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The map label for this gene is ispD [H]

Identifier: 169627672

GI number: 169627672

Start: 568895

End: 569527

Strand: Direct

Name: ispD [H]

Synonym: MAB_0569

Alternate gene names: 169627672

Gene position: 568895-569527 (Clockwise)

Preceding gene: 169627671

Following gene: 169627673

Centisome position: 11.23

GC content: 66.67

Gene sequence:

>633_bases
GTGCGGCTGGGTGCAAATACCCCGAAGGCCTTCGTGAGTGTCGGCGGCCGGACCATGCTTCAGCGTTGTGTGGACGGCCT
GCTCGCATCCGGGGCCGTGGACGAGGTAGTGGTCGTGGTCGGTGCCGATCAGCTCGAGAGGGCCGCTGCCCTGGTGGGCT
CCGGGGCCACCGTTGTGCAGGGCGGTGCCGAGCGCACCGACTCGGTGCGGGCCGGTTTGGCCGCCGTGGATGCGGCCGAC
TGGATTCTGGTTCACGATGCCGCGCGTCCGTTGACCCCTCCGGACATGATCGCCCGCATCGTCGCAGAGCTGCGTACGGG
CCGCGGCGCTGTCATTCCGGCGGTTGCCGTCGCGGACACCATCAAATCGATCGACGTTCACGGTGACGTGATCGGCACTC
CCGACCGGGCGGGCCTGCGCGCCGTACAGACCCCACAGGGCTTCGCCGCCGACGTTCTCAGGCGTGCGTACGCGGCCGCA
GGTGATATCGCCACAGATGATGCCGCACTGGTTGAGCAGATCGGTGAGAGGGTTCACGTGGTGGAAGGCGACCGGTTGGC
CTTCAAAATCACCACGACACTCGACATGACATTGGCCGAGGCGATTCTCGGTGCTACGGAAGGCGTCCAATGA

Upstream 100 bases:

>100_bases
GCGGAGAACACCAACGCGGCCAAGGCCGACACCATCCTCGACGAGGTGCTCGCAGCTGCCTCGTAGGACCGCGGCGATCG
TTCCGGCCGCCGGTCTCGGT

Downstream 100 bases:

>100_bases
ACGCATTGCCCCGGGTGGGCATCGGTACCGATGTGCACCCCATCGAGGAGGGCAAGCCCTGTTGGTTGCTGGGACTGCTC
TTTTCCGATGAGAACGGATG

Product: putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Products: NA

Alternate protein names: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MRLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGSGATVVQGGAERTDSVRAGLAAVDAAD
WILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADTIKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYAAA
GDIATDDAALVEQIGERVHVVEGDRLAFKITTTLDMTLAEAILGATEGVQ

Sequences:

>Translated_210_residues
MRLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGSGATVVQGGAERTDSVRAGLAAVDAAD
WILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADTIKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYAAA
GDIATDDAALVEQIGERVHVVEGDRLAFKITTTLDMTLAEAILGATEGVQ
>Mature_210_residues
MRLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGSGATVVQGGAERTDSVRAGLAAVDAAD
WILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADTIKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYAAA
GDIATDDAALVEQIGERVHVVEGDRLAFKITTTLDMTLAEAILGATEGVQ

Specific function: Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) [H]

COG id: COG1211

COG function: function code I; 4-diphosphocytidyl-2-methyl-D-erithritol synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispD family [H]

Homologues:

Organism=Escherichia coli, GI1789104, Length=211, Percent_Identity=37.914691943128, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001228
- InterPro:   IPR018294 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.60 [H]

Molecular weight: Translated: 21509; Mature: 21509

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01295 ISPD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGSGATVVQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHEEEEECCHHHHHHHHHHCCCCCEEC
GGAERTDSVRAGLAAVDAADWILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADT
CCCHHHHHHHHHHHHHCHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
IKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYAAAGDIATDDAALVEQIGERVHV
HHHHCCCCCEECCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEE
VEGDRLAFKITTTLDMTLAEAILGATEGVQ
EECCEEEEEEECHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLGANTPKAFVSVGGRTMLQRCVDGLLASGAVDEVVVVVGADQLERAAALVGSGATVVQ
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCHHHEEEEECCHHHHHHHHHHCCCCCEEC
GGAERTDSVRAGLAAVDAADWILVHDAARPLTPPDMIARIVAELRTGRGAVIPAVAVADT
CCCHHHHHHHHHHHHHCHHCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
IKSIDVHGDVIGTPDRAGLRAVQTPQGFAADVLRRAYAAAGDIATDDAALVEQIGERVHV
HHHHCCCCCEECCCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCEEEE
VEGDRLAFKITTTLDMTLAEAILGATEGVQ
EECCEEEEEEECHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA