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The map label for this gene is tcmP [H]

Identifier: 169627771

GI number: 169627771

Start: 670794

End: 671600

Strand: Reverse

Name: tcmP [H]

Synonym: MAB_0668c

Alternate gene names: 169627771

Gene position: 671600-670794 (Counterclockwise)

Preceding gene: 169627775

Following gene: 169627754

Centisome position: 13.25

GC content: 61.83

Gene sequence:

>807_bases
ATGTCTGGCATCGATGTTCGCCATCTCGACGGCGTGTCCGAGACCGCGCTGCTGACCTTGCATCAACGAGCAACTGAAGC
AGCGCGCACGGACGGCATCCTCGACGACCCGATGGCCATCTCGCTACACGCCAGCGTCGACTACGATTTTGCGCACTTCG
GTCGTACCCATCAGGCTACAGCCTTGCGCGCCTTGATATTCGACAAGGCGACACGGGAATACCTGGACTACCACCCCTGC
GCCACCGTGGTGGCGTTGGCCGAGGGACTGCAGACCAGTTTCTGGCGCGTCGACAACGGCCGGCTAACCTGGCTCTCGGT
AGACCTGGAGCCCATTGTGCGGTTGCGGCAGCGGCTCCTTCCGCGATCGGAGCGGTTGTCTCACTGCGCCCAATCAGCGT
TGGACTACTCGTGGATGGACAGGGTCGACGACTCCGCGGGTGTGCTGATCACCGCGGAGGGCCTGTTCCAGTACCTGGAG
CGCGATCTGGTATTTGACCTGATATCGGTCTGTGCGCAACGCTTTCCGGGCGGCAGGCTGATTTTTGATTCGGTACCTAA
ATTCCTGAGCACGCATTCACAGCGCGGCATACGGCTCAGTGAGCAGTACGTTGTTCCGCCAATGCCATTCTCGTTCACCG
CGAATCAATACGACGAACTACGCGCCATTCCCGGCATCCGCAGTGTTCGGGAGCTACGGATGCCGGCAGGGCGCGGCAAG
GTACTGCGCTGGGCGGCTCCGTTGCTGTACGCGCTACCCGGCCTCGACCGGTGGCGCGCACCTCATACCGTTGTCGAGTT
CGGCTGA

Upstream 100 bases:

>100_bases
CAGAAAGTTCCCGAACAATCAGAATCAGCGTCGGAAATCACATTTATCGTTGTGCGCCACGAATTCCCACTCGCGCGTGC
CGTCCCGTACAGTCGGGCCC

Downstream 100 bases:

>100_bases
GGCATCAGCAATTCGGCTTGCCCTGGCTATCCTGCGGCCACGGCGAAATCGCCACCGGCCCGCACGAGCGTGTCATGAAC
CTCTTCGACAGAGAGCACGC

Product: O-methyltransferase OmT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQATALRALIFDKATREYLDYHPC
ATVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLLPRSERLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLE
RDLVFDLISVCAQRFPGGRLIFDSVPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQYDELRAIPGIRSVRELRMPAGRGK
VLRWAAPLLYALPGLDRWRAPHTVVEFG

Sequences:

>Translated_268_residues
MSGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQATALRALIFDKATREYLDYHPC
ATVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLLPRSERLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLE
RDLVFDLISVCAQRFPGGRLIFDSVPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQYDELRAIPGIRSVRELRMPAGRGK
VLRWAAPLLYALPGLDRWRAPHTVVEFG
>Mature_267_residues
SGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQATALRALIFDKATREYLDYHPCA
TVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLLPRSERLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLER
DLVFDLISVCAQRFPGGRLIFDSVPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQYDELRAIPGIRSVRELRMPAGRGKV
LRWAAPLLYALPGLDRWRAPHTVVEFG

Specific function: O-methyltransferase that catalyzes the methylation of the C-9 carboxy group of tetracenomycin E (TCM E) to yield TCM A2. Catalyzes as well the following side reactions:methylation of 8- O-methyl-TCM D3 to 9-carboxymethyl-8-O-methyl-TCM D3; and of TCM B3 t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007213
- InterPro:   IPR016874 [H]

Pfam domain/function: PF04072 LCM [H]

EC number: NA

Molecular weight: Translated: 30262; Mature: 30131

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQAT
CCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCHHHH
ALRALIFDKATREYLDYHPCATVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEECCCEEEEEEECHHHHHHHHHHHC
PRSERLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLERDLVFDLISVCAQRFPGGRL
CHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFDSVPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQYDELRAIPGIRSVRELRMPAGRGK
HHHHHHHHHHHHHHCCCEECCCEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCC
VLRWAAPLLYALPGLDRWRAPHTVVEFG
HHHHHHHHHHHCCCCHHHCCCCCEEECC
>Mature Secondary Structure 
SGIDVRHLDGVSETALLTLHQRATEAARTDGILDDPMAISLHASVDYDFAHFGRTHQAT
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHCCCCHHHH
ALRALIFDKATREYLDYHPCATVVALAEGLQTSFWRVDNGRLTWLSVDLEPIVRLRQRLL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEECCCEEEEEEECHHHHHHHHHHHC
PRSERLSHCAQSALDYSWMDRVDDSAGVLITAEGLFQYLERDLVFDLISVCAQRFPGGRL
CHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFDSVPKFLSTHSQRGIRLSEQYVVPPMPFSFTANQYDELRAIPGIRSVRELRMPAGRGK
HHHHHHHHHHHHHHCCCEECCCEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCCCCCC
VLRWAAPLLYALPGLDRWRAPHTVVEFG
HHHHHHHHHHHCCCCHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8509339 [H]