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The map label for this gene is plcN [H]

Identifier: 169627659

GI number: 169627659

Start: 556451

End: 557890

Strand: Direct

Name: plcN [H]

Synonym: MAB_0555

Alternate gene names: 169627659

Gene position: 556451-557890 (Clockwise)

Preceding gene: 169627658

Following gene: 169627660

Centisome position: 10.98

GC content: 65.49

Gene sequence:

>1440_bases
ATGAGCCCGCTGACCCGCCGCCGCCTGCTCACGTCGGCGGCGGGCACCGCGGCGTTCAGTGCCGCCGTCTCGCTCATGCC
CGCCAACCTCCAGCGTGTCCTGGCCCAGCCGGCACCCAGAAGCGGTTCGCTCAGGGACGTCGAGCACGTGGTGGTCCTCA
TGATGGAGAACCGGTCCTTCGATCATTACTTCGGCACCCTGTCCGGTGTCAGGGGCTTTGACGACCCGACCGCCGTCACC
CTCTCGACAGGTAAATCCGTCTTCCATCAGCCCGACCCGCAGAACCCCGACGGTTACTTGCTGCCCTTCCACCTCGACAC
CGCGGTGAACAGCGTGCAGAAGATCCCCACGACCAGTCACGCCTGGTCGGTGCAGCACGACTCGTGGAACCACGGGAAGA
TGGACAACTGGATGGCTGCTCATCGCAAGGCCGACGGTGAGCATTACCCGTATGTGATGGGCTATTACGAGCGGGCGGAC
ATTCCCTTTCATTTCGCGCTCGCCGAGGCGTTCACCGTCTGCGACAACTTTCACTCCTCGGTGATGGGGCCCACCTGGCC
CAACCGGATGATGTGGATGACCGGCACCATCGATCCCGACGCCGCGCACGGCGGCCCGATCATCCGGAATACCCCCGTGT
CCGGTGGCTATGGCTGGACCACCTACGCCGAACGGCTGGAGGCCGCCGGTGTGAGTTGGCGCGTGTATGCCGAAGAGGAC
GACTACGGCGGCTGCAATGTGTTGAAGCTATTCAGCCGCTTTCAGCGGAGTAGACCCGGGGAACCCTTATACGACAAGGG
GATAGCCCCCGTACGTGCCACGCAGTTCGAAGACGACGCGCGAGCGGGAAGATTGCCCGCGGTGTCCTGGCTCATCATGA
CGAGCACCGCGAGTGAACATCCGGACTATCGGCCGGCCGATGGCGCGGCGTACATCGCGAGCAAGATTGACGCGATCGCC
GCCAACCCCGAGGTGTGGGCCAAGACGGTATTCATCCTCAACTACGACGAGAACGATGGCCTGTTCGACCACGTGGTGCC
GCCGACGCCGCCGCCCGGTACTCCCGGAGAGTGGGTCAAGGGTGTGCCGATAGGCGGCGGATTCCGGGTGCCGGCCATCG
TGATTTCGCCGTGGTCGGTCGGCGGGTGGGTGGCCGGCGAGTCCTTTGACCACACCTCGGTACTGCGATTCCTTGAAGAG
TTCACGGGTGTGCGCGAGCCGAACATCTCGGGGTGGAGGCGCAAAACATTTGGGAATCTGCTCTCGGCCTTCGGGTTCGA
CAGCCCGGTGCGGCCGGCGCCGGAGTTGCCGGACACCGCTGCGGTGGTTGCGGCCGCCGATCGTACGGACACCCGGCCGC
CGCCGGTGATACCGCCAGCGCCGCAGACCAGCCCGGTTCAAGAACCGGGCTCGCGTCCGCGGCGGTACCCACGCCGCTAG

Upstream 100 bases:

>100_bases
CATCTGATGCACGACGATTCACCGAAGCTTTACCGCAGCGCCGTCTCCGACTTCCTCGCGGCGCCGGGTGCGCCAGGGGC
GTCGGTCGTAGCCTGAAGCG

Downstream 100 bases:

>100_bases
TAGCGCGTCCGGATGGCTTCCATTTCATGCCGTTGCCGCTCCAGATCGCGATCCTCGGCGAACGTGCCACCCATCGGCGC
GGCAATCCGGAACTGATCGA

Product: non-hemolytic phospholipase C

Products: NA

Alternate protein names: PLC-N; Phosphatidylcholine cholinephosphohydrolase; Phosphatidylcholine-hydrolyzing phospholipase C; PC-PLC [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVT
LSTGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSHAWSVQHDSWNHGKMDNWMAAHRKADGEHYPYVMGYYERAD
IPFHFALAEAFTVCDNFHSSVMGPTWPNRMMWMTGTIDPDAAHGGPIIRNTPVSGGYGWTTYAERLEAAGVSWRVYAEED
DYGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDARAGRLPAVSWLIMTSTASEHPDYRPADGAAYIASKIDAIA
ANPEVWAKTVFILNYDENDGLFDHVVPPTPPPGTPGEWVKGVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEE
FTGVREPNISGWRRKTFGNLLSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR

Sequences:

>Translated_479_residues
MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVT
LSTGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSHAWSVQHDSWNHGKMDNWMAAHRKADGEHYPYVMGYYERAD
IPFHFALAEAFTVCDNFHSSVMGPTWPNRMMWMTGTIDPDAAHGGPIIRNTPVSGGYGWTTYAERLEAAGVSWRVYAEED
DYGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDARAGRLPAVSWLIMTSTASEHPDYRPADGAAYIASKIDAIA
ANPEVWAKTVFILNYDENDGLFDHVVPPTPPPGTPGEWVKGVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEE
FTGVREPNISGWRRKTFGNLLSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR
>Mature_478_residues
SPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSFDHYFGTLSGVRGFDDPTAVTL
STGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSHAWSVQHDSWNHGKMDNWMAAHRKADGEHYPYVMGYYERADI
PFHFALAEAFTVCDNFHSSVMGPTWPNRMMWMTGTIDPDAAHGGPIIRNTPVSGGYGWTTYAERLEAAGVSWRVYAEEDD
YGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDARAGRLPAVSWLIMTSTASEHPDYRPADGAAYIASKIDAIAA
NPEVWAKTVFILNYDENDGLFDHVVPPTPPPGTPGEWVKGVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEF
TGVREPNISGWRRKTFGNLLSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR

Specific function: Hydrolyzes phosphatidylserine as well as phosphatidylcholine [H]

COG id: COG3511

COG function: function code M; Phospholipase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial phospholipase C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007312
- InterPro:   IPR008475
- InterPro:   IPR017767
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05506 DUF756; PF04185 Phosphoesterase [H]

EC number: =3.1.4.3 [H]

Molecular weight: Translated: 52621; Mature: 52489

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSF
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCEEEEEEECCCCC
DHYFGTLSGVRGFDDPTAVTLSTGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSH
HHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCC
AWSVQHDSWNHGKMDNWMAAHRKADGEHYPYVMGYYERADIPFHFALAEAFTVCDNFHSS
EEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHH
VMGPTWPNRMMWMTGTIDPDAAHGGPIIRNTPVSGGYGWTTYAERLEAAGVSWRVYAEED
CCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
DYGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDARAGRLPAVSWLIMTSTASEH
CCCCHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCHHCCCCCEEEEEEEECCCCCC
PDYRPADGAAYIASKIDAIAANPEVWAKTVFILNYDENDGLFDHVVPPTPPPGTPGEWVK
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
GVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRRKTFGNL
CCCCCCCCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR
HHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPLTRRRLLTSAAGTAAFSAAVSLMPANLQRVLAQPAPRSGSLRDVEHVVVLMMENRSF
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCEEEEEEECCCCC
DHYFGTLSGVRGFDDPTAVTLSTGKSVFHQPDPQNPDGYLLPFHLDTAVNSVQKIPTTSH
HHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCCCCCCCEEEEEEHHHHHHHHHHCCCCCC
AWSVQHDSWNHGKMDNWMAAHRKADGEHYPYVMGYYERADIPFHFALAEAFTVCDNFHSS
EEEECCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHH
VMGPTWPNRMMWMTGTIDPDAAHGGPIIRNTPVSGGYGWTTYAERLEAAGVSWRVYAEED
CCCCCCCCCEEEEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCC
DYGGCNVLKLFSRFQRSRPGEPLYDKGIAPVRATQFEDDARAGRLPAVSWLIMTSTASEH
CCCCHHHHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCHHCCCCCEEEEEEEECCCCCC
PDYRPADGAAYIASKIDAIAANPEVWAKTVFILNYDENDGLFDHVVPPTPPPGTPGEWVK
CCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEE
GVPIGGGFRVPAIVISPWSVGGWVAGESFDHTSVLRFLEEFTGVREPNISGWRRKTFGNL
CCCCCCCCCCCEEEEECCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LSAFGFDSPVRPAPELPDTAAVVAAADRTDTRPPPVIPPAPQTSPVQEPGSRPRRYPRR
HHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120196; 10984043 [H]