Click here to switch to the map view.

The map label for this gene is 169627989

Identifier: 169627989

GI number: 169627989

Start: 882671

End: 883873

Strand: Reverse

Name: 169627989

Synonym: MAB_0890c

Alternate gene names: NA

Gene position: 883873-882671 (Counterclockwise)

Preceding gene: 169627990

Following gene: 169627988

Centisome position: 17.44

GC content: 62.68

Gene sequence:

>1203_bases
GTGGCCCACTACATGCAGGTCGGATCAATTCCGCCCAAACGGCACACCCAACACCGCAATGCCGCGGGCAACCTCTACTA
CGAGGAACTCGTCGGTGAGGACGGATTCTCATCCGACTCAGCACTGCTGTATCACCGACACATTCCCGCGGCGATCGTGG
ACGCGACTCCGTGGGAGCTTCTCGATCATTCGACGTGTGCGAACCGGCCGCTAATACCGCGGCACCTTCGCCTCCACTCC
TTGTTTCCCCGCGACGCACTCGCCCACACCGACGTCGTCACCGGGCGGCGGCTCCTACTCGCCAATGCCGACGTACGTAT
CTATTACGTCGCGGCAGGTGCCGAATCCCCGCTGTATCGAAATGCGATTGGCGACGAGGTCGTCTACGTGGAGTCTGGGG
GCGGACTGGTCGAGACCGTGTTCGGTTGGCTGCGGGTACGCCAGGGTGACTACGTGGTGATCCCCCGCGCAACCACACAC
CGCTGGGTACCCGAGCCCGGTCAGCCGCTGCGCGCCTACATCATTGAGGCCAACAGCCACGTCGCCCCGCCGAAACGATA
TCTGTCCCGGTTCGGCCAGCTGCTCGAACATGCGCCGTACTGTGAGCGCGATCTGCACGGCCCGACCGATTTGATTTCCC
ATGACGCGACCGACGTCGACGTATTCGTGAAACACCGCGGCTCCCAAGGGATCACCGGGACACGCTACGTCTACGCCGAA
CACCCCTTCGACGTCGTCGGTTGGGACGGCTGCCTCTACCCCTACCGCTTCAACATCTCCGACTTCGAGCCGATAACCGG
GCGAGTCCACCAACCGCCGCCCGCCCACCAAGTCTTCGAAGCAAACAACTTCGTCATTTGCAATTTCGTACCGCGCAAGG
TCGACTACCACCCGTTGTCGGTGCCAGTTCCGTACTACCACTCCAACGTCGACTCCGACGAGGTGATGTTCTACGTCGGC
GGAGACTATGAAGCCCGCAAGGGGTCGGGAATCGCGCAGGGATCGGTCTCGGTTCATCCGGGCGGCCACGCCCACGGCCC
GCAGCGCGGAGCCTACGAAGCAAGTATCGGGATGGAATTCTTCGATGAACTCGCCGTCATGGTGGACACGTTCCGGCCAC
TGGAACTCGGTGAGGCGGCCCTAGCCTGCGACGATTCCACCTATGCGTGGAGTTGGGCGGGAAGGCGGCTGTCGCGCACA
TGA

Upstream 100 bases:

>100_bases
GCTCGTAACGGCCCGCCACCAACTGAGGCGTCCACCCCCATCGTCAATAGTTAATGTATGTACTATATTGATCCAGTACT
GACTCGACGCAGGAGGACCG

Downstream 100 bases:

>100_bases
TCTTTAGCCGATTGTTCGACGACGCCGCGCTGTTTCCCCCAGGAAACGCCCCAACCGACAGTGCGGTCCCAGCCCATCGC
GCCCATCTCGATGCCACCTA

Product: putative homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAHYMQVGSIPPKRHTQHRNAAGNLYYEELVGEDGFSSDSALLYHRHIPAAIVDATPWELLDHSTCANRPLIPRHLRLHS
LFPRDALAHTDVVTGRRLLLANADVRIYYVAAGAESPLYRNAIGDEVVYVESGGGLVETVFGWLRVRQGDYVVIPRATTH
RWVPEPGQPLRAYIIEANSHVAPPKRYLSRFGQLLEHAPYCERDLHGPTDLISHDATDVDVFVKHRGSQGITGTRYVYAE
HPFDVVGWDGCLYPYRFNISDFEPITGRVHQPPPAHQVFEANNFVICNFVPRKVDYHPLSVPVPYYHSNVDSDEVMFYVG
GDYEARKGSGIAQGSVSVHPGGHAHGPQRGAYEASIGMEFFDELAVMVDTFRPLELGEAALACDDSTYAWSWAGRRLSRT

Sequences:

>Translated_400_residues
MAHYMQVGSIPPKRHTQHRNAAGNLYYEELVGEDGFSSDSALLYHRHIPAAIVDATPWELLDHSTCANRPLIPRHLRLHS
LFPRDALAHTDVVTGRRLLLANADVRIYYVAAGAESPLYRNAIGDEVVYVESGGGLVETVFGWLRVRQGDYVVIPRATTH
RWVPEPGQPLRAYIIEANSHVAPPKRYLSRFGQLLEHAPYCERDLHGPTDLISHDATDVDVFVKHRGSQGITGTRYVYAE
HPFDVVGWDGCLYPYRFNISDFEPITGRVHQPPPAHQVFEANNFVICNFVPRKVDYHPLSVPVPYYHSNVDSDEVMFYVG
GDYEARKGSGIAQGSVSVHPGGHAHGPQRGAYEASIGMEFFDELAVMVDTFRPLELGEAALACDDSTYAWSWAGRRLSRT
>Mature_399_residues
AHYMQVGSIPPKRHTQHRNAAGNLYYEELVGEDGFSSDSALLYHRHIPAAIVDATPWELLDHSTCANRPLIPRHLRLHSL
FPRDALAHTDVVTGRRLLLANADVRIYYVAAGAESPLYRNAIGDEVVYVESGGGLVETVFGWLRVRQGDYVVIPRATTHR
WVPEPGQPLRAYIIEANSHVAPPKRYLSRFGQLLEHAPYCERDLHGPTDLISHDATDVDVFVKHRGSQGITGTRYVYAEH
PFDVVGWDGCLYPYRFNISDFEPITGRVHQPPPAHQVFEANNFVICNFVPRKVDYHPLSVPVPYYHSNVDSDEVMFYVGG
DYEARKGSGIAQGSVSVHPGGHAHGPQRGAYEASIGMEFFDELAVMVDTFRPLELGEAALACDDSTYAWSWAGRRLSRT

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17507969, Length=262, Percent_Identity=27.4809160305344, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24583650, Length=357, Percent_Identity=24.3697478991597, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR014710 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: NA

Molecular weight: Translated: 44755; Mature: 44623

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHYMQVGSIPPKRHTQHRNAAGNLYYEELVGEDGFSSDSALLYHRHIPAAIVDATPWEL
CCCEEECCCCCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCHHH
LDHSTCANRPLIPRHLRLHSLFPRDALAHTDVVTGRRLLLANADVRIYYVAAGAESPLYR
HCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCHHH
NAIGDEVVYVESGGGLVETVFGWLRVRQGDYVVIPRATTHRWVPEPGQPLRAYIIEANSH
HCCCCEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC
VAPPKRYLSRFGQLLEHAPYCERDLHGPTDLISHDATDVDVFVKHRGSQGITGTRYVYAE
CCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEC
HPFDVVGWDGCLYPYRFNISDFEPITGRVHQPPPAHQVFEANNFVICNFVPRKVDYHPLS
CCCEEECCCCEECEEEECCCCCCCCCCCCCCCCCCHHEEECCCEEEEEECCCCCCCCCCC
VPVPYYHSNVDSDEVMFYVGGDYEARKGSGIAQGSVSVHPGGHAHGPQRGAYEASIGMEF
CCCCHHCCCCCCCCEEEEECCCCCCCCCCCEECCEEEECCCCCCCCCCCCCEEHHCCHHH
FDELAVMVDTFRPLELGEAALACDDSTYAWSWAGRRLSRT
HHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCC
>Mature Secondary Structure 
AHYMQVGSIPPKRHTQHRNAAGNLYYEELVGEDGFSSDSALLYHRHIPAAIVDATPWEL
CCEEECCCCCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCEEEEEECCCEEEECCCCHHH
LDHSTCANRPLIPRHLRLHSLFPRDALAHTDVVTGRRLLLANADVRIYYVAAGAESPLYR
HCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEECCCEEEEEEEECCCCCHHH
NAIGDEVVYVESGGGLVETVFGWLRVRQGDYVVIPRATTHRWVPEPGQPLRAYIIEANSH
HCCCCEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCC
VAPPKRYLSRFGQLLEHAPYCERDLHGPTDLISHDATDVDVFVKHRGSQGITGTRYVYAE
CCCHHHHHHHHHHHHHHCCCCHHCCCCCHHHHCCCCCCEEEEEEECCCCCCCCEEEEEEC
HPFDVVGWDGCLYPYRFNISDFEPITGRVHQPPPAHQVFEANNFVICNFVPRKVDYHPLS
CCCEEECCCCEECEEEECCCCCCCCCCCCCCCCCCHHEEECCCEEEEEECCCCCCCCCCC
VPVPYYHSNVDSDEVMFYVGGDYEARKGSGIAQGSVSVHPGGHAHGPQRGAYEASIGMEF
CCCCHHCCCCCCCCEEEEECCCCCCCCCCCEECCEEEECCCCCCCCCCCCCEEHHCCHHH
FDELAVMVDTFRPLELGEAALACDDSTYAWSWAGRRLSRT
HHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726 [H]