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The map label for this gene is ybbO [C]

Identifier: 169627749

GI number: 169627749

Start: 648123

End: 649046

Strand: Reverse

Name: ybbO [C]

Synonym: MAB_0646c

Alternate gene names: 169627749

Gene position: 649046-648123 (Counterclockwise)

Preceding gene: 169627752

Following gene: 169627748

Centisome position: 12.81

GC content: 64.39

Gene sequence:

>924_bases
ATGTCGCGATCCACCACCAAATGGAGCACCACCGACATCCCCGATCAGACCGGCCGCATCGCTATCGTCACCGGTGCCAA
TACCGGACTCGGCCTCGAAACCGCCAAGGCACTCGCCGCGCACGGCGCTCACGTGGTACTCGCCGTCCGCAACGCGGAGA
AAGGAAAAGCCGCGGCTGAGGCGATCACCGCGGCCCACTCAAACGCCGATGTCACCCTGCAGTCATTGGACCTTTCCTCA
CTGGAATCCGTCCGCCGGGCCAGTGATGAGCTCAAGGGGCGCTACGACAAGATCGATCTGCTGATCAACAACGCCGGCGT
CATGTGGACGGAAAAGTCCAGCACCGCCGACGGCTTCGAGCTGCAGTTCGGCACCAATCACCTGGGCCATTACGCACTCA
CCGGCCTGCTCTTGGAGCGCCTGTTGCCCGTGGAGGGCTCACGCGTGGTGACGGTCAGCAGCATCGGGCACCGCATCCGC
GCCGACATCCACTTCGATGACCTGCAATGGGAACGCGACTACGACCGTGTCGCGGCATATGGACAGTCGAAGCTGGCCAA
CCTGTTGTTCACCTACGAGCTACAGCGGCGCCTGGCCGGCACCAACACCGTCGCCCTGGCCGCGCATCCCGGTGGCTCCA
ATACCGAACTGGCCCGCAATTCTCCGCTGTGGGTCCGGGCGGTGTTCGACGTCGTGGCGCCGGTATTGGTCCAGGGAGCG
GATATGGGTGCCCTGCCCACGCTGCGAGCCGCCACCGACCCGGCTGCCCTGGGCGGCCAGTACTACGGGCCCGACGGATT
CATGGAACAGCGCGGTAACCCCAAGGTCGTCGCGTCGAGCGAACAGTCCTACAACCTCGATTTGCAGCGTCGGCTGTGGT
CGGTATCCGAGGAACTCACCGACGTGGTCTTCCCGGTCAAGTGA

Upstream 100 bases:

>100_bases
TCTCACACTCCTTGACGCCTTGACAAAACGGGGCGAGCGTTCCGTATATTTACAAGCGGAGTAACCGCCCCGGTTACTGA
CAGACTATCAAGGAGCACCC

Downstream 100 bases:

>100_bases
GCTGAGCCGGTGGTGGCGAGCGCTGTGCTGATCGTCTCCAGCTATCACTCTGGTGACACGACACGCGGTGCTCGCCACGC
CCGTCGGGATGCACTCCCGT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAEAITAAHSNADVTLQSLDLSS
LESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIR
ADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRRLAGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGA
DMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELTDVVFPVK

Sequences:

>Translated_307_residues
MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAEAITAAHSNADVTLQSLDLSS
LESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIR
ADIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRRLAGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGA
DMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELTDVVFPVK
>Mature_306_residues
SRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAEAITAAHSNADVTLQSLDLSSL
ESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFELQFGTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIRA
DIHFDDLQWERDYDRVAAYGQSKLANLLFTYELQRRLAGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGAD
MGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELTDVVFPVK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=304, Percent_Identity=39.8026315789474, Blast_Score=185, Evalue=6e-47,
Organism=Homo sapiens, GI166795268, Length=293, Percent_Identity=41.296928327645, Blast_Score=184, Evalue=6e-47,
Organism=Homo sapiens, GI186928839, Length=287, Percent_Identity=42.1602787456446, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI193804850, Length=299, Percent_Identity=39.4648829431438, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI10190746, Length=303, Percent_Identity=37.6237623762376, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI7706523, Length=295, Percent_Identity=36.271186440678, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI19923931, Length=260, Percent_Identity=38.4615384615385, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI146231950, Length=253, Percent_Identity=38.3399209486166, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI7705421, Length=236, Percent_Identity=29.6610169491525, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI13375997, Length=191, Percent_Identity=30.8900523560209, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI72534732, Length=165, Percent_Identity=31.5151515151515, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI20149619, Length=208, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4502601, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532805, Length=301, Percent_Identity=33.8870431893688, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17532791, Length=306, Percent_Identity=31.0457516339869, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193207620, Length=305, Percent_Identity=31.1475409836066, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17558006, Length=285, Percent_Identity=32.280701754386, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17505416, Length=307, Percent_Identity=30.9446254071661, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71992402, Length=300, Percent_Identity=31.3333333333333, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI72001364, Length=214, Percent_Identity=37.8504672897196, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17535059, Length=298, Percent_Identity=30.5369127516779, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI115533174, Length=290, Percent_Identity=27.9310344827586, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533172, Length=290, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI32565532, Length=136, Percent_Identity=36.7647058823529, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324820, Length=284, Percent_Identity=30.6338028169014, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI28573296, Length=296, Percent_Identity=43.5810810810811, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI22024069, Length=292, Percent_Identity=41.4383561643836, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19921754, Length=298, Percent_Identity=40.6040268456376, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI161076371, Length=257, Percent_Identity=42.8015564202335, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24586328, Length=296, Percent_Identity=39.8648648648649, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI45554248, Length=250, Percent_Identity=42.4, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24640117, Length=250, Percent_Identity=42.4, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI20129347, Length=296, Percent_Identity=34.4594594594595, Blast_Score=143, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24647946, Length=248, Percent_Identity=33.8709677419355, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI45553409, Length=248, Percent_Identity=33.8709677419355, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24647948, Length=248, Percent_Identity=33.8709677419355, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656154, Length=280, Percent_Identity=32.8571428571429, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI19922628, Length=280, Percent_Identity=32.8571428571429, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24647931, Length=304, Percent_Identity=33.8815789473684, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=26.9230769230769, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357041, Length=213, Percent_Identity=29.1079812206573, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33153; Mature: 33021

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAE
CCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHH
AITAAHSNADVTLQSLDLSSLESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFE
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCCCCCEE
LQFGTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIRADIHFDDLQWERDYDRVAAY
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHH
GQSKLANLLFTYELQRRLAGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGA
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELT
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
DVVFPVK
HHEECCC
>Mature Secondary Structure 
SRSTTKWSTTDIPDQTGRIAIVTGANTGLGLETAKALAAHGAHVVLAVRNAEKGKAAAE
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHH
AITAAHSNADVTLQSLDLSSLESVRRASDELKGRYDKIDLLINNAGVMWTEKSSTADGFE
HHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEECCCCCCCCEE
LQFGTNHLGHYALTGLLLERLLPVEGSRVVTVSSIGHRIRADIHFDDLQWERDYDRVAAY
EEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEEECCCCCCCCHHHHHHH
GQSKLANLLFTYELQRRLAGTNTVALAAHPGGSNTELARNSPLWVRAVFDVVAPVLVQGA
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DMGALPTLRAATDPAALGGQYYGPDGFMEQRGNPKVVASSEQSYNLDLQRRLWSVSEELT
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
DVVFPVK
HHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]