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The map label for this gene is tauD [C]

Identifier: 169627762

GI number: 169627762

Start: 662139

End: 663008

Strand: Direct

Name: tauD [C]

Synonym: MAB_0659

Alternate gene names: 169627762

Gene position: 662139-663008 (Clockwise)

Preceding gene: 169627761

Following gene: 169627763

Centisome position: 13.07

GC content: 60.92

Gene sequence:

>870_bases
ATGACGCTCAACGTGAAGGGCGAGGGACTGGGGGCGCAGGTCACCGGGATTGATCCAGGCAACCTGGATGGCATTACCAC
CGAGGAGATCCGCGAACTCGTCTACCGGCACAAGCTCGTCGTCCTCAAGGGCGTGCACCCCACGCCCGAGCAATTCATTG
AGCTCGGCAGATTGATCGGCGAGATCGTGCCCTACTACGAACCCGTCTACCATCATCAAGACCACCCGGAGATCTTCGTG
TCTTCTACCGAGGAGGGGCAAGGGGTTCCGCGCACAGGTGCGTTCTGGCATGTCGACTACATGTTCATGCCGAAGCCTTT
CGCCTTCTCCATGGTGTTGCCATTGGCGGTACCTGGGCATGACCGTGGTACCTACTTCATCGATCTCAGCAAGGTATGGG
AATCGCTGCCTGCAAAGACAAAAGACGCCGCACTCGGAACATTCAGCACACATACCCCGCGCCGCTACATCAAGATCCGC
CCGAGTGATGTATACCGGCCTATCGGTGAGATCCTGGCGGAGATCGAGCGAACCACTCCTCCGCAGAAGTGGCCGACGGT
GATCAAGCACCCGAAGACAGGGGAGGAGATCCTCTACATCTGCGAGGCGGGCACCGAGACCATCGAGGACGGGGCCGGCC
GGATACAGGACGCCGCGCTGCTGCAGCAGCTCCTCGAGGCTTCGGGCCAGCTCGACCCGGACTACGCGTCGCCGTTCATC
CACGCCCAGCACTACGAAGTCGGGGATATCGTATTGTGGGACAACCGCTCTCTTGTGCACCGTGCGAAGCATGGGACAGC
ATCGGGCACGTTGACCACCTACCGTCTGACCATGCTGGACGGACTCGAGGCTCCGGGGTTCGCGGCGTGA

Upstream 100 bases:

>100_bases
GCAACCGGTCTCTATTTTCCTGGGAACTTTTCGTACGCCGGGATCGACTGCTCCCTTAGTCGCATTAGTTGGTCATATCC
GCGAGAAGGTTAGGGAGTCG

Downstream 100 bases:

>100_bases
GCGCGGTCGCCGCAACACTGTCGGTACAGACCGGACTGCCGTCGGCGGGCATGGTGCCGATGTCCGCGGCCTTGCTCAGC
AGGGTTCTCGAACCGTATTC

Product: putative dioxygenase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIGEIVPYYEPVYHHQDHPEIFV
SSTEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALGTFSTHTPRRYIKIR
PSDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFI
HAQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA

Sequences:

>Translated_289_residues
MTLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIGEIVPYYEPVYHHQDHPEIFV
SSTEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALGTFSTHTPRRYIKIR
PSDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFI
HAQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA
>Mature_288_residues
TLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIGEIVPYYEPVYHHQDHPEIFVS
STEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALGTFSTHTPRRYIKIRP
SDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFIH
AQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=284, Percent_Identity=26.056338028169, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 32193; Mature: 32062

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIG
CEEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHH
EIVPYYEPVYHHQDHPEIFVSSTEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGH
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCC
DRGTYFIDLSKVWESLPAKTKDAALGTFSTHTPRRYIKIRPSDVYRPIGEILAEIERTTP
CCCEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
PQKWPTVIKHPKTGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFI
CCCCCHHHCCCCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
HAQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA
EECCCCCCCEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIG
EEECCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHH
EIVPYYEPVYHHQDHPEIFVSSTEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGH
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEEECCCC
DRGTYFIDLSKVWESLPAKTKDAALGTFSTHTPRRYIKIRPSDVYRPIGEILAEIERTTP
CCCEEEEEHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
PQKWPTVIKHPKTGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFI
CCCCCHHHCCCCCCCEEEEEECCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
HAQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA
EECCCCCCCEEEECCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]