BacMap

Definition	Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence.
Accession	NC_010397
Length	5,067,172

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The map label for this gene is znuC [C]

Identifier: 169627679

GI number: 169627679

Start: 575026

End: 575811

Strand: Reverse

Name: znuC [C]

Synonym: MAB_0576c

Alternate gene names: 169627679

Gene position: 575811-575026 (Counterclockwise)

Preceding gene: 169627680

Following gene: 169627678

Centisome position: 11.36

GC content: 63.1

Gene sequence:

>786_bases
ATGAGTGCCGCGACGCTGCGCGACGCATCGCTGAATCGCGGTGGACGCACCCTTTGGCAGGGTTTGGATCTCACGGTGGA
ACCCGGTGAGTTCATCGCCGTACTGGGACCCAATGGTTCCGGGAAAACCTCGCTGCTACGCCTGCTTTTGGGCCAGGTGC
CGCTCACCCGCGGCAGCATGACCGTCACCAGCGACCTCGGATACGTACCCCAGCACCGACTCGCCGACAACGCACTTATC
CTGCGCGCGGAGGATCTGGTGGGACTCGGAATCGACGGGCACCGCTGGGGATTGGCGTCATTCAACCCGGCTCGCCGGGC
CCGTTATCGTGCGGCGGTCGACCTCGCGCTGAATCAGGTGGACGCAAGCCATCTGGCGACCAAGGCCGTCTCGTCGCTGT
CCGGCGGCGAGCTGCAGCGGGTGCGCATCGCGCAGGCATTGGCCGGTGATCCTGCACTGCTGCTTTGCGATGAGCCCCTG
CTCAACTTGGACCCAGCAAGCGCACAACAGATCTGTGCCCTGATCGACAAGCGACGATGCGACGCGCAGACGGCAGTGCT
GTTCGTGACACACGAGATCAATCCGATCGTGCCGTACGTGGACAGGATCCTGTACCTGGTGGATGGACGCTTTCAGATCG
GCACCGTCGACGAGGTGATGACGACCGAGACGTTGTCGGAGCTGTACCGGGCGCAGATCGATGTGGTGAAGATACGCGGA
CAGTATGTGGTGGTGGGCGAAGACCGGCAGATCACCGCAGAGTGTGCCGAGCACGCCCATGAATAA

Upstream 100 bases:

>100_bases
GGCACCGACTACGTCACCTGGCAGCGACGCACCACCGAACAGCTCGCCGCGGCCCTGGGATGAGCCGCGTGCGCGAAGAC
CAGTAGCGGATAATGACCGC

Downstream 100 bases:

>100_bases
CTTCTTCGATCTGTCGCTTACCGCCGATCTACTCGGGCGCGACTTCGTGCAACAGGCGATTTTGGCGGCCGCGCTCCTCG
GACTGCTGGCGGGGCTCATC

Product: putative ABC transporter ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSAATLRDASLNRGGRTLWQGLDLTVEPGEFIAVLGPNGSGKTSLLRLLLGQVPLTRGSMTVTSDLGYVPQHRLADNALI
LRAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQVDASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPL
LNLDPASAQQICALIDKRRCDAQTAVLFVTHEINPIVPYVDRILYLVDGRFQIGTVDEVMTTETLSELYRAQIDVVKIRG
QYVVVGEDRQITAECAEHAHE

Sequences:

>Translated_261_residues
MSAATLRDASLNRGGRTLWQGLDLTVEPGEFIAVLGPNGSGKTSLLRLLLGQVPLTRGSMTVTSDLGYVPQHRLADNALI
LRAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQVDASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPL
LNLDPASAQQICALIDKRRCDAQTAVLFVTHEINPIVPYVDRILYLVDGRFQIGTVDEVMTTETLSELYRAQIDVVKIRG
QYVVVGEDRQITAECAEHAHE
>Mature_260_residues
SAATLRDASLNRGGRTLWQGLDLTVEPGEFIAVLGPNGSGKTSLLRLLLGQVPLTRGSMTVTSDLGYVPQHRLADNALIL
RAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQVDASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPLL
NLDPASAQQICALIDKRRCDAQTAVLFVTHEINPIVPYVDRILYLVDGRFQIGTVDEVMTTETLSELYRAQIDVVKIRGQ
YVVVGEDRQITAECAEHAHE

Specific function: Involved In The High-Affinity Zinc Uptake Transport System. [C]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI66529005, Length=211, Percent_Identity=32.2274881516588, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI27436953, Length=207, Percent_Identity=27.0531400966184, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI153792144, Length=207, Percent_Identity=26.0869565217391, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=26.0663507109005, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI9955970, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI157502201, Length=204, Percent_Identity=30.3921568627451, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI157502203, Length=204, Percent_Identity=29.9019607843137, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27881501, Length=210, Percent_Identity=25.2380952380952, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=25.2380952380952, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4557481, Length=214, Percent_Identity=28.5046728971963, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI27477115, Length=214, Percent_Identity=25.7009345794392, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI45446740, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI47078218, Length=203, Percent_Identity=26.6009852216749, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI21536376, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI6005701, Length=218, Percent_Identity=23.394495412844, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI27262624, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI27262626, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI116734710, Length=209, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI150417984, Length=207, Percent_Identity=27.0531400966184, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI105990541, Length=208, Percent_Identity=25.9615384615385, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788165, Length=207, Percent_Identity=32.3671497584541, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786345, Length=238, Percent_Identity=32.7731092436975, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786563, Length=198, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790739, Length=249, Percent_Identity=30.1204819277108, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788225, Length=229, Percent_Identity=32.7510917030568, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789593, Length=244, Percent_Identity=28.6885245901639, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790544, Length=236, Percent_Identity=30.9322033898305, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=31.1627906976744, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787712, Length=201, Percent_Identity=32.3383084577114, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790467, Length=228, Percent_Identity=27.1929824561404, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=29.9065420560748, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786253, Length=214, Percent_Identity=31.3084112149533, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788761, Length=255, Percent_Identity=29.0196078431373, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789032, Length=208, Percent_Identity=29.3269230769231, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786803, Length=240, Percent_Identity=28.3333333333333, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1787164, Length=203, Percent_Identity=33.9901477832512, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=30.8411214953271, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1789873, Length=227, Percent_Identity=32.15859030837, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=31.0679611650485, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082267, Length=203, Percent_Identity=29.064039408867, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789672, Length=226, Percent_Identity=28.7610619469027, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081791, Length=223, Percent_Identity=28.6995515695067, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787500, Length=257, Percent_Identity=26.4591439688716, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790190, Length=220, Percent_Identity=26.8181818181818, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789891, Length=209, Percent_Identity=28.7081339712919, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1788506, Length=225, Percent_Identity=30.2222222222222, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786398, Length=237, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789864, Length=219, Percent_Identity=26.4840182648402, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI145693107, Length=226, Percent_Identity=29.2035398230088, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48995001, Length=223, Percent_Identity=24.6636771300448, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1787758, Length=229, Percent_Identity=25.3275109170306, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786872, Length=191, Percent_Identity=29.8429319371728, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=221, Percent_Identity=27.6018099547511, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790525, Length=211, Percent_Identity=26.0663507109005, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787792, Length=226, Percent_Identity=25.6637168141593, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=203, Percent_Identity=29.064039408867, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=216, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17556528, Length=227, Percent_Identity=28.6343612334802, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=249, Percent_Identity=26.9076305220884, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32566680, Length=158, Percent_Identity=33.5443037974684, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115532730, Length=192, Percent_Identity=28.125, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146765, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992066, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86564969, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71992070, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=216, Percent_Identity=24.0740740740741, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538654, Length=214, Percent_Identity=23.8317757009346, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45552343, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552359, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550972, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552357, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552349, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552341, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552363, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552345, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552351, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552335, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552355, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552353, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552347, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552339, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45552361, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45552337, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24583969, Length=222, Percent_Identity=27.9279279279279, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643674, Length=211, Percent_Identity=27.0142180094787, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24585557, Length=207, Percent_Identity=28.0193236714976, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45552437, Length=207, Percent_Identity=28.0193236714976, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45550390, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574150, Length=224, Percent_Identity=25.8928571428571, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007328, Length=224, Percent_Identity=25.8928571428571, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI85725262, Length=188, Percent_Identity=29.7872340425532, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24666092, Length=211, Percent_Identity=26.0663507109005, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI221512771, Length=213, Percent_Identity=27.2300469483568, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574259, Length=208, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649703, Length=232, Percent_Identity=26.7241379310345, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62484234, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161078426, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17136592, Length=208, Percent_Identity=27.4038461538462, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24585091, Length=207, Percent_Identity=27.0531400966184, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24648279, Length=177, Percent_Identity=29.9435028248588, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28313; Mature: 28182

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAATLRDASLNRGGRTLWQGLDLTVEPGEFIAVLGPNGSGKTSLLRLLLGQVPLTRGSM
CCCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCE
TVTSDLGYVPQHRLADNALILRAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQV
EEECCCCCCCCHHCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPLLNLDPASAQQICALIDKRRC
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
DAQTAVLFVTHEINPIVPYVDRILYLVDGRFQIGTVDEVMTTETLSELYRAQIDVVKIRG
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEEEECC
QYVVVGEDRQITAECAEHAHE
EEEEEECCCCHHHHHHHCCCC
>Mature Secondary Structure 
SAATLRDASLNRGGRTLWQGLDLTVEPGEFIAVLGPNGSGKTSLLRLLLGQVPLTRGSM
CCCCCCCCCCCCCCHHHHCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCE
TVTSDLGYVPQHRLADNALILRAEDLVGLGIDGHRWGLASFNPARRARYRAAVDLALNQV
EEECCCCCCCCHHCCCCEEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DASHLATKAVSSLSGGELQRVRIAQALAGDPALLLCDEPLLNLDPASAQQICALIDKRRC
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
DAQTAVLFVTHEINPIVPYVDRILYLVDGRFQIGTVDEVMTTETLSELYRAQIDVVKIRG
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEEEECC
QYVVVGEDRQITAECAEHAHE
EEEEEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]