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The map label for this gene is lip2 [H]

Identifier: 169627925

GI number: 169627925

Start: 822326

End: 823216

Strand: Reverse

Name: lip2 [H]

Synonym: MAB_0826c

Alternate gene names: 169627925

Gene position: 823216-822326 (Counterclockwise)

Preceding gene: 169627934

Following gene: 169627919

Centisome position: 16.25

GC content: 65.77

Gene sequence:

>891_bases
GTGTCGTCGCCTGACATTCATCCCGATCTCCGCTTGGCAGCCAGGGCATTTCCGCGACAGGTCGGCCTGCCGCGAACCCT
CTCGATACTGCGTGCGAGCATTTACCTCACCGATCTGCTGCCCCGGCACGGGGTGCGGCGCATCGCGGTCAACGACAACG
TGACGGTCCGGGCACATGTTCCCAAGAACCTCGAAGAACCGTCCGCGGCGCTGTTGTGGATTCACGGCGGCGGCTACGTG
ATGGGTACCGCACGTCAGGACGACTTTTTCTGCCGCAAGGTGATGCACGAAACCGGGATACCGGTCGTGTCGGTCGACTA
TCGACTGGCACCCGAGCACCCTTACCCCATTCCACTCGAGGACTGCTACGCCGCGCTGCGCTGGCTGTCCGTGCAGGGAT
GGATCGATCCGACGCGCATCGCCGTCGGCGGCGCCAGTGCCGGTGGCGGACTGGCCGCGGCGCTTGCGCTCCTGGCCCGC
GACCGTGGCGAGGTAGCTCCCGCCGCACAGCTGCTGATCTACCCCATGCTCGACGACCGCTCCAGTGAGCGCACGGATAT
CGACGGAACAAATCTGCGGCTATGGAGCGGAGACAGCAACCGGTTTGGCTGGGATTCCTATCTGGGCGACGCGGATCGCG
ATATCGCCGTACCCGGCCGTCGCACCGATGTGGCGGGACTGGCGCCTGCCTGGATTGGCATCGGAACGGCCGACCTGTTT
CACGACGAGGATCTGGCGTATGCCGAACGCCTACGCACCGCCGGGGTCCCGTGCGAGCTGGAGGTGGTGCCCGGCGCATT
TCACGGCTTCGACAAACTCGTGCCGTGGGCAGGAGTGTCCAGGGACTTCGTGGCAAAGGCGTGCCGCAGCCTGTTGGGCG
CGCTGAGCTGA

Upstream 100 bases:

>100_bases
CCTTCCGTAGATACATGACTTTCAAGCGGACTGGGGTCCGAAACATTCCCCGTCACACCAAACAGCCGCGGTGTGTACAC
ACCACGGGCATACTCGCTAT

Downstream 100 bases:

>100_bases
CCCGATCTTCGCGGCCGGCTTACACAACTTCCCGTGACATGAACTATCCCAACAGCGCCCGAGCACGGATGGCGATCCAC
AGAGCAGCCCGGGTGTCCGC

Product: esterase LipW

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSSPDIHPDLRLAARAFPRQVGLPRTLSILRASIYLTDLLPRHGVRRIAVNDNVTVRAHVPKNLEEPSAALLWIHGGGYV
MGTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPIPLEDCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLAR
DRGEVAPAAQLLIYPMLDDRSSERTDIDGTNLRLWSGDSNRFGWDSYLGDADRDIAVPGRRTDVAGLAPAWIGIGTADLF
HDEDLAYAERLRTAGVPCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS

Sequences:

>Translated_296_residues
MSSPDIHPDLRLAARAFPRQVGLPRTLSILRASIYLTDLLPRHGVRRIAVNDNVTVRAHVPKNLEEPSAALLWIHGGGYV
MGTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPIPLEDCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLAR
DRGEVAPAAQLLIYPMLDDRSSERTDIDGTNLRLWSGDSNRFGWDSYLGDADRDIAVPGRRTDVAGLAPAWIGIGTADLF
HDEDLAYAERLRTAGVPCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS
>Mature_295_residues
SSPDIHPDLRLAARAFPRQVGLPRTLSILRASIYLTDLLPRHGVRRIAVNDNVTVRAHVPKNLEEPSAALLWIHGGGYVM
GTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPIPLEDCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLARD
RGEVAPAAQLLIYPMLDDRSSERTDIDGTNLRLWSGDSNRFGWDSYLGDADRDIAVPGRRTDVAGLAPAWIGIGTADLFH
DEDLAYAERLRTAGVPCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=289, Percent_Identity=29.0657439446367, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI206597554, Length=136, Percent_Identity=35.2941176470588, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI21328446, Length=118, Percent_Identity=34.7457627118644, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI157041239, Length=166, Percent_Identity=30.7228915662651, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI68051721, Length=138, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786682, Length=231, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72001146, Length=177, Percent_Identity=33.8983050847458, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567059, Length=207, Percent_Identity=29.951690821256, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71996133, Length=154, Percent_Identity=30.5194805194805, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17540028, Length=129, Percent_Identity=32.5581395348837, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 32180; Mature: 32049

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPDIHPDLRLAARAFPRQVGLPRTLSILRASIYLTDLLPRHGVRRIAVNDNVTVRAHV
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEC
PKNLEEPSAALLWIHGGGYVMGTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPIPLE
CCCCCCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHH
DCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLARDRGEVAPAAQLLIYPMLDDR
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
SSERTDIDGTNLRLWSGDSNRFGWDSYLGDADRDIAVPGRRTDVAGLAPAWIGIGTADLF
CCCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCHHHHCCCHHHHH
HDEDLAYAERLRTAGVPCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS
CCCHHHHHHHHHHCCCCEEEEECCCCHHCHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSPDIHPDLRLAARAFPRQVGLPRTLSILRASIYLTDLLPRHGVRRIAVNDNVTVRAHV
CCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEC
PKNLEEPSAALLWIHGGGYVMGTARQDDFFCRKVMHETGIPVVSVDYRLAPEHPYPIPLE
CCCCCCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHH
DCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLARDRGEVAPAAQLLIYPMLDDR
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
SSERTDIDGTNLRLWSGDSNRFGWDSYLGDADRDIAVPGRRTDVAGLAPAWIGIGTADLF
CCCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCHHHHCCCHHHHH
HDEDLAYAERLRTAGVPCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS
CCCHHHHHHHHHHCCCCEEEEECCCCHHCHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]