAGGCGCTGTTGGCCCAGCTTGGGGACGTC
ACCCAGCGGTTCGCGGGGCTGGATCAGATACCGGTGCCCCCACAGTGGGGCGGCTACGTCATCGCCCCCGAGACCGTCGA
GTTCTGGCAGGGACGGGAGAATCGAGTGCATAACCGGATCGTGGTGACCGACGGCCGGGTTGAACGGCTGCAGCCCTGA

Upstream 100 bases:

>100_bases
GTGGGTAACAACTCGGTAAAGGCGATTCTTGCACTCGCAAATAAGGGTGCTTCTTAGTCACCCCGCAGTGCCTTATCCGG
GCGCCTGTAGCGTGATTTTC

Downstream 100 bases:

>100_bases
CCTCATGTGGATCACTCTGCTGGTGATGGCGATCGCCGTCAGCTTCGAACCCTTCCGGCTGGGCATGACGGTGTTGATGC
TGAATCGGCCGCGCCCGATG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTEWLRSDYRPGEKDGSGDLDVDWLADGWLPLLHKWFDLAVASGIPEPNAMVLATVDDGRPVTRTVLCKGFDAAGVTFFS
NYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNRPRGSQLGAWASQQSAPIESREALLAQLGDV
TQRFAGLDQIPVPPQWGGYVIAPETVEFWQGRENRVHNRIVVTDGRVERLQP

Sequences:

>Translated_212_residues
MTEWLRSDYRPGEKDGSGDLDVDWLADGWLPLLHKWFDLAVASGIPEPNAMVLATVDDGRPVTRTVLCKGFDAAGVTFFS
NYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNRPRGSQLGAWASQQSAPIESREALLAQLGDV
TQRFAGLDQIPVPPQWGGYVIAPETVEFWQGRENRVHNRIVVTDGRVERLQP
>Mature_211_residues
TEWLRSDYRPGEKDGSGDLDVDWLADGWLPLLHKWFDLAVASGIPEPNAMVLATVDDGRPVTRTVLCKGFDAAGVTFFSN
YDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDPAQTADYWTNRPRGSQLGAWASQQSAPIESREALLAQLGDVT
QRFAGLDQIPVPPQWGGYVIAPETVEFWQGRENRVHNRIVVTDGRVERLQP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=172, Percent_Identity=44.1860465116279, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787926, Length=188, Percent_Identity=37.7659574468085, Blast_Score=148, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17553712, Length=191, Percent_Identity=37.696335078534, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6319509, Length=186, Percent_Identity=39.247311827957, Blast_Score=129, Evalue=3e-31,
Organism=Drosophila melanogaster, GI45551845, Length=176, Percent_Identity=39.7727272727273, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24644901, Length=176, Percent_Identity=39.7727272727273, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24644903, Length=146, Percent_Identity=31.5068493150685, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 23579; Mature: 23447

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEWLRSDYRPGEKDGSGDLDVDWLADGWLPLLHKWFDLAVASGIPEPNAMVLATVDDGR
CCCHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
PVTRTVLCKGFDAAGVTFFSNYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDP
CCEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCEEECCHHHCCCEEEECCEEEECCC
AQTADYWTNRPRGSQLGAWASQQSAPIESREALLAQLGDVTQRFAGLDQIPVPPQWGGYV
CHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
IAPETVEFWQGRENRVHNRIVVTDGRVERLQP
ECCCHHHHHCCCCCCCCCEEEEECCCHHCCCC
>Mature Secondary Structure 
TEWLRSDYRPGEKDGSGDLDVDWLADGWLPLLHKWFDLAVASGIPEPNAMVLATVDDGR
CCHHHHCCCCCCCCCCCCCEEHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCC
PVTRTVLCKGFDAAGVTFFSNYDSAKGRQLAATPYASVTFPWYALGRQVHVRGRVTKVDP
CCEEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCEEECCHHHCCCEEEECCEEEECCC
AQTADYWTNRPRGSQLGAWASQQSAPIESREALLAQLGDVTQRFAGLDQIPVPPQWGGYV
CHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
IAPETVEFWQGRENRVHNRIVVTDGRVERLQP
ECCCHHHHHCCCCCCCCCEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA